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v3.23.3

Condensed Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands | Total | Common Stock | Additional Paid-in Capital | Accumulated Deficit | Accumulated Other Comprehensive Loss
--- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2021 |  | 142,623,065 |  |  |
Beginning balance at Dec. 31, 2021 | $ 916,406 | $ 142 | $ 1,822,179 | $ (903,348) | $ (2,567)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 715,961 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 283 | $ 1 | 282 |  |
Vesting of early exercised common stock | 1,228 |  | 1,228 |  |
Stock-based compensation | 22,315 |  | 22,315 |  |
Employee stock purchase plan (in shares) |  | 230,876 |  |  |
Employee stock purchase plan | 1,530 |  | 1,530 |  |
Net loss | (79,850) |  |  | (79,850) |
Net unrealized gain (loss) on available-for-sale investments | (6,682) |  |  |  | (6,682)
Ending balance (in shares) at Mar. 31, 2022 |  | 143,569,902 |  |  |
Ending balance at Mar. 31, 2022 | 855,230 | $ 143 | 1,847,534 | (983,198) | (9,249)
Beginning balance (in shares) at Dec. 31, 2021 |  | 142,623,065 |  |  |
Beginning balance at Dec. 31, 2021 | 916,406 | $ 142 | 1,822,179 | (903,348) | (2,567)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Net loss | (237,785) |  |  |  |
Net unrealized gain (loss) on available-for-sale investments | (10,391) |  |  |  |
Ending balance (in shares) at Sep. 30, 2022 |  | 144,031,588 |  |  |
Ending balance at Sep. 30, 2022 | 739,961 | $ 144 | 1,893,908 | (1,141,133) | (12,958)
Beginning balance (in shares) at Mar. 31, 2022 |  | 143,569,902 |  |  |
Beginning balance at Mar. 31, 2022 | 855,230 | $ 143 | 1,847,534 | (983,198) | (9,249)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 153,269 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 25 | $ 1 | 24 |  |
Vesting of early exercised common stock | 813 |  | 813 |  |
Stock-based compensation | 22,891 |  | 22,891 |  |
Net loss | (74,787) |  |  | (74,787) |
Net unrealized gain (loss) on available-for-sale investments | (2,223) |  |  |  | (2,223)
Ending balance (in shares) at Jun. 30, 2022 |  | 143,723,171 |  |  |
Ending balance at Jun. 30, 2022 | 801,949 | $ 144 | 1,871,262 | (1,057,985) | (11,472)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 177,678 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 135 |  | 135 |  |
Vesting of early exercised common stock | 432 |  | 432 |  |
Stock-based compensation | 21,148 |  | 21,148 |  |
Employee stock purchase plan (in shares) |  | 130,739 |  |  |
Employee stock purchase plan | 931 |  | 931 |  |
Net loss | (83,148) |  |  | (83,148) |
Net unrealized gain (loss) on available-for-sale investments | (1,486) |  |  |  | (1,486)
Ending balance (in shares) at Sep. 30, 2022 |  | 144,031,588 |  |  |
Ending balance at Sep. 30, 2022 | $ 739,961 | $ 144 | 1,893,908 | (1,141,133) | (12,958)
Beginning balance (in shares) at Dec. 31, 2022 | 144,438,304 | 144,438,304 |  |  |
Beginning balance at Dec. 31, 2022 | $ 665,870 | $ 144 | 1,911,632 | (1,235,980) | (9,926)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 942,276 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 0 | $ 1 | (1) |  |
Vesting of early exercised common stock | 603 |  | 603 |  |
Stock-based compensation | 18,770 |  | 18,770 |  |
Employee stock purchase plan (in shares) |  | 359,753 |  |  |
Employee stock purchase plan | 1,731 | $ 1 | 1,730 |  |
Net loss | (98,704) |  |  | (98,704) |
Net unrealized gain (loss) on available-for-sale investments | 3,992 |  |  |  | 3,992
Ending balance (in shares) at Mar. 31, 2023 |  | 145,740,333 |  |  |
Ending balance at Mar. 31, 2023 | $ 592,262 | $ 146 | 1,932,734 | (1,334,684) | (5,934)
Beginning balance (in shares) at Dec. 31, 2022 | 144,438,304 | 144,438,304 |  |  |
Beginning balance at Dec. 31, 2022 | $ 665,870 | $ 144 | 1,911,632 | (1,235,980) | (9,926)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Net loss | (238,008) |  |  |  |
Net unrealized gain (loss) on available-for-sale investments | $ 7,515 |  |  |  |
Ending balance (in shares) at Sep. 30, 2023 | 168,175,221 | 168,175,221 |  |  |
Ending balance at Sep. 30, 2023 | $ 583,102 | $ 168 | 2,059,333 | (1,473,988) | (2,411)
Beginning balance (in shares) at Mar. 31, 2023 |  | 145,740,333 |  |  |
Beginning balance at Mar. 31, 2023 | 592,262 | $ 146 | 1,932,734 | (1,334,684) | (5,934)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock from ATM offering, net of commissions and offering costs (in shares) |  | 20,288,330 |  |  |
Issuance of common stock from ATM offering, net of commissions and offering costs | 87,918 | $ 20 | 87,898 |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 1,105,001 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 1,606 | $ 1 | 1,605 |  |
Vesting of early exercised common stock | 432 |  | 432 |  |
Stock-based compensation | 16,594 |  | 16,594 |  |
Net loss | (77,989) |  |  | (77,989) |
Net unrealized gain (loss) on available-for-sale investments | 2,083 |  |  |  | 2,083
Ending balance (in shares) at Jun. 30, 2023 |  | 167,133,664 |  |  |
Ending balance at Jun. 30, 2023 | 622,906 | $ 167 | 2,039,263 | (1,412,673) | (3,851)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Issuance of common stock from ATM offering, net of commissions and offering costs (in shares) |  | 606,235 |  |  |
Issuance of common stock from ATM offering, net of commissions and offering costs | 3,194 | $ 1 | 3,193 |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs (in shares) |  | 204,116 |  |  |
Issuance of common stock upon exercise of stock options and vesting of RSUs | 326 | $ 0 | 326 |  |
Vesting of early exercised common stock | 432 |  | 432 |  |
Stock-based compensation | 15,354 |  | 15,354 |  |
Employee stock purchase plan (in shares) |  | 231,206 |  |  |
Employee stock purchase plan | 765 | $ 0 | 765 |  |
Net loss | (61,315) |  |  | (61,315) |
Net unrealized gain (loss) on available-for-sale investments | $ 1,440 |  |  |  | 1,440
Ending balance (in shares) at Sep. 30, 2023 | 168,175,221 | 168,175,221 |  |  |
Ending balance at Sep. 30, 2023 | $ 583,102 | $ 168 | $ 2,059,333 | $ (1,473,988) | $ (2,411)

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