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Note 2 - Significant Accounting Policies (Details Textual) - USD ($) $ in Thousands |  |  | 1 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Sep. 30, 2022 | Dec. 23, 2021 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Mar. 31, 2023 | Dec. 29, 2022 | Sep. 30, 2020
Percentage of Royalty Receivable on Sale of Product Rights |  | 50.00% |  | 30.00% |  |  |  |  |  |
Milestone Payment Receivable |  |  | $ 0 | $ 200,000 | $ 0 | $ 200,000 |  |  |  |
Percentage Of Interest Earned on Outstanding Contract Royalty Asset |  |  |  |  |  |  |  | 11.00% |  |
Proceeds From Royalty Obligation |  |  |  |  | 0 | 125,000 | $ 0 |  |  |
Repayments of Convertible Debt |  |  |  |  | 99,873 | (0) | (0) |  |  |
Gain (Loss) on Extinguishment of Debt |  |  |  |  | 4,112 | 0 | 0 |  |  |
Asset Impairment Charges |  |  |  |  | 0 | 0 | 0 |  |  |
Advertising Expense |  |  |  |  | $ 0 | 0 | $ 800 |  |  |
Convertible Senior Notes 2023 [Member] |  |  |  |  |  |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  |  | 6.25% |  | 6.25% |  |  |  |  |
Convertible Senior Notes 2026 [Member] |  |  |  |  |  |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  |  | 5.25% |  | 5.25% |  |  |  |  | 5.25%
Repayments of Convertible Debt |  |  | $ 9,100 |  |  |  |  |  |  |
Gain (Loss) on Extinguishment of Debt |  |  | $ 4,100 |  |  |  |  |  |  |
Minimum [Member] |  |  |  |  |  |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 3 years |  | 3 years |  |  |  |  |
Maximum [Member] |  |  |  |  |  |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 10 years |  | 10 years |  |  |  |  |
Discontinued Operations, Disposed of by Sale [Member] | Omidria Assets Disposal [Member] |  |  |  |  |  |  |  |  |  |
Percentage of Royalty Receivable on Sale of Product Rights |  | 50.00% |  | 30.00% |  |  |  |  |  |
Milestone Payment Receivable from Sale of Royalty Under Asset Purchase Agreement |  |  |  | $ 200,000 |  | $ 200,000 |  |  | $ 200,000 |
DRI Healthcare Acquisition LP [Member] |  |  |  |  |  |  |  |  |  |
Proceeds From Royalty Obligation | $ 125,000 |  |  |  |  |  |  |  |  |
Maximum Royalty Payable Percentage |  |  | 9.40% |  | 9.40% |  |  | 9.40% |  |

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