Note 13 - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2023	Dec. 31, 2022
Net operating loss carryforwards	$ 95,183	$ 85,887
Research and development tax credits	92,837	78,992
Capitalized research and development	39,318	21,864
OMIDRIA royalty obligation	28,903	28,938
Stock-based compensation	10,132	12,517
Lease liability	5,085	5,926
Other	10,283	9,234
Total deferred tax assets	281,741	243,358
OMIDRIA contract royalty asset	(38,832)	(34,883)
Right of use assets	(4,304)	(4,987)
Property and equipment	(122)	(288)
Total deferred tax liabilities	(43,258)	(40,158)
Net deferred tax assets before valuation allowance	238,483	203,200
Less valuation allowance	(238,483)	(203,200)
Net deferred tax liabilities	$ 0	$ 0

Amount, before allocation of valuation allowance, of deferred tax asset attributable to Section 174 R&D capitalization.

No definition available.

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- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to lease liability.

+ References

No definition available.

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- Definition

Amount of deferred tax assets, net of deferred tax liabilities before valuation allowance.

+ References

No definition available.

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Amount, before allocation of valuation allowance, of deferred tax asset attributable to royalty obligation.

+ References

No definition available.

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Amount of deferred tax liability attributable to taxable temporary differences from the gain on discontinued operation.

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Amount of deferred tax liability attributable to taxable temporary differences from right of use assets.

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No definition available.

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- Definition

Amount of deferred tax liability attributable to taxable temporary differences.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences, classified as other.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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Amount, after deferred tax asset, of deferred tax liability attributable to taxable differences without jurisdictional netting.

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Amount of deferred tax liability attributable to taxable temporary differences from property, plant, and equipment.

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