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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2024 | Mar. 31, 2023
Operating activities: |  |
Net loss | $ (53,721) | $ (35,625)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 7,373 | 2,195
Non-cash operating lease expense | 791 | 799
Depreciation and amortization | 158 | 158
Net accretion of investments in marketable securities | (1,147) | (892)
Other noncash expenses |  | 15
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 7,351 | 7,858
Accounts payable | 1,155 | (6,012)
Accrued liabilities | (4,113) | (736)
Operating lease liabilities | (802) | (801)
Net cash used in operating activities | (42,955) | (33,041)
Investing activities: |  |
Purchases of marketable securities | (185,804) | (41,483)
Proceeds from sales and maturities of marketable securities | 36,578 | 44,336
Purchases of property and equipment |  | (36)
Cash paid for acquisition of assets | (775) |
Net cash (used in) provided by investing activities | (150,001) | 2,817
Financing activities: |  |
Proceeds from exercise of stock options | 1,845 | 602
Repurchase of unvested early exercised shares |  | (491)
Payments for deferred offering costs |  | (10)
Net cash provided by financing activities | 1,845 | 101
Net change in cash and cash equivalents and restricted cash | (191,111) | (30,123)
Cash and cash equivalents and restricted cash at beginning of year | 375,251 | 242,206
Cash and cash equivalents and restricted cash at end of year | 184,140 | 212,083
Components of cash and restricted cash: |  |
Cash and cash equivalents | 182,927 | 210,870
Restricted Cash | 1,213 | 1,213
Total cash and cash equivalents and restricted cash | $ 184,140 | $ 212,083

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