<SEC-DOCUMENT>0001387131-22-007804.txt : 20220720
<SEC-HEADER>0001387131-22-007804.hdr.sgml : 20220720
<ACCEPTANCE-DATETIME>20220720162253
ACCESSION NUMBER:		0001387131-22-007804
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220720
DATE AS OF CHANGE:		20220720
GROUP MEMBERS:		ATLAS VENTURE ASSOCIATES XII, L.P.
GROUP MEMBERS:		ATLAS VENTURE ASSOCIATES XII, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aerovate Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001798749
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				831377888
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92668
		FILM NUMBER:		221094462

	BUSINESS ADDRESS:	
		STREET 1:		200 BERKELEY STREET
		STREET 2:		FLOOR 18
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		617-443-2400

	MAIL ADDRESS:	
		STREET 1:		200 BERKELEY STREET
		STREET 2:		FLOOR 18
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Atlas Venture Fund XII, L.P.
		CENTRAL INDEX KEY:			0001812049
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		400 TECHNOLOGY SQUARE
		STREET 2:		10TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		857-201-2700

	MAIL ADDRESS:	
		STREET 1:		400 TECHNOLOGY SQUARE
		STREET 2:		10TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>aerovate-sc13da_071522.htm
<DESCRIPTION>AMENDMENT TO FORM SC 13D
<TEXT>
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<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&nbsp; <FONT STYLE="font-size: 10pt"><B>UNITED STATES</B></FONT></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp; <FONT STYLE="font-size: 10pt"><B>SECURITIES AND EXCHANGE COMMISSION</B></FONT></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp; <FONT STYLE="font-size: 10pt"><B>Washington, D.C. 20549</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: center; margin-top: 0pt; margin-bottom: 0pt"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp; <FONT STYLE="font-size: 10pt"><B>SCHEDULE 13D</B></FONT> &nbsp;</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center"><B>Under the Securities Exchange Act of 1934<BR>
(Amendment No. 2 )*</B></P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-bottom: black 0.5pt solid"><B>Aerovate Therapeutics,
Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center">(Name of Issuer)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-bottom: black 1pt solid"><B>Common Stock, par
value $0.0001 per share</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center">(Title of Class of Securities)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-bottom: black 1pt solid"><B>008064107</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center">(CUSIP Number)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Atlas Venture </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Attention: Ommer Chohan, Chief Financial Officer</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>300 Technology Square, 8th Floor </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center"><B>Cambridge, MA 02139 USA </B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-bottom: black 1pt solid"><B>(857) 201-2700</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 12pt; text-align: center">(Name, Address and Telephone Number of Person<BR>
Authorized to Receive Notices and Communications)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center; border-bottom: black 1pt solid"><B>July 15, 2022</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">(Date of Event Which Requires Filing of this Statement)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">If the filing person has previously filed a statement on Schedule
13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of &sect;&sect;240.13d-1(e),
240.13d-1(f) or 240.13d-1(g), check the following box. <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in"><B>Note</B>: Schedules filed in paper format shall include a
signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">* The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing
information which would alter disclosures provided in a prior cover page.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">The information required on the remainder of this cover page
shall not be deemed to be &quot;filed&quot; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&quot;Act&quot;) or
otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see
the Notes).</P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 6pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR>
    <TD COLSPAN="6" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">CUSIP No. 008064107</FONT></TD></TR>
  <TR>
    <TD COLSPAN="6" STYLE="padding: 3.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Names of Reporting Persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Atlas Venture Fund XII, L.P.</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD COLSPAN="4" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Check the Appropriate Box if a Member of a Group (See Instructions)</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9746;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">SEC Use Only </FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Source of Funds (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">WC</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Delaware</P></TD></TR>
  <TR>
    <TD COLSPAN="3" ROWSPAN="7" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Number of<BR>
Shares<BR>
Beneficially<BR>
Owned by<BR>
Each<BR>
Reporting<BR>
Person With</FONT></TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,327,909 shares (1)</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,327,909 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,327,909 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">13.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Percent of Class Represented by Amount in Row (11)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">9.5% (2)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">14.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">PN</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 20%">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">As described in Item 5 below, Atlas Venture Fund XII, L.P., a Delaware limited partnership (&#8220;Atlas XII&#8221;), Atlas Venture Associates XII, L.P., a Delaware limited partnership (&#8220;AVA XII LP&#8221;) and Atlas Venture Associates XII, LLC, a Delaware limited liability company (&#8220;AVA XII LLC&#8221; and together with Atlas XII and AVA XII LP, the &#8220;Reporting Persons&#8221;) beneficially own 2,327,909 shares of the Issuer&#8217;s Common Stock held by Atlas XII. AVA XII LP is the general partner of Atlas XII and AVA XII LLC is the general partner of AVA XII LP. Each of AVA XII LP and AVA XII LLC has voting and dispositive power over the shares held by Atlas XII. As such, each of the Reporting Persons share voting and dispositive power with respect to the shares held by Atlas XII.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>






