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Acquisitions of Assets - Additional Information (Details) | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Dec. 31, 2023 USD ($) shares | Nov. 30, 2023 USD ($) | Feb. 28, 2022 USD ($) | Sep. 30, 2021 USD ($) Agreements shares | Jun. 30, 2020 USD ($) | Mar. 31, 2025 USD ($) Milestones | Dec. 31, 2023 USD ($) | Dec. 31, 2023 USD ($)
Amgen Inc. |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Number of license agreements | Agreements |  |  |  | 2 |  |  |  |
Vanderbilt IPR&D Assets |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration deemed due or payable |  |  |  |  |  | $ 0 |  |
BlackThorn Merger Agreement |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration, milestone payment settled in cash |  |  |  |  | $ 10,000,000 |  |  |
Number of milestone achieved | Milestones |  |  |  |  |  | 0 |  |
BlackThorn Merger Agreement | BlackThorn Therapeutics, Inc. |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration deemed due or payable |  |  |  |  |  | $ 0 |  |
Contingent consideration payable in cash | $ 2,300,000 |  |  |  |  |  |  |
Acquired in-process research and developed expense |  |  |  |  |  |  | $ 60,800,000 |
BlackThorn Merger Agreement | BlackThorn Therapeutics, Inc. | Common Stock |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Shares issued based on volume weighted average price per share prior to date milestone was met | shares | 6,072,445 |  |  |  |  |  |  |
BlackThorn Merger Agreement | navacaprant |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Milestone payment due description |  |  |  |  |  | milestone payment that became due in October 2023 upon dosing the first patient in the Phase 3 clinical trial for navacaprant, |  |
BlackThorn Merger Agreement | navacaprant | Maximum | Development and Regulatory Approval Milestones |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration |  |  |  |  | 365,000,000 |  |  |
BlackThorn Merger Agreement | navacaprant | Maximum | Sales-based Milestones |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration |  |  |  |  | 450,000,000 |  |  |
BlackThorn Merger Agreement | NMRA-511 | Maximum | Development and Regulatory Approval Milestones |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration |  |  |  |  | 100,000,000 |  |  |
BlackThorn Merger Agreement | NMRA-511 | Maximum | Sales-based Milestones |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration |  |  |  |  | $ 100,000,000 |  |  |
BlackThorn Carveout Plan |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Number of milestone achieved | Milestones |  |  |  |  |  | 0 |  |
Contingent consideration deemed due or payable |  |  |  |  |  | $ 0 |  |
Asset acquisition compensation recognized and paid |  |  |  |  |  |  |  | $ 1,800,000
Amgen Inc. Licenses | Amgen Inc. |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Number of milestone achieved | Milestones |  |  |  |  |  | 0 |  |
Contingent consideration deemed due or payable |  |  |  |  |  | $ 0 |  |
Amgen Inc. Licenses | Amgen Inc. | Series A-2 |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Upfront consideration transferred shares | shares |  |  |  | 20,000,000 |  |  |  |
Acquisition date fair value of shares transferred |  |  |  | $ 57,000,000 |  |  |  |
Amgen Inc. Licenses | Amgen Inc. | Maximum | Case One |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration payable in cash |  |  |  | 360,000,000 |  |  |  |
Amgen Inc. Licenses | Amgen Inc. | Maximum | Commercial Milestone Payment | Case Two |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration payable in cash |  |  |  | $ 360,000,000 |  |  |  |
Vanderbilt License |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration, milestone payment settled in cash |  | $ 2,000,000 |  |  |  |  |  |
Number of milestone achieved | Milestones |  |  |  |  |  | 0 |  |
Acquired in-process research and development |  |  |  |  |  |  | $ 800,000 |
Vanderbilt License | Maximum | Achievement of Specified Development Events |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration payable in cash |  |  | $ 42,400,000 |  |  |  |  |
Vanderbilt License | Maximum | Achievement of Specified Commercialization Events |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Contingent consideration payable in cash |  |  | 380,000,000 |  |  |  |  |
Vanderbilt License | Vanderbilt IPR&D Assets |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |
Upfront cash payment |  |  | $ 13,000,000 |  |  |  |  |

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