Area of office space.

No definition available.

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- Definition

Lease term commencement date.

+ References

No definition available.

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- Definition

The amount that may be deducted from consideration due to Licensor 2 as a percentage of consideration paid to Licensor 1, whereby Licensor 1 is the identified party.

+ References

No definition available.

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- Definition

The amount of expense recognized during the period related to milestones. Such amount may include, but is not limited to, amounts due for attainment of milestones as well as deductions granted as part of a license agreement.

+ References

No definition available.

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- Definition

Amount of payment due upon reaching milestone.

+ References

No definition available.

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- Definition

The minimum annual royalty payment that is required under a contractual arrangement.

+ References

No definition available.

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- Definition

Payment for license agreements.

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No definition available.

+ Details

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- Definition

Sublease annual base rent.

+ References

No definition available.

+ Details

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- Definition

Date which lease or group of leases is set to expire, in YYYY-MM-DD format.

+ References

No definition available.

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- Definition

Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478964/842-20-50-3

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Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

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- Definition

Amount of operating lease expense. Excludes sublease income.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 45
-Paragraph 4
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479041/842-20-45-4

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- Definition

Present value of lessee's discounted obligation for lease payments from operating lease, classified as noncurrent.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 45
-Paragraph 1
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479041/842-20-45-1

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- Definition

Amount of lessee's right to use underlying asset under operating lease.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 45
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-Subparagraph (a)
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-URI https://asc.fasb.org/1943274/2147479041/842-20-45-1

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- Definition

Weighted average discount rate for operating lease calculated at point in time.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
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-URI https://asc.fasb.org/1943274/2147478964/842-20-50-4

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Data Type:	dtr-types:percentItemType
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Period Type:	instant

- Definition

Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 842
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 53
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479589/842-20-55-53

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

Amount of cash restricted as to withdrawal or usage. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 944
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(2))
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Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
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Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
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-Publisher FASB
-URI https://asc.fasb.org/1943274/2147478546/942-210-S99-1

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- Definition

This element represents money paid in advance to protect the provider of a product or service, such as a lessor, against damage or nonpayment by the buyer or tenant (lessee) during the term of the agreement. Such damages may include physical damage to the property, theft of property, and other contractual breaches. Security deposits held may be interest or noninterest bearing.

+ References

No definition available.

+ Details

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Balance Type:	credit
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- Details

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Commitments and Contingencies - Additional Information (Detail) $ in Thousands										1 Months Ended	3 Months Ended		6 Months Ended
	Oct. 16, 2023	Mar. 09, 2023 ft²	Aug. 09, 2021	Oct. 27, 2020 USD ($)	Aug. 04, 2020	May 28, 2020 USD ($) ft²	Dec. 11, 2019 USD ($)	Aug. 08, 2019 ft²	Nov. 05, 2018	Oct. 31, 2022 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2024 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2024 USD ($)	Dec. 31, 2024 USD ($)	Oct. 31, 2024 USD ($)	May 10, 2024 USD ($)	Oct. 01, 2023 USD ($)	Sep. 01, 2023 USD ($)	Nov. 30, 2016 USD ($)
Other Commitments [Line Items]
Operating lease liabilities											$ 3,485		$ 3,485		$ 4,057
Operating lease right-of-use assets											$ 2,468		$ 2,468		$ 2,838
Weighted average remaining lease term in years											4 years		4 years		4 years 6 months
Weighted average discount rate											11.00%		11.00%		11.00%
Lease expenses											$ 100	$ 100	$ 300	$ 300
Pennsylvania [Member] \| Office [Member]
Other Commitments [Line Items]
Operating lease term								3 years 6 months
Lease extension period								3 years
Lease term commencement date		Sep. 01, 2023						Feb. 15, 2020
Operating lease liabilities																			$ 500
Operating lease right-of-use assets																			$ 500
Area of office space \| ft²		4,642						4,642
Lease term expiration date								Aug. 31, 2023
Pennsylvania [Member] \| Office and Lab [Member]
Other Commitments [Line Items]
Lease extension period									2 years
Lease term commencement date									Jan. 01, 2019
Lease term expiration date			Dec. 31, 2022		Dec. 31, 2021				Dec. 31, 2020
Pennsylvania [Member] \| Additional Office [Member]
Other Commitments [Line Items]
Lease term commencement date		Oct. 01, 2023
Operating lease liabilities																		$ 300
Operating lease right-of-use assets																		$ 300
Area of office space \| ft²		3,462
Pennsylvania [Member] \| Lab Space [Member]
Other Commitments [Line Items]
Operating lease term	4 years
Lease term commencement date	May 10, 2024
Operating lease liabilities																	$ 500
Operating lease right-of-use assets																	$ 500
Massachusetts [Member] \| Office [Member]
Other Commitments [Line Items]
Area of office space \| ft²						17,705
Lease term expiration date						Oct. 30, 2029
Massachusetts [Member] \| Office Sublease [Member]
Other Commitments [Line Items]
Lease term commencement date				Dec. 04, 2020
Lease term expiration date				Oct. 30, 2029
Massachusetts [Member] \| Letter of Credit \| Office [Member]
Other Commitments [Line Items]
Letter of credit						$ 1,300										$ 600
Massachusetts [Member] \| First Sublease Year [Member] \| Office Sublease [Member]
Other Commitments [Line Items]
Annual base rent				$ 800
Massachusetts [Member] \| First Sublease Year [Member] \| Letter of Credit \| Office Sublease [Member]
Other Commitments [Line Items]
Lease security deposits letters of credit				800
Massachusetts [Member] \| Final Sublease Year [Member] \| Office Sublease [Member]
Other Commitments [Line Items]
Annual base rent				1,000
Massachusetts [Member] \| Sixth Sublease Year \| Letter of Credit \| Office Sublease [Member]
Other Commitments [Line Items]
Lease security deposits letters of credit				$ 400
WFUHS [Member]
Other Commitments [Line Items]
License agreement consideration deduction percentage																				60.00%
WFUHS [Member] \| Maximum [Member]
Other Commitments [Line Items]
Milestone payments																				$ 2,600
IU [Member]
Other Commitments [Line Items]
License agreement consideration deduction percentage																				20.00%
IU [Member] \| Maximum [Member]
Other Commitments [Line Items]
Milestone payments																				$ 2,600
Annual royalty pay obligation																				$ 100
WFUHS and IU [Member] \| Research and Development Expenses [Member]
Other Commitments [Line Items]
Milestone expenses										$ 300
WFUHS and IU [Member] \| Maximum [Member]
Other Commitments [Line Items]
Payment for license agreements							$ 100