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CONSOLIDATED STATEMENTS OF SHAREHOLDERS' DEFICIT - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Total
Balance (in shares) at Dec. 31, 2017 48,211,226      
Balance at Dec. 31, 2017 $ 482 $ 520,072 $ (523,368) $ (2,814)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuance of common stock upon exercise of stock options $ 8 6,724   6,732
Issuance of common stock upon exercise of stock options (in shares) 800,458      
Issuance of warrants in connection with debt amendment   1,424   1,424
Stock-based compensation expense   11,713   11,713
Equity component of Notes, net of issuance costs   55,655   55,655
Purchases of Capped Calls   (33,180)   (33,180)
Income tax benefit related to issuance of notes   (12,929)   (12,929)
Net loss     (126,757) (126,757)
Balance (in shares) at Dec. 31, 2018 49,011,684      
Balance at Dec. 31, 2018 $ 490 549,479 (650,125) (100,156)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuance of common stock in direct offering, net of offering costs $ 44 54,194   54,238
Issuance of common stock in direct offering, net of offering costs (in shares) 4,389,311      
Issuance of common stock upon exercise of stock options $ 8 7,590   7,598
Issuance of common stock upon exercise of stock options (in shares) 799,815      
Stock-based compensation expense   13,785   13,785
Net loss     (84,486) (84,486)
Balance (in shares) at Dec. 31, 2019 54,200,810      
Balance at Dec. 31, 2019 $ 542 625,048 (734,611) (109,021)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuance of common stock in direct offering, net of offering costs $ 69 93,606   93,675
Issuance of common stock in direct offering, net of offering costs (in shares) 6,900,000      
Issuance of common stock upon exercise of stock options $ 5 5,017   $ 5,022
Issuance of common stock upon exercise of stock options (in shares) 556,421     556,421
Issuance of common stock upon grant of restricted stock awards   155   $ 155
Issuance of common stock upon grant of restricted stock awards (in shares) 14,000      
Stock-based compensation expense   14,770   14,770
Equity component of Notes, net of issuance costs   61,628   61,628
Purchases of Capped Calls   (23,223)   (23,223)
Equity component of early extinguishment of 2023 Notes   (22,073)   (22,073)
Termination of the 2023 Capped Call contracts related to debt repurchased   8,387   8,387
Income tax benefit related to issuance of notes   (12,011)   (12,011)
Net loss     (138,061) (138,061)
Balance (in shares) at Dec. 31, 2020 61,671,231      
Balance at Dec. 31, 2020 $ 616 $ 751,304 $ (872,672) $ (120,752)