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<SEC-DOCUMENT>0001050502-04-000548.txt : 20041124
<SEC-HEADER>0001050502-04-000548.hdr.sgml : 20041124
<ACCEPTANCE-DATETIME>20041124142055
ACCESSION NUMBER:		0001050502-04-000548
CONFORMED SUBMISSION TYPE:	10QSB
PUBLIC DOCUMENT COUNT:		8
CONFORMED PERIOD OF REPORT:	20040630
FILED AS OF DATE:		20041124
DATE AS OF CHANGE:		20041124

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRATED SURGICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0000894871
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				680232575
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		10QSB
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-12471
		FILM NUMBER:		041166650

	BUSINESS ADDRESS:	
		STREET 1:		1850 RESEARCH PARK DR
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
		BUSINESS PHONE:		5307922600

	MAIL ADDRESS:	
		STREET 1:		1850 RESEARCH PARK
		CITY:			DAVIS
		STATE:			CA
		ZIP:			95616-4884
</SEC-HEADER>
<DOCUMENT>
<TYPE>10QSB
<SEQUENCE>1
<FILENAME>iss604.txt
<DESCRIPTION>10QSB
<TEXT>

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549
                                   FORM 10-QSB

[X]  Quarterly Report under Section 13 or 15(d) of the Securities Exchange Act
     of 1934 For the quarterly period ended June 30, 2004

[ ]  Transition Report under Section 13 or 15(d) of the Securities Exchange
     Act of 1934

               For the transition period from _______ to ________

                         Commission file number: 1-12471


                        INTEGRATED SURGICAL SYSTEMS, INC.
                        ---------------------------------
        (Exact name of small business issuer as specified in its charter)

                   Delaware                           68-0232575
                   --------                           ----------
       (State or other jurisdiction of     (IRS Employer Identification No.)
       incorporation or organization)

             1850 Research Park Drive, Davis, California 95616-4884
             ------------------------------------------------------
                    (Address of principal executive offices)

                                 (530) 792-2600
                                 --------------
                           (Issuer's telephone number)

                                       N/A
                                       ---
              (Former name, former address and formal fiscal year,
                          if changed since last report)

Check whether the issuer (1) filed all reports required to be filed by Section
13 or 15(d) of the Securities Exchange Act of 1934 during the past 12 months (or
for such shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days.
Yes [ ] No [ X ]

State the number of shares outstanding of each of the issuer's classes of common
equity, as of the latest practicable date: The number of shares of the issuer's
common stock outstanding as of November 15, 2004 was 45,084,089

Transitional Small Business Disclosure Format: Yes [ ] No [ X ]

<PAGE>
<TABLE>
<CAPTION>

                               Integrated Surgical Systems, Inc.
                                          Form 10-QSB
                              For the quarter ended June 30, 2004
                                       Table of Contents



                                                                                             Page
Part I. Financial Information
<S>                                                                                           <C>
         Item 1.    Financial Statements

                    Condensed Consolidated Balance Sheet (Unaudited) at June 30, 2004          3

                    Condensed Consolidated Statements of Operations (Unaudited) for the
                    three months ended June 30, 2004 and 2003                                  4

                    Condensed Consolidated Statements of Operations (Unaudited) for the
                    six months ended June 30, 2004 and 2003                                    5

                    Condensed Consolidated Statements of Cash Flows (Unaudited) for the
                    six months ended June 30, 2004 and 2003                                    6

                    Notes to Condensed Consolidated Financial Statements (Unaudited)           7

         Item 2.    Management's Discussion and Analysis                                      10

         Item 3.    Controls and Procedures                                                   15

Part II. Other Information

         Item 1.    Legal Proceedings                                                         16

         Item 2.    Changes in Securities                                                     16

         Item 3.    Changes in and Disagreement with Accountants                              16

         Item 4.    Submission of Matters to a Vote of Security Holders                       16

         Item 5.    Other Information                                                         16

         Item 6.    Exhibits and Reports on Form 8-K                                          16

Signature                                                                                     17

Certifications


                                               2
<PAGE>

Part I. Financial Information

     Item 1. Financial Statements (unaudited)


                              Integrated Surgical Systems, Inc.
                            Condensed Consolidated Balance Sheet
                                        June 30, 2004
                                         (Unaudited)

Assets
Current assets:
     Cash                                                                       $        634
     Accounts receivable                                                             121,419
     Inventories                                                                     527,487
     Other current assets                                                            107,800
                                                                                ------------
Total current assets                                                                 757,340

Property and equipment, net                                                           21,332
                                                                                ------------
                                                                                $    778,672
                                                                                ============


Liabilities and stockholders' deficit
Current liabilities:
     Accounts payable                                                           $  2,333,183
     Accrued payroll and related expense                                           1,417,536
     Accrued liabilities                                                             331,003
     Unearned income                                                               2,335,292
     Other current liabilities                                                       280,533
                                                                                ------------
Total current liabilities                                                          6,697,547

Commitments and contingencies

Convertible preferred stock, $0.01 par value, 1,000,000 shares authorized;
     168 shares issued and outstanding ($168,496 aggregate liquidation value)        168,496

Stockholders' deficit:
     Common stock, $0.01 par value, 100,000,000 shares authorized;
         44,936,966 shares issued and outstanding                                    449,370
     Additional paid-in capital                                                   61,906,740
     Accumulated deficit                                                         (68,443,481)
                                                                                ------------
Total stockholders' deficit                                                       (6,087,371)
                                                                                ------------
                                                                                $    778,672
                                                                                ============



See accompanying notes.

                                              3
<PAGE>

                              Integrated Surgical Systems, Inc.
                       Condensed Consolidated Statements of Operations
                                         (Unaudited)



                                                                Three months ended June 30,
                                                                ----------------------------
                                                                    2004            2003
                                                                ------------    ------------
Net revenue                                                     $    467,072    $  1,941,194
Cost of revenue                                                      263,330       1,469,206
                                                                ------------    ------------
                                                                     203,742         471,988
Operating expenses:
     Selling, general and administrative                             327,262         592,420
     Research and development                                        331,002         288,143
                                                                ------------    ------------
                                                                     658,264         880,563
                                                                ------------    ------------
Operating loss                                                      (454,522)       (408,575)

Other income (expense), net:                                          (1,113)         53,738
                                                                ------------    ------------
Net loss                                                        $   (455,635)   $   (354,837)
                                                                ============    ============


Basic and diluted net loss per common share                     $      (0.01)   $      (0.01)
                                                                ============    ============

Shares used in computing basic and diluted net loss per share     44,880,918      42,571,876
                                                                ============    ============



See accompanying notes.



                                              4
<PAGE>

                              Integrated Surgical Systems, Inc.
                       Condensed Consolidated Statements of Operations
                                         (Unaudited)



                                                                  Six months ended June 30,
                                                                ----------------------------
                                                                    2004            2003
                                                                ------------    ------------
Net revenue                                                     $  1,249,873    $  4,961,796
Cost of revenue                                                      558,430       3,136,137
                                                                ------------    ------------
                                                                     691,443       1,825,659
Operating expenses:
     Selling, general and administrative                             683,144       1,370,983
     Research and development                                        718,483         736,412
                                                                ------------    ------------
                                                                   1,401,627       2,107,395
                                                                ------------    ------------
Operating loss                                                      (710,184)       (281,736)

Other income (expense), net:                                          (2,088)         96,890
                                                                ------------    ------------
Net loss                                                        $   (712,272)   $   (184,846)
                                                                ============    ============


Basic and diluted net loss per common share                     $      (0.02)   $      (0.00)
                                                                ============    ============

Shares used in computing basic and diluted net loss per share     44,874,138      42,276,812
                                                                ============    ============



See accompanying notes.



