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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001000096-03-000120.txt : 20030319
<SEC-HEADER>0001000096-03-000120.hdr.sgml : 20030319
<ACCEPTANCE-DATETIME>20030318173202
ACCESSION NUMBER:		0001000096-03-000120
CONFORMED SUBMISSION TYPE:	RW
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20030319

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRATED SURGICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0000894871
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				680232575
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		RW
		SEC ACT:		
		SEC FILE NUMBER:	333-51412
		FILM NUMBER:		03608280

	BUSINESS ADDRESS:	
		STREET 1:		1850 RESEARCH PARK DR
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
		BUSINESS PHONE:		5307922600

	MAIL ADDRESS:	
		STREET 1:		1850 RESEARCH PARK
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
</SEC-HEADER>
<DOCUMENT>
<TYPE>RW
<SEQUENCE>1
<FILENAME>integratedrw.txt
<DESCRIPTION>REGISTRATION WITHDRAWAL
<TEXT>




                        INTEGRATED SURGICAL SYSTEMS, INC.
                            1850 Research Park Drive
                                 Davis, CA 95616
                                 (530) 792-2657

                                 March 17, 2003

VIA EDGAR TRANSMISSION
Securities and Exchange Commission
450 Fifth Street, NW
Washington, D.C. 20549

         Re:      Registration Statement on Form S-3
                  Registration No. 333-51412
                  Application to Withdraw Registration Statement

Ladies and Gentlemen:

     Pursuant to Rule 477 promulgated under the Securities Act of 1933, as
amended (the "1933 Act"), submitted electronically via the EDGAR system,
Integrated Surgical Systems, Inc., a Delaware corporation (the "Company"),
hereby requests the withdrawal of the Company's Registration Statement on Form
S-3 (Registration No.:333-51412) filed with the Securities and Exchange
Commission (the "SEC") on December 7, 2000 (the "Registration Statement").

     The Company has determined that market conditions since that filing have
not been favorable for such an offering and therefore the offering should not
proceed. No securities were sold in connection with the Registration Statement.
The Company respectfully requests, that in accordance with the provisions of
Rule 477(a) under the 1933 Act, the SEC issue an order granting the desired
withdrawal of the Registration Statement.

     If you have any questions or comments with respect to this withdrawal
request, please contact either the Company's counsel, Jack Becker, Esq., of Snow
Becker Krauss P.C., at 605 Third Avenue, New York, New York 10158 (Telephone:
212-455-0400) or the undersigned, at the address or telephone number set forth
above.

                                            Very truly yours,

                                            Integrated Surgical Systems, Inc.

                                            By: /s/ Ramesh C. Trivedi
                                                --------------------------------
                                                    Ramesh C. Trivedi, President



</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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