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Segment Reporting - Schedule of Segment Loss Including Significant Segment Expenses (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Segment Reporting [Abstract]
Navacaprant (NMRA-140) program	$ (24,493)	$ (24,319)
M4 PAM programs	(2,882)	(3,524)
NMRA-511 program	(2,580)	(1,887)
Preclinical programs	(1,002)	(2,409)
Research and development personnel-related costs	(12,326)	(10,875)
General and administrative expense	(18,785)	(14,317)
Interest income	3,074	6,365
Other segment items	(8,998)	(2,755)
Net loss	$ (67,992)	$ (53,721)

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