                                              5
<PAGE>

                               Integrated Surgical Systems, Inc.
                   Condensed Consolidated Statements Cash Flows (Unaudited)



                                                                      Six months ended June 30,
                                                                      --------------------------
                                                                          2004           2003
                                                                      -----------    -----------
Cash flows from operating activities:
Net loss                                                              $  (712,272)   $  (184,846)
Adjustments to reconcile net loss to net cash provided by (used in)
 operating activities:
     Depreciation                                                          13,665        147,244
     Non-cash compensation charge                                           3,800           --
     Changes in operating assets and liabilities:
        Accounts receivable                                               (10,663)       783,067
        Inventories                                                       (40,533)       425,907
        Other current assets                                                5,109         36,035
        Accounts payable                                                  370,334        111,255
        Accrued payroll and related expenses                              536,089        285,819
        Accrued liabilities                                               (23,913)        28,189
        Unearned income                                                  (508,881)    (1,548,762)
        Other current liabilities                                         103,446         28,899
                                                                      -----------    -----------
Net cash provided by (used in) operating activities                      (263,819)       112,807

Cash flows from investing activities:
Purchases of property and equipment                                          --          (17,708)
                                                                      -----------    -----------
Net cash provided by (used in) investing activities                          --          (17,708)

Cash flows from financing activities:
Proceeds from exercise of stock options                                       945           --
Proceeds from officer advances and deferrals of salaries and
    unreimbursed travel expenses                                          180,799        339,847
Payments on officer advances, deferred salaries and
    unreimbursed travel expenses                                          (60,200)      (140,962)
                                                                      -----------    -----------
Net cash provided by financing activities                                 121,544        198,885

Effect of exchange rate changes on cash                                      --          (88,115)
                                                                      -----------    -----------
Net increase (decrease) in cash                                          (142,275)       205,869
Cash at beginning of period                                               142,909         82,069
                                                                      -----------    -----------
Cash at end of period                                                 $       634    $   287,938
                                                                      ===========    ===========

Supplemental disclosure of non-cash investing activity:
Conversion of preferred stock                                         $      --      $    32,000



See accompanying notes.

                                                6
</TABLE>
<PAGE>

                        Integrated Surgical Systems, Inc.
        Notes to Condensed Consolidated Financial Statements (unaudited)
                                  June 30, 2004

1. Basis of presentation

The condensed consolidated financial statements have been prepared by Integrated
Surgical Systems, Inc. (the "Company") pursuant to the rules and regulations of
the Securities and Exchange Commission ("SEC"). Certain information and footnote
disclosures normally included in annual financial statements prepared in
accordance with accounting principles generally accepted in the United States of
America have been condensed or omitted as permitted by such rules and
regulations. While the interim financial information contained in this filing is
unaudited, such financial statements reflect all adjustments, consisting only of
normal recurring adjustments, which the Company considers necessary for a fair
presentation. The results for interim periods are not necessarily indicative of
the results to be expected for the entire fiscal year. These financial
statements should be read in conjunction with the consolidated financial
statements and notes thereto included in the Company's Annual Report on Form
10-KSB for the fiscal period ended December 31, 2003.

The preparation of financial statements in conformity with accounting principles
generally accepted in the United States of America requires management to make
estimates and assumptions that affect the reported amounts and related
disclosures. Actual results could differ from those estimates.

2. Results of Operations and Management's Plan

The accompanying condensed consolidated financial statements have been prepared
on a going concern basis, which contemplates the realization of assets and the
satisfaction of liabilities in the normal course of business. As shown in the
accompanying condensed consolidated financial statements for the six-month
period ended June 30, 2004, the Company incurred a net loss for such six-month
period of $712,272 and had an accumulated deficit as of June 30, 2004 of
$68,443,481. For the year ended December 31, 2003, the Company incurred a net
loss of $3,250,219 and had an accumulated deficit at December 31, 2003 of
$67,731,209. The report of independent auditors on the Company's December 31,
2003 consolidated financial statements includes an explanatory paragraph
indicating there is substantial doubt about the Company's ability to continue as
a going concern. The Company believes that it has a plan to address these issues
and enable the Company to continue operating through June 30, 2005. This plan
includes obtaining additional equity or debt financing, increasing product sales
in existing markets, increasing sales of system upgrades, and further reductions
in operating expenses as necessary (see note 5). Although the Company believes
that the plan will be realized, there is no assurance that these events will
occur. In the event that the Company is unsuccessful, it is possible that it
will cease operations and/or seek bankruptcy protection. The June 30, 2004
condensed consolidated financial statements do not include any adjustments to
reflect the uncertainties related to the recoverability and classification of
assets or the amounts and classification of liabilities that may result from an
inability of the Company to continue as a going concern.

3. Inventories

At June 30, 2004, the components of inventories were:

             Raw materials                                 $120,513
             Work-in-process                                233,726
             Finished goods                                 124,608
             Deferred product development contract costs     48,640
                                                           --------
                                                           $527,487
                                                           ========

                                        7
<PAGE>

4. Warranty and Service Contracts

The Company offers a one-year warranty for parts and labor on all ROBODOC(R)
systems generally commencing upon the completion of training and installation.
In most cases, the Company's customers purchase a service contract, which
includes warranty coverage (parts and labor), unspecified product maintenance
updates, customer support services and various consumables required during
surgical procedures. Customers not covered by warranties or service contracts
are billed on a time and materials basis for service, and on a per unit basis
for products. At June 30, 2004, the Company had no recorded warranty liability
as all systems within the one-year warranty period were covered by service
contracts. Revenue related to maintenance and service contracts is recognized
ratably over the duration of the contract.

5. Securities Purchase Agreement

To obtain funding for the Company's ongoing operations, the Company entered into
a securities purchase agreement (the "Agreement") with an accredited investor on
June 15, 2004 with respect to the sale by the Company for aggregate
consideration of $150,000 of (i) a convertible debenture in the principal amount
of $150,000 and (ii) warrants to purchase 1,500,000 shares of Company common
stock. The Company is obligated to register under the Securities Act for resale
by the investor the common stock underlying the debenture and warrants. The
investor provided the Company with a $200,000 consideration as follows:

     o    $100,000 was disbursed to the Company on June 15, 2004;

     o    $50,000 was disbursed to the Company on October 19, 2004; and

     o    $50,000 has been retained for disbursement to various professionals in
          payment for services to be provided to the Company.

The convertible debenture bears interest at 6 3/4%, matures two years from the
date of issuance, and is convertible into Company common stock, at the
investor's option. The convertible debenture is convertible into the number of
shares of Company common stock equal to the principal amount of the debenture
being converted multiplied by 11, less the product of the conversion factor
multiplied by ten times the dollar principal amount of the debenture being
converted. The conversion factor for the convertible debenture is the lesser of
(i) $0.25 or (ii) eighty percent of the average of the five lowest volume
weighted average prices during the twenty (20) trading days prior to the
conversion. Accordingly, there is in fact no limit on the number of shares into
which the debenture may be converted. In addition, the investor is obligated to
proportionately exercise, concurrently with the submission of a conversion
notice by the selling stockholder, the warrants. The warrants are exercisable
into 1,500,000 shares of common stock at an exercise price of $1.00 per share.

The investor has contractually agreed to restrict its ability to convert or
exercise its warrants and receive shares of Company common stock such that the
number of shares of common stock held by it and its affiliates after such
conversion and exercise does not exceed 4.9% of the then issued and outstanding
shares of Company common stock.

