-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 I+OmhMy+ADRS8Kehr0ObY2z7GxGo4KiKVY3beW6t7cqdO18nuKWsZQnRPdop2n6G
 fedFNEJjiSfvbf6jlzzyWg==

<SEC-DOCUMENT>0000950123-99-003992.txt : 19990503
<SEC-HEADER>0000950123-99-003992.hdr.sgml : 19990503
ACCESSION NUMBER:		0000950123-99-003992
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	19990426
ITEM INFORMATION:		
FILED AS OF DATE:		19990430

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRATED SURGICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0000894871
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				680232575
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		
		SEC FILE NUMBER:	001-12471
		FILM NUMBER:		99607154

	BUSINESS ADDRESS:	
		STREET 1:		829 W STADIUM LANE
		CITY:			SACRAMENTO
		STATE:			CA
		ZIP:			95834
		BUSINESS PHONE:		9166463487

	MAIL ADDRESS:	
		STREET 1:		829 WEST STADIUM LANE
		CITY:			SACRAMENTO
		STATE:			CA
		ZIP:			95834
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<DESCRIPTION>INTEGRATED SURGICAL SYSTEMS, INC.
<TEXT>

<PAGE>   1
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549


                                -----------------


                                  F O R M 8 - K

                                 CURRENT REPORT

                         Pursuant to Section 13 or 15(d)
                         of the Securities Exchange Act
                                     of 1934


Date of Report (Date of earliest event reported)            April 26, 1999
                                                -------------------------------

                        INTEGRATED SURGICAL SYSTEMS, INC.
               (Exact name of registrant as specified in charter)


          Delaware                     1-12471                 68-0232575
(State or other jurisdiction         (Commission              (IRS Employer
      of incorporation)              File Number)           Identification No.)


1850 Research Park, Davis, California                           95616-4884
(Address of principal executive offices)                        (Zip Code)



Registrant's telephone number, including area code          (530) 792-2600
                                                   -----------------------------


                                       N/A
         (Former name or former address, if changed since last report.)





                                        1

<PAGE>   2



Item 5.       Other Events


         On April 26, 1999, Ramesh C. Trivedi resigned as Chief Executive
Officer, President and a Director of the Registrant.

         The Registrant is actively seeking a Chief Executive Officer.

         The Board of Directors has appointed a committee of James C. McGroddy,
John N. Kapoor and Gerald D. Knudson to assist management until a full time
chief executive officer is hired. In the interim, the Registrant has agreed in
principle to engage Dr. Trivedi as a consultant to assist the Registrant in the
transition period.


                                        2

<PAGE>   3



                                   SIGNATURES

                  Pursuant to the requirements of the Securities Exchange Act of
1934, the Registrant has duly caused this report to be signed on its behalf by
the undersigned thereunto duly authorized.


                                                INTEGRATED SURGICAL SYSTEMS,
                                                INC.


Dated:   April 28, 1999                         By:  /s/ Mark W. Winn
         Davis, California                           -----------------------
                                                     Mark W. Winn          
                                                     Chief Financial Officer



                                        3

</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
