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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Revenues:      
Net product sales $ 248,168 $ 227,188 $ 193,118
Total revenues 248,168 227,188 193,118
Operating expenses:      
Cost of goods sold excluding amortization 23,364 24,488 20,508
Research and development 55,577 48,649 43,594
Selling, general and administrative 140,510 129,736 105,751
Intangible asset amortization 1,478 1,505 1,527
Total operating expenses 220,929 204,378 171,380
Income from operations 27,239 22,810 21,738
Other income 4,416 6,218 3,608
Income before income taxes 31,655 29,028 25,346
Provision (benefit) for income taxes 8,318 (86,525) 138
Net income $ 23,337 $ 115,553 $ 25,208
Net income per share:      
Basic (in dollars per share) $ 0.43 $ 2.17 $ 0.50
Diluted (in dollars per share) $ 0.42 $ 2.11 $ 0.48
Weighted average shares outstanding:      
Basic (in shares) 54,427,683 53,137,562 50,859,947
Diluted (in shares) 55,190,802 54,847,060 53,045,257