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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Revenue	$ 140	$ 1,526	$ 1,235	$ 3,022
Operating expenses:
Research and development	9,564	7,558	16,691	14,804
Selling, general and administrative	3,736	2,212	7,724	4,534
Total operating expenses	13,300	9,770	24,415	19,338
Loss from operations	(13,160)	(8,244)	(23,180)	(16,316)
Investment income	2	6	8	18
Interest expense	(589)	(453)	(1,176)	(947)
Other income (expense), net	155	152	267	(189)
Net loss	(13,592)	(8,539)	(24,081)	(17,434)
Comprehensive loss	$ (13,592)	$ (8,539)	$ (24,081)	$ (17,434)
Basic and diluted net loss per share (USD per share)	$ (0.48)	$ (0.38)	$ (0.89)	$ (0.78)
Weighted-average shares used to compute basic and diluted net loss per share (shares)	28,199,739	22,466,540	27,053,946	22,450,722

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