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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2022
Mar. 08, 2023
Jun. 30, 2022
Document Document and Entity Information [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2022    
Entity File Number 001-34475    
Entity Registrant Name OMEROS CORPORATION    
Entity Incorporation, State or Country Code WA    
Entity Tax Identification Number 91-1663741    
Entity Address, Address Line One 201 Elliott Avenue West    
Entity Address, City or Town Seattle    
Entity Address, State or Province WA    
Entity Address, Postal Zip Code 98119    
City Area Code 206    
Local Phone Number 676-5000    
Title of 12(b) Security Common Stock    
Trading Symbol OMER    
Security Exchange Name NASDAQ    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Entity Shell Company false    
Entity Voluntary Filers No    
Entity Well-known Seasoned Issuer No    
Entity Common Stock, Shares Outstanding   62,828,765  
Current Fiscal Year End Date --12-31    
Entity Public Float     $ 165,588,454
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Entity Central Index Key 0001285819    
Amendment Flag false    
Auditor Name Ernst & Young LLP    
Auditor Firm ID 42    
Auditor Location Seattle, Washington