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CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Current assets: |  |
Cash and cash equivalents | $ 10,501 | $ 3,084
Short-term investments | 124,452 | 57,704
Receivables, net | 3,841 | 35,185
Inventory | 1,355 | 1,147
Prepaid expense and other assets | 11,136 | 6,625
Total current assets | 151,285 | 103,745
Property and equipment, net | 2,551 | 3,829
Right of use assets | 25,526 | 27,082
Restricted investments | 1,055 | 1,154
Advanced payments, non-current | 625 | 1,159
Total assets | 181,042 | 136,969
Current liabilities: |  |
Accounts payable | 4,199 | 5,328
Accrued expenses | 28,755 | 46,627
Current portion of lease liabilities | 3,782 | 3,504
Total current liabilities | 36,736 | 55,459
Lease liabilities, non-current | 28,770 | 32,318
Unsecured convertible senior notes, net | 236,288 | 158,213
Commitments and contingencies (Note 10) |  |
Shareholders' deficit: |  |
Preferred stock, par value $0.01 per share, 20,000,000 shares authorized; none issued and outstanding at December 31, 2020 and December 31, 2019. |  |
Common stock, par value $0.01 per share, 150,000,000 shares authorized at December 31, 2020 and December 31, 2019; 61,671,231 and 54,200,810 shares issued and outstanding at December 31, 2020 and December 31, 2019, respectively. | 616 | 542
Additional paid-in capital | 751,304 | 625,048
Accumulated deficit | (872,672) | (734,611)
Total shareholders' deficit | (120,752) | (109,021)
Total liabilities and shareholders' deficit | $ 181,042 | $ 136,969

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