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Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Costs and expenses:      
Research and development $ 114,870 $ 112,721 $ 118,775
Selling, general and administrative 49,660 50,668 54,842
Total costs and expenses 164,530 163,389 173,617
Loss from operations (164,530) (163,389) (173,617)
Interest expense (30,844) (22,702) (19,669)
Interest and other income 16,342 4,062 1,740
Gain on early extinguishment of convertible senior notes 4,112 0 0
Net loss from continuing operations (174,920) (182,029) (191,546)
Net income from discontinued operations, net of tax 57,107 229,446 385,781
Net income (loss) $ (117,813) $ 47,417 $ 194,235
Basic and diluted net income (loss) per share:      
Net loss from continuing operations (in dollars per share) $ (2.79) $ (2.9) $ (3.07)
Net income from discontinued operations (in dollars per share) 0.91 3.66 6.19
Net income (loss) (in dollars per share) $ (1.88) $ 0.76 $ 3.12
Weighted-average shares used to compute basic and diluted net income (loss) per share (in shares) 62,739,227 62,737,091 62,344,100