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Commitments and Contingencies - HETLIOZ - Additional Information (Detail) - USD ($)
$ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended 203 Months Ended
Jan. 31, 2014
Mar. 31, 2015
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2020
HETLIOZ            
Acquisition of intangible assets     $ 0 $ 0 $ 25,000  
HETLIOZ®            
HETLIOZ            
Acquisition of intangible assets $ 8,000       $ 25,000 $ 37,500
Intangible assets capitalized   $ 25,000       $ 33,000
Royalty payment period     10 years      
Royalty payable percentage on net sales     10.00%      
Percentage of future sublicense fees payable to third-party     mid-twenties