The issuance of more than 51.5 million shares of common stock pursuant to this
agreement would require the Company to issue shares of common stock in excess of
the Company's authorized capital. The Company intends to seek stockholders
approval to increase the Company's current authorized common stock from
100,000,000 to 300,000,000 shares. Such solicitation will be made pursuant to a
proxy statement conforming to the rules and regulations of the Securities and
Exchange Commission. This Quarterly Report on Form 10-QSB should not be
considered, in any manner, a solicitation for voting in favor of such an
increase in authorized stock.

The issuance of the convertible debenture and warrants to the investor is
contingent upon stockholder approval of the increase in the Company's authorized
common stock. If such approval is not received, the Agreement will terminate and
the Company will be obligated to repay the proceeds received. As a result, the
Company recorded such proceeds in other current liabilities.

                                       8
<PAGE>

6.       Stockholders' equity

During the six-month period ended June 30, 2004, 29,608 shares of common stock
were issued as a result of employees exercising stock options at exercise prices
ranging from $0.025 to $0.06 per share. The Company also issued 40,000 shares of
its common stock at $ 0.095 per share as payment for services rendered.

7. Stock-Based Compensation

The Company uses the intrinsic value method in accounting for its employee stock
options in accordance with Accounting Principles Board Opinion No. 25,
"Accounting for Stock Issued to Employees." Under the intrinsic value method,
when the exercise price of employee stock option equals or exceeds the market
price of the underlying stock on the date of grant, no compensation expense is
recognized. Stock option awards which are granted at less than fair market value
result in the recognition of deferred compensation. Deferred compensation is
shown as a reduction of stockholders' equity and is amortized to operating
expenses over the vesting period of the stock award. The Company had no deferred
compensation at June 30, 2004.

Statement of Financial Accounting Standards No. 148, "Accounting for Stock-Based
Compensation-Transition and Disclosure of an Amendment of SFAS No. 123" and
Statement of Financial Accounting Standards No. 123 ("SFAS No. 123"),
"Accounting for Stock-Based Compensation," require the disclosure of certain
information as if the Company had adopted the fair value provisions of SFAS No.
123. The table below illustrates the effect on net loss and net loss per share
had the Company adopted the fair value provisions of SFAS No. 123 using the
following assumptions for the three months and six months ended June 30, 2004
and 2003, respectively: risk-free interest rates of 3.0% and 3.0%; volatility
factors of the expected market price of the common stock of 1.004 and 0.950; and
an expected life of the option of 4 years.
<TABLE>
<CAPTION>

                                       Three months ended June 30,   Six months ended June 30,
                                       ---------------------------   -------------------------
                                             2004         2003           2004         2003
                                          ---------    ---------      ---------    ---------
<S>                                       <C>          <C>            <C>          <C>
Net loss                                  $(455,635)   $(354,837)     $(712,272)   $(184,846)
Add:  stock-based employee compensation
         included in reported net loss         --           --             --           --
Less:  stock-based employee
         compensation expense,
         determined under fair value
         methods for all awards              (3,443)     (34,814)       (11,902)     (60,948)
                                          ---------    ---------      ---------    ---------
Pro forma net loss                        $(459,078)   $(389,651)     $(724,174)   $(245,794)
                                          =========    =========      =========    =========
Loss per share:
  Basic and diluted loss per share        $   (0.01)   $   (0.01)     $   (0.02)   $   (0.00)


8. Net loss per share

Basic net loss per share is computed by dividing the net loss available to
common stockholders for the period by the weighted average number of common
shares outstanding during the period. Diluted net loss per share is computed by
dividing the net loss for the period by the weighted average number of common
and potential common shares outstanding during the period if their effect is
dilutive. Potential common shares are comprised of outstanding employee stock
options, outstanding warrants and outstanding preferred stock issuable upon the
exercise of the stock option, warrant or preferred stock. The potential common
shares issuable under stock options, warrants and preferred stock to purchase
common shares have been excluded for the three and six month periods ending June
30, 2004 and 2003 respectively, from the diluted calculation because the effect
of such shares would have been anti-dilutive.

                                       9
<PAGE>

At June 30, 2004, the Company had outstanding options to purchase 2,379,234
shares of common stock (with exercise prices ranging from $0.025 to $8.50 per
share), 2,991,479 outstanding warrants to purchase 2,991,479 shares of common
stock (with exercise prices from $0.06 to $1.02 per share), and 3,510,333 shares
of common stock issuable upon conversion of Series G convertible preferred
stock. The exercise price and the ultimate number of shares of common stock
issuable upon exercise of outstanding options and warrants and conversion of the
Series G convertible preferred stock are subject to adjustments based upon the
occurrence of certain future events.

9. Accumulated Other Comprehensive Loss

                               Three months ended June 30,   Six months ended June 30,
                               ---------------------------   -------------------------
                                     2004         2003            2004         2003
                                  ---------    ---------       ---------    ---------

Net loss                          $(455,635)   $(354,837)      $(712,272)   $(184,846)

Other comprehensive loss:

   Foreign currency translation        --        (36,559)           --        (58,275)
                                  ---------    ---------       ---------    ---------
Comprehensive loss                $(455,635)   $(391,396)      $(712,272)   $(243,121)
                                  =========    =========       =========    =========
</TABLE>

10. Contingencies

The Company is subject to legal proceedings and claims that arise in the normal
course of business. The Company cannot assure that it would prevail in such
matters nor can it assure that the Company would have sufficient funds available
to satisfy any adverse judgement. Due to the inherent uncertainties of
litigation, were there any such matters, the Company would not be able to
accurately predict their ultimate outcome. As of June 30, 2004, there were no
current proceedings or litigation involving the Company that the Company
believes, if judgement were rendered against the Company, would have a material
adverse impact on its financial position, results of operations or cash flows.

     Item 2. Management's Discussion and Analysis

The discussion in this Quarterly Report on Form 10-QSB contains forward-looking
statements that have been made pursuant to the provisions of the Private
Securities Litigation Reform Act of 1995. Such forward-looking statements are
based on current expectations, estimates and projections about the software
industry and certain assumptions made by the Company's management. Words such as
"anticipates," "expects," "intends," "plans," "believes," "seeks," "estimates,"
"could," "would," "may" and variations of such words and similar expressions are
intended to identify such forward-looking statements. These statements are not
guarantees of future performance and are subject to certain risks, uncertainties
and assumptions that are difficult to predict; therefore, actual results may
differ materially from those expressed or forecasted in any such forward-looking
statements. Unless required by law, the Company undertakes no obligation to
update publicly any forward-looking statements, whether as a result of new
information, future events or otherwise. However, readers should carefully
review the risk factors set forth in other reports or documents the Company
files from time to time with the SEC, particularly the Company's Annual Report
on Form 10-KSB, Quarterly Reports on Form 10-QSB and any Current Reports on Form
8-K.

The following discussion should be read in conjunction with the unaudited
Condensed Consolidated Financial Statements and Notes thereto in Part I, Item 1
of this Quarterly Report on Form 10-QSB and with the audited Consolidated
Financial Statements and Notes thereto, together with Management's Discussion
and Analysis of Financial Condition and Results of Operations, which are
included in the Company's Annual Report on Form 10-KSB for the fiscal year ended
December 31, 2003 as filed with the SEC.

                                       10
<PAGE>

Overview

The Company designs, manufactures, sells and services image-directed,
computer-controlled robotic software and hardware products for use in orthopedic
and neurosurgical procedures.

In 1997, the Company acquired a 100% interest in a French company, Innovative
Medical Machines International, S.A. ("ISS-SA"), involved in the manufacturing
and servicing of neurosurgical products.