<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(2)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">This percentage is calculated based upon 24,410,393 outstanding shares of Common Stock of the Issuer, as reported in the Issuer&#8217;s Form 10-Q for the quarterly period ended March 31, 2022, filed with the Securities and Exchange Commission on May 16, 2022.</FONT></TD></TR>
  </TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR>
    <TD COLSPAN="6" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">CUSIP No. 008064107</FONT></TD></TR>
  <TR>
    <TD COLSPAN="6" STYLE="padding: 3.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Names of Reporting Persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Atlas Venture Associates XII, L.P.</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD COLSPAN="4" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Check the Appropriate Box if a Member of a Group (See Instructions)</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9746;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">SEC Use Only </FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Source of Funds (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">AF</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Delaware</P></TD></TR>
  <TR>
    <TD COLSPAN="3" ROWSPAN="7" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Number of<BR>
Shares<BR>
Beneficially<BR>
Owned by<BR>
Each<BR>
Reporting<BR>
Person With</FONT></TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 3pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 3pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 3pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">13.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Percent of Class Represented by Amount in Row (11)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">9.6% (2)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">14.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">PN</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 20%">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">As described in Item 5 below, AVA XII LP and AVA XII LLC beneficially own&nbsp;&nbsp;2,343,429 shares of the Issuer&#8217;s Common Stock (2,327,909 shares of the Issuer's Common Stock that are directly held by Atlas XII and 15,520 shares of the Issuer&#8217;s Common Stock that are directly held by AVA XII LP). AVA XII LP is the general partner of Atlas XII and AVA XII LLC is the general partner of AVA XII LP. Each of AVA XII LP and AVA XII LLC has voting and dispositive power over the shares held by Atlas XII. As such, each of the Reporting Persons share voting and dispositive power with respect to the shares held by Atlas XII.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(2)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">This percentage is calculated based upon 24,410,393 outstanding shares of Common Stock of the Issuer, as reported in the Issuer&#8217;s Form 10-Q for the quarterly period ended March 31, 2022, filed with the Securities and Exchange Commission on May 16, 2022.</FONT></TD></TR>
  </TABLE>





<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR>
    <TD COLSPAN="6" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">CUSIP No. 008064107</FONT></TD></TR>
  <TR>
    <TD COLSPAN="6" STYLE="padding: 3.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Names of Reporting Persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Atlas Venture Associates XII, LLC</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD COLSPAN="4" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Check the Appropriate Box if a Member of a Group (See Instructions)</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9744;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&#9746;</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">SEC Use Only </FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Source of Funds (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">AF</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">5.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Delaware</P></TD></TR>
  <TR>
    <TD COLSPAN="3" ROWSPAN="7" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 10pt">Number of<BR>
Shares<BR>
Beneficially<BR>
Owned by<BR>
Each<BR>
Reporting<BR>
Person With</FONT></TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">0</P></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="padding: 3.25pt"><FONT STYLE="font-size: 2pt">&nbsp;</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">2,343,429 shares (1)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt"><FONT STYLE="font-size: 10pt">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions) <FONT STYLE="font-family: Times New Roman, Times, Serif">&#9744;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">13.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Percent of Class Represented by Amount in Row (11)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">9.6% (2)</P></TD></TR>
  <TR>
    <TD STYLE="padding: 3.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 3.25pt"><FONT STYLE="font-size: 10pt">14.</FONT></TD>
    <TD COLSPAN="4" STYLE="border-bottom: black 1pt solid; padding: 3.25pt 3.25pt 4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 7%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 20%">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">As described in Item 5 below, AVA XII LP and AVA XII LLC beneficially own 2,343,429 shares of the Issuer&#8217;s Common Stock (2,327,909 shares of the Issuer's Common Stock that are directly held by Atlas XII and 15,520 shares of the Issuer&#8217;s Common Stock that are directly held by AVA XII LP). AVA XII LP is the general partner of Atlas XII and AVA XII LLC is the general partner of AVA XII LP. Each of AVA XII LP and AVA XII LLC has voting and dispositive power over the shares held by Atlas XII. As such, each of the Reporting Persons share voting and dispositive power with respect to the shares held by Atlas XII.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(2)</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">This percentage is calculated based upon 24,410,393 outstanding shares of Common Stock of the Issuer, as reported in the Issuer&#8217;s Form 10-Q for the quarterly period ended March 31, 2022, filed with the Securities and Exchange Commission on May 16, 2022.</FONT></TD></TR>
  </TABLE>





