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<SEC-DOCUMENT>0001000096-04-000286.txt : 20040518
<SEC-HEADER>0001000096-04-000286.hdr.sgml : 20040518
<ACCEPTANCE-DATETIME>20040518115125
ACCESSION NUMBER:		0001000096-04-000286
CONFORMED SUBMISSION TYPE:	NT 10-Q
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040331
FILED AS OF DATE:		20040518
EFFECTIVENESS DATE:		20040518

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRATED SURGICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0000894871
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				680232575
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		NT 10-Q
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-12471
		FILM NUMBER:		04815205

	BUSINESS ADDRESS:	
		STREET 1:		1850 RESEARCH PARK DR
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
		BUSINESS PHONE:		5307922600

	MAIL ADDRESS:	
		STREET 1:		1850 RESEARCH PARK
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
</SEC-HEADER>
<DOCUMENT>
<TYPE>NT 10-Q
<SEQUENCE>1
<FILENAME>iss12b25.txt
<DESCRIPTION>FORM 12B25
<TEXT>


                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 12b-25
                           NOTIFICATION OF LATE FILING

                                                       SEC FILE NUMBER: 1-12471
                                                     CUSIP NUMBER: [458124 10 8]

[  ] Form 10-K   [   ] Form 20-F   [   ] Form 11-K   [ X ] Form 10-Q
[  ] Form N-SAR  [   ] Form N-CSR
                        For Period Ended: March 31, 2004

   [   ] Transition Report on Form 10-K     [   ] Transition Report on Form 20-F
   [   ] Transition Report on Form 11-K     [   ] Transition Report on Form 10-Q
   [   ] Transition Report on Form N-SAR
                        For the Transition Period Ended:

      Nothing in this form shall be construed to imply that the Commission
                 has verified any information contained herein.

If the notification relates to a portion of the filing checked above, identify
the Item(s) to which the notification relates: Not applicable

PART I - REGISTRANT INFORMATION

Full Name of Registrant: Integrated Surgical Systems, Inc.
Former Name if Applicable:  Not Applicable
Address of Principal Executive Office: 1850 Research Drive
                                       Davis, California, 95616

PART II - RULES 12b-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed.

[ X [     (a)  The reasons described in reasonable detail in Part III of this
               form could not be eliminated without unreasonable effort or
               expense;
          (b)  The subject annual report, semi-annual report, transition report
               on Form 10-K, Form 20-F, Form 11-K, Form N-SAR or Form N-CSR, or
               portion thereof, will be filed on or before the fifteenth
               calendar day following the prescribed due date; or the subject
               quarterly report or transition report on Form 10-Q, or portion
               thereof, will be filed on or before the fifth calendar day
               following the prescribed due date; and
          (c)  The accountant's statement or other exhibit required by Rule
               12b-25(c) has been attached if applicable.

<PAGE>


PART III - NARRATIVE

State below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q,
N-SAR, N-CSR or the transition report or portion thereof, could not be filed
within the prescribed period.

         On January 21, 2004, the Audit Committee of the Board of Directors of
         the Registrant appointed Macias, Gini & Company, LLP as its new
         independent auditor to audit the financial statements of the Registrant
         for the year ended December 31, 2003.

         On September 30, 2003 the Registrant's wholly-owned French subsidiary
         ("Subsidiary") was placed under the control and management of a French
         administrator due to its financial condition. During the fourth quarter
         the administrator caused the Subsidiary's operations to cease and its
         assets to be sold. Certain financial records of the Subsidiary remain
         under the control of the administrator and have not been made available
         to the registrant which, along with the timing of the appointment of
         the new independent auditor, has caused a delay in the ability of the
         Registrant's independent auditor to complete the audit of the
         registrant's financial statements for the year ended December 31, 2003.
         As a result, the Company has been unable to finalize its financial
         statements for the quarter ended March 31, 2004.

         For such reasons, the subject Form 10-QSB could not be filed within the
prescribed period.

PART IV - OTHER INFORMATION

(1)      Name and telephone number of person to contact in regard to this
         notification: Charles J. Novak, Chief Financial Officer: (530) 792-2600

(2)      Have all other periodic reports required under Section 13 or 15(d) of
         the Securities Exchange Act of 1934 or Section 30 of the Investment
         Company Act of 1940 during the preceding 12 months or for such shorter
         period that the registrant was required to file such report(s) been
         filed? If the answer is no, identify report(s). [ ] Yes [ X ] No

(3)      Is it anticipated that any significant change in results of operations
         from the corresponding period for the last fiscal year will be
         reflected by the earnings statements to be included in the subject
         report or portion thereof? [ ] Yes [ X ] No If so, attach an
         explanation of the anticipated change, both narratively and
         quantitatively, and, if appropriate, state the reasons why a reasonable
         estimate of the results cannot be made.


Integrated Surgical Systems, Inc. has caused this notification to be signed on
its behalf by the undersigned thereunto duly authorized.

Date: May 18, 2004                  Integrated Surgical Systems, Inc.


                                    By:   /s/  Ramesh C. Trivedi
                                          --------------------------------------
                                               Ramesh C. Trivedi, President

</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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