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Summary of Significant Accounting Policies - Net Product Sales (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenue from External Customer [Line Items]
Net product sales	$ 46,056	$ 64,390	$ 108,554	$ 124,582
Amount of net product sales recognized related to a change in estimate	4,800
HETLIOZ® net product sales
Revenue from External Customer [Line Items]
Net product sales	21,979	41,188	61,595	78,219
Fanapt® net product sales
Revenue from External Customer [Line Items]
Net product sales	$ 24,077	$ 23,202	$ 46,959	$ 46,363

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Amount of increase (decrease) in revenue recognized for cumulative catch-up adjustment from change in estimate of transaction price which (increases) decreases obligation to transfer good or service to customer for which consideration from customer has been received or is due. Includes, but is not limited to, change in assessment of whether estimate of variable consideration is constrained.

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