Under French law, a company whose net assets are less than 50% of its capital
stock may come under the supervision and control of a regional administrative
tribunal. On September 30, 2003 the Tribunal de Commerce (the "Tribunal") in
Lyon, France determined that ISS-SA met the criteria for it to appoint an
administrator to manage the Company's operations. The Tribunal acted after a
hearing in which the Company and ISS-SA discussed the ability of ISS-SA to meet
its obligations over the next four months and the Company's unwillingness to
further fund its operations due to ISS-SA's history of operating losses. The
Tribunal authorized the administrator to manage ISS-SA's operations pending a
review of ISS-SA's operations and cash flow projections. Subsequent to its
appointment, the administrator exercised control over all aspects of ISS-SA's
operations including employee retention, purchasing, sales and inventory
management. As a result, effective with the administrator's appointment, the
Company no longer had access to the assets, personnel or records of ISS-SA.

On October 30, 2003, representatives of the Company met with the Tribunal to
review the status of ISS-SA. At that meeting, the Tribunal determined that
ISS-SA was making progress in improving its financial position and scheduled
another meeting for December 2003. Prior to such meeting, the Tribunal
reevaluated its decision to allow ISS-SA to continue operating and caused the
assets and operations of ISS-SA to be sold, effectively terminating ISS-SA's
operations on December 23, 2003. The Company recorded a loss of $1,516,519 in
connection with the liquidation of the Company's investment in ISS-SA and
closure of the Company's European operation in the fourth quarter of 2003.

The Company's revenue consists of product revenue, product development revenue,
parts and consumables and service revenue.

Product revenue consists of the Company's principal orthopaedic product, the
ROBODOC(R) Surgical Assistant System ("ROBODOC"), which integrates the
ORTHODOC(R) Presurgical Planner ("ORTHODOC") with a computer-controlled robot
for use in joint replacement surgeries. Also included in product revenue for the
first and second quarters of 2003 are sales of the NeuroMate(TM) System
("NeuroMate"), which consists of a computer-controlled robotic arm, head
stabilizer, presurgical planning workstation and proprietary software used to
position and precisely hold critical tools during stereotactic brain surgery.
The Company develops specialized operating software for several implant
manufacturing companies. These implant manufacturers contract with the Company
for the development of particular lines of new prosthesis software to be used
with the ROBODOC system. Fees for these services are recorded as product
development revenue as earned.

The Company offers a one-year warranty for parts and labor on all ROBODOC
systems generally commencing upon the completion of training and installation.
In most cases, the Company's customers purchase a service contract, which
includes warranty coverage (parts and labor), unspecified product maintenance
updates, customer support services and various consumables required during
surgical procedures. Customers not covered by warranties or service contracts
are billed on a time and materials basis for service, and on a per unit basis
for products. Revenue related to maintenance and service contracts is recognized
ratably over the duration of the contract.

Results of Operations

For the three-month period ending June 30, 2004, net revenue decreased
approximately 76% or $1.5 million when compared to the three-month period ended
June 30, 2003. Cost of revenue for the same three-month comparative periods
decreased 82% or $1.2 million which resulted in a decrease in the gross margin
of 57% or $0.3 million. Operating expenses decreased during the three-month
period ending June 30, 2004 compared to the same three-month period of 2003 by
25% or $0.2 million, with an operating loss of approximately $455,000 and net
loss of $456,000 as compared to an operating loss of $409,000 and net loss of

                                       11
<PAGE>

$355,000, respectively, for the same three-month comparative periods. For the
six-month period ending June 30, 2004, net revenue decreased 75% or $3.7 million
when compared to the six-month period ended June 30, 2003. Cost of revenue for
the same six-month comparative periods decreased 82% or $2.6 million which
resulted in a decrease in the gross margin of 62% or $1.1 million. Operating
expenses decreased during the six-month period ending June 30, 2004 compared to
the same six-month period of 2003 by 33% or $0.7 million, with an operating loss
of approximately $710,000 and net loss of approximately $712,000 as compared to
an operating loss of approximately $282,000 and net loss of approximately
$185,000 respectively for the same six-month comparative periods.

Net Revenue

Net revenue of $1.9 million for the second quarter of 2003 decreased to $0.5
million for the second quarter of 2004. This 76% decrease for comparative
quarters is primarily due to the loss of $0.9 million in net revenue generated
by the Company's European operations, that were liquidated during the fourth
quarter of 2003. The remaining reduction in revenue in the second quarter of
2004, when compared to the second quarter of 2003, was primarily the result of a
$450,000 decrease in product development revenue due to decreases in the number
of projects and development activity that the Company's non-European operations
were involved in. During the second quarter ending June 30, 2003 revenue on one
Robodoc and two Neuromates's was recognized while revenue of only one
refurbished Robodoc was recognized during the second quarter ended June 30,
2004.

Net revenue decreased 75% from $5.0 million during the first six-months of 2003
to $1.2 million during the first six months of 2004. The decrease in net revenue
was primarily due to the elimination of $2.6 million in net revenue generated by
the Company's European operations, which were liquidated in December 2003. The
remaining reduction of $1.2 million in revenue in the first six months of 2004,
when compared to the first six months of 2003, was primarily due to a decrease
of $0.9 in product development revenue as a result of decreases in the number of
projects and development activity that the Company's non-European operations
were involved in. During the six-month period ended June 30, 2003 the Company
had recognized revenue on four ROBODOC systems and four NeuroMate systems while
only two ROBODOC systems were sold for the same six-month period of 2004. Both
of the ROBODOC systems in 2004 were previously returned units, which were
recorded in inventory at a zero dollar value, and have a lower average selling
price when resold.

Cost of revenue

Cost of revenue decreased 82% from $1.5 million during the second quarter of
2003 to $0.3 million during the second quarter of 2004. The decrease in cost of
revenue was primarily due to the elimination of $0.7 million in cost of revenue
generated by the Company's European operations, which were liquidated during the
fourth quarter of 2003. The remaining reduction of $0.5 million in cost of
revenue in the second quarter of 2004, when compared to the second quarter of
2003, was primarily the result of the sale of one refurbished unit, and a
reduction in the amount of general and administrative expenses allocated to the
Company's manufacturing activities due to its cost reduction programs. Cost of
revenue for the six-month period ended June 30, 2004 decreased 81% to $0.6
million from $3.1 million for the six-month period ended June 30, 2003. The
decrease in the cost of revenue was primarily due to the elimination of $1.8
million in cost of revenue attributable to the Company's European operations.
The remaining reduction in cost of revenue during the six-month period ending
June 30, 2004, when compared to the cost of revenue for the same period of the
prior year, was primarily due to the decreases in the number of units shipped.

Gross margin increased from approximately 24% for the three-month period ending
June 30, 2003 to 43% for the three-month period ending June 30, 2004 and
increased from 37% for the six-month period ending June 30, 2003 to 55% for the
six-month period ending June 30, 2004. This increase for the three and six-month
periods in 2004 was due to the higher margins the Company enjoyed on the sale of
refurbished units.

Operating expenses

Total operating expenses have continued to decline as a result of the Company's
cost reduction program and the liquidation of its European operations. Selling
and general administrative expenses are comprised of salaries, commissions,
travel expenses and costs associated with trade shows as well as the finance,
legal and human resources departments and professional support fees for these
functions. Selling and general administrative expenses for the three-month
period ending June 30, 2004 decreased approximately 50% to $0.3 million from
$0.6 million for the three-month period ending June 30, 2003. Selling and
general administrative expenses for the six-month period ending June 30, 2004
decreased 50% to $0.7 million from $1.4 million for the six-month period ending
June 30, 2003. The primary factor causing such decreases in selling, general and

                                       12
<PAGE>

administrative expense is the liquidation of the Company's European operations
which accounted for $0.2 million and $0.4 million of the decrease for the three
and six-month periods ended June 30, 2003 respectively. The remaining decrease
in selling and general administrative expense for the three-month period ending
June 30, 2004 is due to a reduction in commission expense resulting from lower
sales volume. In addition to the decrease in commission expense, selling and
general administrative expense decreased in the six-month period as a result of
reduced headcount.