<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 6pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>INTRODUCTION</B> <B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">This Amendment No. 2 to Schedule 13D (&#8220;Amendment No. 2&#8221;) is being filed as an amendment to the statement on Schedule 13D relating to Common Stock, par value $0.0001 per share (the &#8220;Common Stock&#8221;) of Aerovate Therapeutics, Inc., a Delaware corporation (the &#8220;Issuer&#8221; or &#8220;Aerovate&#8221;), as filed with the Securities and Exchange Commission (the &#8220;SEC&#8221;) on November 5, 2021 (the &#8220;Original Schedule 13D&#8221;), as amended on May 5, 2022 (Amendment No. 1 and together with the Original Schedule 13D, the &#8220;Prior Schedule 13D&#8221;). All capitalized terms not otherwise defined herein shall have the meanings ascribed to the terms in the Prior Schedule 13D. The Prior Schedule 13D is hereby amended and supplemented as follows and, except as expressly amended below, the Prior Schedule 13D remains in full force and effect. <B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>&nbsp;</B></P>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 35.45pt; text-align: left"><FONT STYLE="font-size: 10pt"><B>Item 4. </B></FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt"><B>Purpose of Transaction</B></FONT></TD>
</TR></TABLE>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">Item 4 of the Prior Schedule 13D is hereby amended
and supplemented by adding the following paragraph at the end of Item 4:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">On July 15, 2022, Atlas XII made a pro rata in-kind
distribution for no additional consideration of 310,388 shares of Common Stock to its general partner, AVA XII LP, and its limited partners.
Of the shares distributed by Atlas XII, AVA XII LP received an aggregate of 6,208 shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: justify">&nbsp;</P>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 35.45pt; text-align: left"><FONT STYLE="font-size: 10pt"><B>Item 5. </B></FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-size: 10pt"><B>Interest in Securities of
the Issuer</B></FONT></TD>
</TR></TABLE>


<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(a) - (b).</FONT></TD>
    <TD STYLE="padding-left: 3pt"><FONT STYLE="font-size: 10pt">As of the date hereof, Atlas XII is the record owner of 2,327,909 shares of Common Stock. AVA XII LP is the general partner of Atlas XII and AVA XII LLC is the general partner of AVA XII LP. Each of Atlas XII, AVA XII LP and AVA XII LLC has shared voting and dispositive power over the shares held by Atlas XII. As such, each of Atlas XII, AVA XII LP and AVA XII LLC may be deemed to beneficially own the shares held by Atlas XII.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">As of the date hereof, AVA XII LP is the record owner of 15,520
shares of Common Stock. AVA XII LLC is the general partner of AVA XII LP. Each of AVA XII LP and AVA XII LLC has shared voting and dispositive
power over the shares held by AVA XII LP. As such, each of AVA XII LP and AVA XII LLC may be deemed to beneficially own the shares held
by AVA XII LP.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">Collectively, the Reporting Persons may be deemed to beneficially
own 9.6% of the Issuer&#8217;s outstanding Common Stock, which percentage is calculated based upon 24,410,393 outstanding shares of Common
Stock of the Issuer, as reported in the Issuer&#8217;s Form 10-Q for the quarterly period ended March 31, 2022, filed with the Securities
and Exchange Commission on May 16, 2022.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">The Reporting Persons disclaim group membership, and this Schedule
13D shall not be deemed an admission that the Reporting Persons are members of a group for purposes of Section 13 or for any other purposes.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0 0 0 0.6in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(c)</FONT></TD>
    <TD STYLE="padding-left: 3pt"><FONT STYLE="font-size: 10pt">Except as described herein, none of the Reporting Persons have purchased or sold any shares of Common Stock during the past 60 days.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(d)</FONT></TD>
    <TD STYLE="padding-left: 3pt"><FONT STYLE="font-size: 10pt">No other person is known to have the right to receive or the power to direct the receipt of dividends from, or any proceeds from the sale of, the shares of Common Stock beneficially owned by any of the Reporting Persons.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-size: 10pt">(e)</FONT></TD>
    <TD STYLE="padding-left: 3pt"><FONT STYLE="font-size: 10pt">Not applicable.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 0; text-align: center"><B>Signature</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and correct.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">Dated: July 20, 2022</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

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  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt"><B>Atlas Venture Fund XII, L.P.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 0.5in"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Atlas Venture Associates XII, L.P.</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">its</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Atlas Venture Associates XII, LLC</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">its</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 0.5in"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 0.25pt 0.25pt 1pt"><FONT STYLE="font-size: 10pt">/s/ Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Name: Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Title: Chief Financial Officer</FONT></TD>
    </TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt"><B>Atlas Venture Associates XII, L.P.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 0.5in"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Atlas Venture Associates XII, LLC</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">its</FONT></TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 0.5in"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 0.25pt 0.25pt 1pt"><FONT STYLE="font-size: 10pt">/s/ Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Name: Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Title: Chief Financial Officer</FONT></TD>
    </TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt"><B>Atlas Venture Associates XII, LLC</B></FONT></TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 0.5in"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 0.25pt 0.25pt 1pt"><FONT STYLE="font-size: 10pt">/s/ Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Name: Ommer Chohan</FONT></TD>
    </TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt"><FONT STYLE="font-size: 10pt">Title: Chief Financial Officer</FONT></TD>
    </TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: black 1pt solid; padding: 0.25pt 0.95pt 1pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt 0.95pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>ATTENTION</B></FONT></TD>
    <TD STYLE="border-bottom: black 1pt solid; padding: 0.25pt 0.95pt 1pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; padding: 0.25pt 1.7pt 1pt; text-align: center"><FONT STYLE="font-size: 10pt"><B>Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 12pt 0 6pt; text-align: center">&nbsp;</P>

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