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Accounts Payable and Accrued Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Payables and Accruals [Abstract]
Compensation and employee benefits	$ 10,951	$ 6,597
Research and development expenses	6,173	5,893
Royalties payable	5,817	5,904
Consulting and other professional fees	5,052	5,376
Operating lease liabilities	2,117	2,147
Milestone obligations under license agreements	350	0
Other	1,049	1,673
Total accounts payable and accrued liabilities	$ 31,509	$ 27,590

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