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Organization and Significant Accounting Policies (Details)
$ in Thousands
9 Months Ended
Jan. 01, 2019
USD ($)
Oct. 01, 2018
Sep. 30, 2019
USD ($)
segment
item
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Number of operating segments | segment     1
Number of phase 3 programs | item     3
Pass-through period for OMIDRIA   2 years  
Right of use assets     $ 21,302
Lease liabilities     $ 29,169
Accounting Standards Update 2016-02      
New Accounting Pronouncements or Change in Accounting Principle [Line Items]      
Lease, Practical Expedients, Package true    
Right of use assets $ 17,700    
Lease liabilities 26,400    
Deferred Rent Credit $ (8,700)