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Certain Balance Sheet Accounts - Property and Equipment, Net (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Property, Plant and Equipment [Line Items]      
Total cost $ 10,198 $ 9,864  
Less accumulated depreciation and amortization (7,647) (6,035)  
Total property and equipment, net 2,551 3,829  
Depreciation and amortization 1,616 1,790 $ 962
Finance leases      
Property, Plant and Equipment [Line Items]      
Total cost 5,690 5,474  
Laboratory equipment      
Property, Plant and Equipment [Line Items]      
Total cost 2,898 2,844  
Computer equipment      
Property, Plant and Equipment [Line Items]      
Total cost 985 921  
Office equipment and furniture      
Property, Plant and Equipment [Line Items]      
Total cost $ 625 $ 625