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Organization and Liquidity - Additional information (Details) $ in Thousands | Mar. 31, 2025 USD ($) Program | Dec. 31, 2024 USD ($)
--- | --- | ---
Organization and Liquidity [Line items] |  |
Number of clinical and preclinical neuroscience programs | Program | 7 |
Accumulated deficit | $ (1,015,213) | $ (947,221)
Liquidity |  |
Organization and Liquidity [Line items] |  |
Accumulated deficit | 1,015,200 |
Cash, cash equivalents, and marketable securities | $ 249,400 |

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