Research and development expenses are comprised of the engineering and related
costs associated with the development of innovative image-directed
computer-controlled robotic products for surgical applications, along with
specialized operating software and hardware systems to support these products,
quality assurance and testing. Research and development expenses increased
approximately 14% to $0.3 million during the three-month period ending June 30,
2004. The increase for the three-month period ended June 30, 2004 is related to
$125,000 in grant funding recorded by the Company as a reduction of research and
development expense during the three-month period ended June 30, 2003. Without
such grant funding, research and development expenses would have decreased by
$82,000 or 20%. After giving effect to the $125,000 in grant funding research
and development expenses for the six-month periods of June 30, 2004 and 2003 on
a comparative basis remained relatively flat. The $125,000, received in April
2003 was the final payment under a grant from the National Institute for
Standards and Technology of the United States Department of Commerce ("NIST").
Under the terms of the NIST grant, the Company was entitled to reimbursement for
certain of the expenses incurred in connection with the development of its
revision hip surgery product. As of December 31, 2003, the Company had received
a cumulative total of approximately $1,221,000 in funding from NIST since 1995.
The Company has recorded the proceeds from the NIST grant as a reduction of its
research and development expenses.

During the three and six month periods ended June 30, 2003, the Company recorded
$53,000 and $97,000 of other income (expense), net, respectively, primarily as
the result of favorable foreign currency exchange rates for that three-month
period and six-month periods respectively. The Company was not affected by
foreign currency exchange rates during the first quarter and second quarter of
2004.

Critical Accounting Policies and Estimates

The preparation of the Company's unaudited condensed consolidated financial
statements requires the Company to make estimates and judgments that affect the
reported amounts of assets, liabilities, revenue and expenses, and related
disclosure of contingent assets and liabilities. On an on-going basis, the
Company evaluates the estimates, including those related to bad debts,
inventories, impairment of assets, warranties, contingencies and litigation. The
Company bases these estimates on historical experience and on other assumptions
believed to be reasonable under the circumstances, the results of which form the
basis for making judgments about the carrying values of assets and liabilities
that are not readily apparent from other sources. The Company's management has
discussed these critical accounting policies with the audit committee of the
Company. Actual results may differ from these estimates under different
assumptions or conditions.

The Company believes the following critical accounting policies affect the
Company's more significant judgments and estimates used in the preparation of
the condensed consolidated financial statements:

     The Company recognizes revenue from sales of its products upon the
     completion of equipment installation and training at the end-user's site,
     except when the sales contract requires formal customer acceptance.
     Equipment sales with contractual customer acceptance provisions are
     recognized as revenue upon written notification of customer acceptance,
     which generally occurs after the completion of installation and training.
     Furthermore, due to business customs in Japan and the interpretation of
     Japanese law, all equipment sales to Japanese customers are recognized
     after customer acceptance, which generally occurs after the completion of
     installation and training. Revenue related to maintenance and service
     contracts is recognized ratably over the duration of the contracts.

                                       13
<PAGE>

     The Company periodically evaluates the need for allowances for doubtful
     accounts for estimated losses resulting from the inability of the Company's
     customers to make required payments. If the financial condition of its
     customers were to deteriorate, resulting in an impairment of their ability
     to make payments, additional allowances may be required.

     Where the Company's products are not covered by separate service
     agreements, the Company reserves against the estimated cost of product
     warranties at the time revenue is recognized. The warranty obligation is
     affected by product failure rates, material usage and service delivery
     costs incurred in correcting a product failure. Should actual product
     failure rates, material usage or service delivery costs differ from these
     estimates, revisions to the estimated warranty liability would be required.

     The Company writes down inventory for estimated obsolescence or
     unmarketable inventory equal to the difference between the cost of
     inventory and the estimated market value based upon assumptions about
     future demand and market conditions. If actual market conditions are less
     favorable than those the Company projected additional inventory write-downs
     may be required.

     Property, plant and equipment are amortized over their useful lives. Useful
     lives are based on estimates of the period that the assets will generate
     revenue. Property and equipment are reviewed for impairment whenever events
     or changes in circumstances indicate that the carrying amount of an asset
     may not be recoverable.

Liquidity and Capital Resources

The cash position of the Company is inadequate and the Company has not yet
identified sources of sufficient cash to assure continuing operations. The
reports of the Company's independent auditors on the 2003 and 2002 consolidated
financial statements included explanatory paragraphs stating that there is
substantial doubt with respect to the Company's ability to continue as a going
concern. The Company has a plan to address these issues, which the Company
believes will enable the Company to continue operations through June 30, 2005.
This plan includes obtaining additional equity or debt financing, increasing
sales of the products in existing markets, increasing sales of system upgrades,
and reducing operating expenses as necessary. Although the Company believes that
the plan will be realized, there is no assurance that these events will occur.
In the event that the Company is unsuccessful, it is possible that the Company
will cease operations or seek bankruptcy protection. The June 30, 2004 condensed
consolidated financial statements do not include any adjustments to reflect the
uncertainties related to the recoverability and classification of assets or the
amounts and classification of liabilities that may result from an inability of
the Company to continue as a going concern.

At June 30, 2004 the Company's "quick ratio" (cash and accounts receivable
divided by current liabilities), a conservative liquidity measure designed to
predict the Company's ability to pay bills, was only 2%. It has been difficult
for the Company to meet obligations, including payroll, as they come due, and
the Company expects this situation to continue through its December 31, 2004
calendar year. Net cash used in operating activities was approximately $264,000
for the six-month period ended June 30, 2004. This primarily resulted from a net
loss of $712,000, an increase in accounts receivable of $11,000, an increase in
inventory of $41,000, and a decrease in unearned income of $509,000 which were
partially offset by increases in accounts payable of $370,000 and an increase in
accrued payroll and related expenses of $536,000 and $103,000 of other current
liabilities.

At June 30, 2004, the Company had amounts due to the executive officers of the
Company of approximately $1,027,000, in the aggregate, in the forms of an
interest bearing advance, deferred salaries and unreimbursed travel expenses. Of
such amounts, $357,000, $276,000 and $93,000 are included in accrued payroll and
related expense and accounts payable and accrued liabilities, respectively, due
to Ramesh C. Trivedi, president and chief executive officer of the Company;
$102,000, $33,000 and $48,000 are included in accrued payroll and related
expense and accounts payable and accrued liabilities, respectively, due to
Leland Witherspoon, vice president of engineering of the Company; $76,000,
$4,000 and $38,000 are included in accrued payroll and related expense, accounts
payable and accrued liabilities, respectively, due to Charles J. Novak, chief
financial officer of the Company.

                                       14
<PAGE>

To obtain funding for the Company's ongoing operations, the Company entered into
a securities purchase agreement (the "Agreement") with an accredited investor on
June 15, 2004 with respect to the sale by the Company for aggregate
consideration of $150,000 of (i) a convertible debenture in the principal amount
of $150,000 and (ii) warrants to purchase 1,500,000 shares of Company common
stock. The Company is obligated to register under the Securities Act for resale
by the investor the common stock underlying the debenture and warrants.

The investor provided the Company with a $200,000 consideration as follows:

     o    $100,000 was disbursed to the Company on June 15, 2004;

     o    $50,000 was disbursed to the Company on October 19, 2004; and

     o    $50,000 has been retained for disbursement to various professionals in
          payment for services to be provided to the Company.

