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Note 13 - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2023 | Dec. 31, 2022
--- | --- | ---
Net operating loss carryforwards | $ 95,183 | $ 85,887
Research and development tax credits | 92,837 | 78,992
Capitalized research and development | 39,318 | 21,864
OMIDRIA royalty obligation | 28,903 | 28,938
Stock-based compensation | 10,132 | 12,517
Lease liability | 5,085 | 5,926
Other | 10,283 | 9,234
Total deferred tax assets | 281,741 | 243,358
OMIDRIA contract royalty asset | (38,832) | (34,883)
Right of use assets | (4,304) | (4,987)
Property and equipment | (122) | (288)
Total deferred tax liabilities | (43,258) | (40,158)
Net deferred tax assets before valuation allowance | 238,483 | 203,200
Less valuation allowance | (238,483) | (203,200)
Net deferred tax liabilities | $ 0 | $ 0

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