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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Summary of Stock Option Activity | Stock Option Activity
|  | Outstanding Stock Options |  |  | Weighted- Average Exercise Price Per Share |  |  | Weighted- Average Remaining Contractual Term (years) |  |  | Aggregate Intrinsic Value |
|  | (in thousands, except per share amounts and years) |
Outstanding as of December 31, 2024 |  |  | 13,927 |  |  | $ | 9.20 |  |  |  | 7.8 |  |  | $ | 44,953 |
Granted |  |  | 11,995 |  |  |  | 1.68 |  |  |  |  |  |  |
Exercised |  |  | — |  |  |  | — |  |  |  |  |  |  |
Canceled and forfeited |  |  | (2,166 | ) |  |  | 8.16 |  |  |  |  |  |  |
Expired |  |  | (121 | ) |  |  | 3.58 |  |  |  |  |  |  |
Outstanding as of March 31, 2025 |  |  | 23,635 |  |  | $ | 5.51 |  |  |  | 8.9 |  |  | $ | — |
Exercisable as of March 31, 2025 |  |  | 6,490 |  |  | $ | 7.54 |  |  |  | 7.6 |  |  | $ | — |
Summary of Restricted Stock Activity | The following table summarizes the Company’s restricted stock activity:
|  | Shares of Restricted Common Stock |  |  | Weighted- Average Grant Date Fair Value Per Share |  |  | Shares of Restricted Stock Units |  |  | Weighted- Average Grant Date Fair Value Per Share |
|  | (in thousands, except per share amounts) |
Outstanding and unvested as of December 31, 2024 |  |  | 371 |  |  | $ | 10.82 |  |  |  | 1,441 |  |  | $ | 17.32 |
Granted |  |  | — |  |  |  | — |  |  |  | — |  |  |  | — |
Vested |  |  | (29 | ) |  |  | 11.50 |  |  |  | (269 | ) |  |  | 18.07 |
Forfeited and expired |  |  | — |  |  |  | — |  |  |  | — |  |  |  | — |
Cancelled |  |  | (231 | ) |  |  | 8.87 |  |  |  | (66 | ) |  |  | 18.07 |
Outstanding and unvested as of March 31, 2025 |  |  | 111 |  |  | $ | 14.67 |  |  |  | 1,106 |  |  | $ | 17.08 |
Summary of Stock-Based Compensation Expense Recognized | The following table summarizes total stock-based compensation included in the Company’s condensed consolidated statements of operations and comprehensive loss:
|  | Three Months Ended March 31, |
|  | 2025 |  |  | 2024 |
|  | (in thousands) |
Research and development |  | $ | 3,748 |  |  | $ | 2,812 |
General and administrative |  |  | 5,576 |  |  |  | 4,561 |
Total stock-based compensation |  | $ | 9,324 |  |  | $ | 7,373 |

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