The convertible debenture bears interest at 6 3/4%, matures two years from the
date of issuance, and is convertible into Company common stock, at the
investor's option. The convertible debenture is convertible into the number of
shares of Company common stock equal to the principal amount of the debenture
being converted multiplied by 11, less the product of the conversion factor
multiplied by ten times the dollar principal amount of the debenture being
converted. The conversion factor for the convertible debenture is the lesser of
(i) $0.25 or (ii) eighty percent of the average of the five lowest volume
weighted average prices during the twenty (20) trading days prior to the
conversion. Accordingly, there is in fact no limit on the number of shares into
which the debenture may be converted. In addition, the investor is obligated to
proportionately exercise, concurrently with the submission of a conversion
notice by the selling stockholder, the warrants. The warrants are exercisable
into 1,500,000 shares of common stock at an exercise price of $1.00 per share.

The investor has contractually agreed to restrict its ability to convert or
exercise its warrants and receive shares of Company common stock such that the
number of shares of common stock held by it and its affiliates after such
conversion and exercise does not exceed 4.9% of the then issued and outstanding
shares of Company common stock.

The issuance of more than 51.5 million shares of common stock pursuant to this
agreement would require the Company to issue shares of common stock in excess of
the Company's authorized capital. The Company intends to seek stockholders
approval to increase the Company's current authorized common stock from
100,000,000 to 300,000,000 shares. Such solicitation will be made pursuant to a
proxy statement conforming to the rules and regulations of the Securities and
Exchange Commission. This Quarterly Report on Form 10-QSB should not be
considered, in any manner, a solicitation for voting in favor of such an
increase in authorized stock.

The issuance of the convertible debenture and warrants to the investor is
contingent upon stockholder approval of the increase in the Company's authorized
common stock. If such approval is not received the Agreement will terminate and
the Company will be obligated to repay the proceeds received. As a result, the
Company recorded such proceeds in other current liabilities.

     Item 3. Controls and Procedures

(a) Under the supervision and with the participation of management, including
the Company's President and Chief Executive Officer and Chief Financial Officer,
an evaluation was made of the effectiveness of the Company's disclosure controls
and procedures, as such term is defined under Rule 13a-15(e) promulgated under
the Securities Exchange Act of 1934, as amended. Based upon that evaluation, the
President and Chief Executive Officer and the Chief Financial Officer concluded
that the Company's disclosure controls and procedures were effective as of the
end of the period covered by this quarterly report.

(b) There has been no change in the Company's internal control over financial
reporting during the quarter ended June 30, 2004 that has materially affected,
or is reasonably likely to materially affect, the Company's internal control
over financial reporting.

                                       15
<PAGE>

Part II. Other Information

     Item 1. Legal Proceedings

The Company is subject to legal proceedings and claims that arise in the normal
course of business. The Company cannot assure that it would prevail in such
matters nor can it assure that the Company would have sufficient funds available
to satisfy any adverse judgement. Due to the inherent uncertainties of
litigation, were there any such matters, the Company would not be able to
accurately predict their ultimate outcome. As of June 30, 2004, there were no
current proceedings or litigation involving the Company that the Company
believes if judgement were rendered against the Company, would have a material
adverse impact on its financial position, results of operations or cash flows.

     Item 2. Changes in Securities

During the second quarter of 2004, the Company issued a total of 69,608 shares
of common stock of which 29,608 was issued to former employees upon exercise of
stock options and the other 40,000 was issued to an independent contractor as
payment for services rendered. The issuance of stock to the independent
contractor was recorded as an expense during the second quarter of 2004.

     Item 3. Changes in and Disagreements with Accountants

None.

     Item 4. Submission of Matters to a Vote of Security Holders

None.

     Item 5. Other Information

None.

     Item 6. Exhibits and Reports on Form 8-K

(a)Exhibits

10.1   $150,000, 6 3/4% Convertible Debenture, registered in the name of Golden
       Gate Investors, Inc.
10.2   1,500,000 Warrant Certificate, registered in the name of Golden Gate
       Investors, Inc.
10.3   Securities Purchase Agreement, dated June 15, 2004 between Integrated
       Surgical Systems, Inc. and Golden Gate Investors, Inc.
31.1   Certification Pursuant to Exchange Act Rule 13a-14(a) of Ramesh Trivedi
31.2   Certification Pursuant to Exchange Act Rule 13a-14(a) of Charles Novak
32.1   Certification Pursuant to 18 U.S.C. 1350 of Ramesh Trivedi
32.2   Certification Pursuant to 18 U.S.C. 1350 of Charles Novak

(b)Reports on Form 8-K.

None.



                                       16
<PAGE>



                                    SIGNATURE

In accordance with Section 13 or 15(d) of the Securities Exchange Act of 1934,
the Registrant has caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.


                        INTEGRATED SURGICAL SYSTEMS, INC.


                         By: /s/ CHARLES J. NOVAK
                         -----------------------------------
                         Charles J. Novak
                         (Principal Financial and Accounting Officer)
Dated: November 24, 2004     (Duly Authorized Officer)

















                                       17

</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>iss10-1.txt
<DESCRIPTION>CONVERTIBLE DEBENTURE
<TEXT>
                                  EXHIBIT 10.1



THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE "SECURITIES ACT"), OR THE SECURITIES LAWS OF ANY STATE, AND IS
BEING OFFERED AND SOLD PURSUANT TO AN EXEMPTION FROM THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT AND SUCH LAWS. THIS SECURITY MAY NOT BE SOLD
OR TRANSFERRED EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE
SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT OR SUCH OTHER LAWS.

                          6 3/4 % CONVERTIBLE DEBENTURE

Company: Integrated Surgical Systems, Inc.
Company Address: 1850 Research Park Drive, Davis, CA 95616
Closing Date: June 9, 2004
Maturity Date: June 9, 2006
Principal Amount: $150,000
First Payment Due Date: August 15, 2004

     Integrated Surgical Systems, Inc., a Delaware corporation, and any
successor or resulting corporation by way of merger, consolidation, sale or
exchange of all or substantially all of the assets or otherwise (the "Company"),
for value received, hereby promises to pay to Golden Gate Investors, Inc., a
California corporation (the "Holder") or such other Person (as such term is
hereinafter defined) upon order of the Holder, on the Maturity Date, the
Principal Amount (as such term is hereinafter defined), as such sum may be
adjusted pursuant to Article 3, and to pay interest thereon from June 9, 2004
(the "Closing Date"), monthly in arrears, on the 15th day of each month (each an
"Interest Payment Due Date" and collectively, the "Interest Payment Due Dates"),
commencing on the First Payment Due Date, at the rate of six and three-quarter
percent (6 3/4 %) per annum (the "Debenture Interest Rate"), until the Principal
Amount of this Debenture has been paid in full. All interest payable on the
Principal Amount of this Debenture shall be calculated on the basis of a 360-day
year for the actual number of days elapsed. Payment of interest on this
Debenture shall be in cash or, at the option of the Holder, in shares of Common
Stock of the Company valued at the then applicable Conversion Price (as defined
herein). This Debenture may not be prepaid without the written consent of the
Holder.

                                    ARTICLE 1
                                   DEFINITIONS

     SECTION 1.1 Definitions. The terms defined in this Article whenever used in
this Debenture have the following respective meanings:


                                        1
- -----------------------                                 ------------------------
Initials                                                                Initials

<PAGE>

          (i) "Affiliate" has the meaning ascribed to such term in Rule 12b-2
under the Securities Exchange Act of 1934, as amended.

          (ii) "Bankruptcy Code" means the United States Bankruptcy Code of
1986, as amended (11 U.S.C. ss.ss. 101 et. seq.).

