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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Operating activities:    
Net loss $ (53,721) $ (35,625)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 7,373 2,195
Non-cash operating lease expense 791 799
Depreciation and amortization 158 158
Net accretion of investments in marketable securities (1,147) (892)
Other noncash expenses   15
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 7,351 7,858
Accounts payable 1,155 (6,012)
Accrued liabilities (4,113) (736)
Operating lease liabilities (802) (801)
Net cash used in operating activities (42,955) (33,041)
Investing activities:    
Purchases of marketable securities (185,804) (41,483)
Proceeds from sales and maturities of marketable securities 36,578 44,336
Purchases of property and equipment   (36)
Cash paid for acquisition of assets (775)  
Net cash (used in) provided by investing activities (150,001) 2,817
Financing activities:    
Proceeds from exercise of stock options 1,845 602
Repurchase of unvested early exercised shares   (491)
Payments for deferred offering costs   (10)
Net cash provided by financing activities 1,845 101
Net change in cash and cash equivalents and restricted cash (191,111) (30,123)
Cash and cash equivalents and restricted cash at beginning of year 375,251 242,206
Cash and cash equivalents and restricted cash at end of year 184,140 212,083
Components of cash and restricted cash:    
Cash and cash equivalents 182,927 210,870
Restricted Cash 1,213 1,213
Total cash and cash equivalents and restricted cash $ 184,140 $ 212,083