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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Revenues        
Collaboration revenue - related party $ 43 $ 49 $ 139 $ 196
Operating expenses:        
Research and development 45,977 63,641 188,253 180,968
General and administrative 17,041 18,897 54,449 58,303
Total operating expenses 63,018 82,538 242,702 239,271
Loss from operations (62,975) (82,489) (242,563) (239,075)
Other income (expense), net:        
Interest and other income, net 6,205 1,002 12,042 1,809
Other expenses (4,545) (1,661) (7,487) (519)
Total other income (expense), net 1,660 (659) 4,555 1,290
Net loss (61,315) (83,148) (238,008) (237,785)
Other comprehensive loss:        
Net unrealized gain (loss) on available-for-sale investments 1,440 (1,486) 7,515 (10,391)
Net comprehensive loss $ (59,875) $ (84,634) $ (230,493) $ (248,176)
Net loss per share, basic (in dollars per share) $ (0.37) $ (0.58) $ (1.55) $ (1.67)
Net loss per share, diluted (in dollars per share) $ (0.37) $ (0.58) $ (1.55) $ (1.67)
Weighted-average number of shares used in computing net loss per share, basic (in shares) 167,649,010 143,661,721 153,087,449 142,809,469
Weighted-average number of shares used in computing net loss per share, diluted (in shares) 167,649,010 143,661,721 153,087,449 142,809,469