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Note 12 - Stock-based Compensation (Tables)

9 Months Ended

Sep. 30, 2024

Notes Tables

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

		Three Months Ended								Nine Months Ended
​		September 30,								September 30,
​		2024				2023				2024				2023
​		(In thousands)								(In thousands)
Continuing operations		​				​				​				​
Research and development		$	1,063			$	1,305			$	3,146			$	3,710
Selling, general and administrative			1,578				2,054				4,921				5,456
Total stock-based compensation in continuing operations			2,641				3,359				8,067				9,166
Discontinued operations			—				(124	)			—				(207	)
Total stock-based compensation		$	2,641			$	3,235			$	8,067			$	8,959

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

​		Three Months Ended				Nine Months Ended
​		September 30, 2024				September 30, 2024
Estimated weighted-average fair value		$	3.06			$	2.60
Weighted-average assumptions:		​				​
Expected volatility			96	%			95	%
Expected life, in years			7.4				7.2
Risk-free interest rate			4.22	%			4.36	%
Expected dividend yield			—	%			—	%

Share-Based Payment Arrangement, Activity [Table Text Block]

​		​				Weighted-				​				​
​		​				Average				​				Aggregate
​		​				Exercise				Remaining				Intrinsic
​		Options				Price per				Contractual Life				Value
​		Outstanding				Share				(In years)				(In thousands)
Balance at December 31, 2023			15,255,154			$	9.50
Granted			3,280,500				3.13
Exercised			(16,404	)			3.19
Forfeited			(386,181	)			6.91
Balance at September 30, 2024			18,133,069			$	8.41				6.0			$	6,168
Vested and expected to vest at September 30, 2024			17,503,959			$	8.58				5.9			$	5,677
Exercisable at September 30, 2024			12,133,698			$	10.75				4.5			$	1,421

X

- Definition

Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

+ References

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480429/718-10-50-2

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- Definition

Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value.

+ References

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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