          (iii) "Business Day" means a day other than Saturday, Sunday or any
day on which banks located in the State of California are authorized or
obligated to close.

          (iv) "Capital Shares" means the Common Stock and any other shares of
any other class or series of capital stock, whether now or hereafter authorized
and however designated, which have the right to participate in the distribution
of earnings and assets (upon dissolution, liquidation or winding-up) of the
Company.

          (v) "Common Shares" or "Common Stock" means shares of the Company's
common stock, $0.01 par value per share.

          (vi) "Common Stock Issued at Conversion", when used with reference to
the securities deliverable upon conversion of this Debenture, means all Common
Shares now or hereafter Outstanding and securities of any other class or series
into which this Debenture hereafter shall have been changed or substituted,
whether now or hereafter created and however designated.

          (vii) "Conversion" or "conversion" means the repayment by the Company
of the Principal Amount of this Debenture (and, to the extent the Holder elects
as permitted by Section 3.1, accrued and unpaid interest thereon) by the
delivery of Common Stock on the terms provided in Section 3.2, and "convert,"
"converted," "convertible" and like words shall have a corresponding meaning.

          (viii) "Conversion Date" means any day on which all or any portion of
the Principal Amount of this Debenture is converted in accordance with the
provisions hereof.

          (ix) "Conversion Notice" means a written notice of conversion
substantially in the form annexed hereto as Exhibit A.

          (x) "Conversion Price" on any date of determination means the
applicable price for the conversion of this Debenture into Common Shares on such
day as set forth in Section 3.1(a).

          (xi) "Current Market Price" on any date of determination means the
closing price of a Common Share on such day as reported by the National
Association of Securities Dealers, Inc. Over-The-Counter Bulletion Board (the
"OTCBB"); provided that, if such security is not listed or admitted to trading
on the OTCBB, as reported on the principal national security exchange or
quotation system on which such security is quoted or listed or admitted to
trading, or, if not quoted or listed or admitted to trading on any national
securities exchange or quotation system, the closing bid price of such security
on the over-the-counter market on the day in question as reported by Bloomberg
LP or a similar generally accepted reporting service, as the case may be.

                                        2
<PAGE>

          (xii) "Deadline" means the date that is the 150th day from the Closing
Date.

          (xiii) "Debenture" or "Debentures" means this Convertible Debenture of
the Company or such other convertible debenture(s) exchanged therefor as
provided in Section 2.1.

          (xiv) "Discount Multiplier" has the meaning set forth in Section
3.1(a).

          (xv) "Event of Default" has the meaning set forth in Section 6.1.

          (xvi) "Holder" means Golden Gate Investors, Inc., any successor
thereto, or any Person to whom this Debenture is subsequently transferred in
accordance with the provisions hereof.

          (xvii) "Interest Payment Due Date" has the meaning set forth in the
opening paragraph of this Debenture.

          (xviii) "Market Disruption Event" means any event that results in a
material suspension or limitation of trading of the Common Shares.

          (xix) "Market Price" per Common Share means the lowest price of the
Common Shares during any Trading Day as reported by the OTCBB; provided that, if
such security is not listed or admitted to trading on the OTCBB, as reported on
the principal national security exchange or quotation system on which such
security is quoted or listed or admitted to trading, or, if not quoted or listed
or admitted to trading on any national securities exchange or quotation system,
the lowest price of the Common Shares during any Trading Day on the
over-the-counter market as reported by Bloomberg LP or a similar generally
accepted reporting service, as the case may be.

          (xx) "Maximum Rate" has the meaning set forth in Section 6.4.

          (xxi) "Outstanding" when used with reference to Common Shares or
Capital Shares (collectively, "Shares") means, on any date of determination, all
issued and outstanding Shares, and includes all such Shares issuable in respect
of outstanding scrip or any certificates representing fractional interests in
such Shares; provided, however, that any such Shares directly or indirectly
owned or held by or for the account of the Company or any Subsidiary of the
Company shall not be deemed "Outstanding" for purposes hereof.

          (xxii) "Person" means an individual, a corporation, a partnership, an
association, a limited liability company, an unincorporated business
organization, a trust or other entity or organization, and any government or
political subdivision or any agency or instrumentality thereof.

                                       3
<PAGE>

          (xxiii) "Principal Amount" means, for any date of calculation, the
principal sum set forth in the first paragraph of this Debenture (but only such
principal amount as to which the Holder has (a) actually advanced pursuant to
the Securities Purchase Agreement, and (b) not theretofore furnished a
Conversion Notice in compliance with Section 3.2).

          (xxiv) "Registration Rights Agreement" means that certain Registration
Rights Agreement of even date herewith by and between the Company and Holder, as
the same may be amended from time to time.

          (xxv) "SEC" means the United States Securities and Exchange
Commission.

          (xxvi) "Securities Act" means the Securities Act of 1933, as amended,
and the rules and regulations of the SEC thereunder, all as in effect at the
time.

          (xxvii) "Securities Purchase Agreement" means that certain Securities
Purchase Agreement of even date herewith by and among the Company and Holder, as
the same may be amended from time to time.

          (xxviii) "Subsidiary" means any entity of which securities or other
ownership interests having ordinary voting power to elect a majority of the
board of directors or other persons performing similar functions are owned
directly or indirectly by the Company.

          (xxix) "Trading Day" means any day on which (i) purchases and sales of
securities on the principal national security exchange or quotation system on
which the Common Shares are traded are reported thereon, or, if not quoted or
listed or admitted to trading on any national securities exchange or quotation
system, as reported by Bloomberg LP or a similar generally accepted reporting
service, as the case may be, (ii) at least one bid for the trading of Common
Shares is reported and (iii) no Market Disruption Event occurs.

          All references to "cash" or "$" herein means currency of the United
States of America.

                                   ARTICLE 2
                   EXCHANGES, TRANSFER AND OPTIONAL REDEMPTION

     SECTION 2.1 Registration of Transfer of Debentures. This Debenture, when
presented for registration of transfer, shall (if so required by the Company) be
duly endorsed, or be accompanied by a written instrument of transfer in form
reasonably satisfactory to the Company duly executed, by the Holder duly
authorized in writing.

     SECTION 2.2 Loss, Theft, Destruction of Debenture. Upon receipt of evidence
satisfactory to the Company of the loss, theft, destruction or mutilation of
this Debenture and, in the case of any such loss, theft or destruction, upon
receipt of indemnity or security reasonably satisfactory to the Company, or, in
the case of any such mutilation, upon surrender and cancellation of this
Debenture, the Company shall make, issue and deliver, in lieu of such lost,
stolen, destroyed or mutilated Debenture, a new Debenture of like tenor and
unpaid Principal Amount dated as of the date hereof (which shall accrue interest

                                       4
<PAGE>

from the most recent Interest Payment Due Date on which an interest payment was
made in full). This Debenture shall be held and owned upon the express condition
that the provisions of this Section 2.2 are exclusive with respect to the
replacement of a mutilated, destroyed, lost or stolen Debenture and shall
preclude any and all other rights and remedies notwithstanding any law or
statute existing or hereafter enacted to the contrary with respect to the
replacement of negotiable instruments or other securities without the surrender
thereof.

     SECTION 2.3 Who Deemed Absolute Owner. The Company may deem the Holder in
whose name this Debenture shall be registered upon the registry books of the
Company to be, and may treat it as, the absolute owner of this Debenture
(whether or not this Debenture shall be overdue) for the purpose of receiving
payment of or on account of the Principal Amount of this Debenture, for the
conversion of this Debenture and for all other purposes, and the Company shall
not be affected by any notice to the contrary. All such payments and such
conversions shall be valid and effectual to satisfy and discharge the liability
upon this Debenture to the extent of the sum or sums so paid or the conversion
or conversions so made.

