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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
Cash flow from operating activities: |  |
Net loss | $ (69,628) | $ (75,521)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 11,311 | 11,906
Depreciation and amortization expense | 282 | 96
Impairment of right-of-use asset | 256 |
Accretion of discounts and amortization of premiums on investments, net | (2,248) | (3,057)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 299 | 483
Other long-term assets | 563 | (110)
Accounts payable | (2,172) | (164)
Accrued and other liabilities | (9,913) | 9,999
Operating lease assets and liabilities, net | (109) | (26)
Other liabilities | 163 | (384)
Net cash used in operating activities | (71,196) | (56,778)
Cash flow from investing activities: |  |
Purchases of short-term investments | (19,683) | (123,982)
Maturities of short-term investments | 75,712 | 136,000
Purchases of property and equipment |  | (142)
Net cash provided by investing activities | 56,029 | 11,876
Cash flow from financing activities: |  |
Proceeds from sale of common stock in connection with ATM, net | 23,942 | 44,888
Payments for offering costs | (307) | (234)
Proceeds from issuance of common stock under ESPP | 308 | 356
Proceeds from issuance of common stock upon exercise of stock options | 1,484 | 986
Net cash provided by financing activities | 25,427 | 45,996
Net increase in cash and cash equivalents | 10,260 | 1,094
Cash and cash equivalents at the beginning of the year | 23,491 | 22,397
Cash and cash equivalents at the end of the period | 33,751 | $ 23,491
Supplemental disclosure of noncash investing and financing activities: |  |
Right-of-use asset obtained in exchange for operating lease liability | $ 206 |

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