     SECTION 2.4 Repayment at Maturity. At the Maturity Date, the Company shall
repay the outstanding Principal Amount of this Debenture in whole in cash,
together with all accrued and unpaid interest thereon, in cash, to the Maturity
Date.

     SECTION 2.5 Optional Redemption. For a period of 6 months following the
Closing Date, the Company may redeem this Debenture in whole in cash for 150% of
the outstanding Principal Amount plus accrued and unpaid interest.

                                   ARTICLE 3
                             CONVERSION OF DEBENTURE

     SECTION 3.1 Conversion; Conversion Price; Valuation Event. (a) At the
option of the Holder, this Debenture may be converted, either in whole or in
part, up to the full Principal Amount hereof (in increments of $1,000 in
Principal Amount) into Common Shares (calculated as to each such conversion to
the nearest 1/100th of a share), at any time and from time to time on any
Business Day, subject to compliance with Section 3.2. The number of Common
Shares into which this Debenture may be converted is equal to the dollar amount
of the Debenture being converted multiplied by eleven, minus the product of the
Conversion Price multiplied by ten times the dollar amount of the Debenture
being converted, and the entire foregoing result shall be divided by the
Conversion Price. In addition, the Company shall pay to the Holder on the
Conversion Date, in cash, any accrued and unpaid interest on the Debenture being
converted not included at the option of the Holder in clause (i) of the
immediately preceding sentence. The "Conversion Price" shall be equal to the
lesser of (i) $0.25, or (ii) eighty percent (80%) of the average of the 5 lowest
Volume Weighted Average Prices during the twenty (20) Trading Days prior to
Holder's election to convert (a "Discount Multiplier"); provided, that in the
event the Registration Statement (as such term is defined in the "Registration
Rights Agreement") has not been declared effective by the SEC by the Deadline
or, if the Registration Statement has theretofore been declared effective but is
not thereafter effective, then the applicable Discount Multiplier shall decrease
by three percentage points (3%) for each month or partial month occurring after
the Deadline that the Registration Statement is not effective.

                                       5
<PAGE>

If the Holder elects to convert a portion of the Debenture and, on the day that
the election is made, the Volume Weighted Average Price is below $0.06, the
Company shall have the right to prepay that portion of the Debenture that Holder
elected to convert, plus any accrued and unpaid interest, at 125% of such
amount. In the event that the Company elects to prepay that portion of the
Debenture, Holder shall have the right to withdraw its Conversion Notice.

Beginning in the first full calendar month after the Registration Statement is
declared effective, Holder shall convert at least 4% of the face value of the
Debenture per calendar month into Common Shares of the Company, provided that
the Common Shares are available, registered and freely tradable. In the event
Holder breaches this provision, Holder shall not be entitled to collect interest
on the Debenture for that month. In the event Holder breaches this provision for
two consecutive months, at the option of the Company, this Agreement, the
Registration Rights Agreement, the Securities Purchase Agreement and the
associated warrants shall terminate, and the outstanding principal of this
Debenture, together with accrued but unpaid interest thereon, shall mature one
month after the end of such second consecutive month.

Commencing the date of the Deadline until the effective date of the Registration
Statement, Holder shall convert no more than 12% (such 12% maximum amount to be
cumulative from the Deadline), of the face value of the Debenture per calendar
month into Common Shares of the Company. The 12% monthly maximum amount shall
not be applicable if the Current Market Price of the Common Stock at anytime
during the applicable month is higher than the Current Market Price of the
Common Stock on the Closing Date.

          (b) Notwithstanding the provisions of Section 3.1(a), in the event the
Company's Registration Statement has not been declared effective by the Deadline
or, if the Registration Statement has theretofore been declared effective but is
not thereafter effective, the following will also apply in addition to any
damages incurred by the Holder as a result thereof:

               (i) The Holder may demand repayment of one hundred and fifty
percent (150%) of the Principal Amount of the Debenture, together with all
accrued and unpaid interest thereon, in cash, at any time prior to the Company's
Registration Statement being declared effective by the SEC or during the period
that the Company's Registration Statement is not effective, such repayment to be
made within three (3) business days of such demand. In the event that the
Debenture is so accelerated, in addition to the repayment of one hundred and
fifty percent (150%) of the Principal Amount together with accrued interest as
aforesaid, the Company shall immediately issue and pay, as the case may be, to
the Holder 50,000 Shares of Common Stock and $15,000 for each thirty (30) day
period, or portion thereof, during which the Principal Amount, including
interest thereon, remains unpaid, with the monthly payment amount to increase to
$20,000 for each thirty (30) day period, or portion thereof, after the first
ninety (90) day period;

                                       6
<PAGE>

               (ii) If the Holder does not elect to accelerate the Debenture,
the Company shall immediately issue or pay, as the case may be, to Holder 50,000
Shares of Common Stock and $15,000 for each thirty (30) day period, or portion
thereof, that the Registration Statement is not effective, with the monthly
payment amount to increase to $20,000 for each thirty (30) day period, or
portion thereof, after the first ninety (90) day period from the Deadline.

               (iii) If the SEC indicates that the Company's Registration
Statement will be declared effective upon request by the Company, and the
Company does not, within 3 business days of the SEC indication, request that the
Registration Statement become effective, the amounts set forth in subsections
(ii) and (iii) above shall double.

     SECTION 3.2 Exercise of Conversion Privilege. (a) Conversion of this
Debenture may be exercised on any Business Day by the Holder by telecopying an
executed and completed Conversion Notice to the Company. Each date on which a
Conversion Notice is telecopied to the Company in accordance with the provisions
of this Section 3.2 shall constitute a Conversion Date. The Company shall
convert this Debenture and issue the Common Stock Issued at Conversion in the
manner provided below in this Section 3.2, and all voting and other rights
associated with the beneficial ownership of the Common Stock Issued at
Conversion shall vest with the Holder, effective as of the Conversion Date at
the time specified in the Conversion Notice. The Conversion Notice also shall
state the name or names (with addresses) of the persons who are to become the
holders of the Common Stock Issued at Conversion in connection with such
conversion. As promptly as practicable after the receipt of the Conversion
Notice as aforesaid, but in any event not more than three (3) Business Days
after the Company's receipt of such Conversion Notice, the Company shall (i)
issue the Common Stock Issued at Conversion in accordance with the provisions of
this Article 3 and (ii) cause to be mailed for delivery by overnight courier, or
if a Registration Statement covering the Common Stock has been declared
effective by the SEC cause to be electronically transferred, to Holder (x) a
certificate or certificate(s) representing the number of Common Shares to which
the Holder is entitled by virtue of such conversion, (y) cash, as provided in
Section 3.3, in respect of any fraction of a Common Share deliverable upon such
conversion and (z) cash or shares of Common Stock, as applicable, representing
the amount of accrued and unpaid interest on this Debenture as of the Conversion
Date. Such conversion shall be deemed to have been effected at the time at which
the Conversion Notice indicates, and at such time the rights of the Holder of
this Debenture, as such (except if and to the extent that any Principal Amount
thereof remains unconverted), shall cease and the Person and Persons in whose
name or names the Common Stock Issued at Conversion shall be issuable shall be
deemed to have become the holder or holders of record of the Common Shares
represented thereby, and all voting and other rights associated with the
beneficial ownership of such Common Shares shall at such time vest with such
Person or Persons. The Conversion Notice shall constitute a contract between the

                                       7
<PAGE>

Holder and the Company, whereby the Holder shall be deemed to subscribe for the
number of Common Shares which it will be entitled to receive upon such
conversion and, in payment and satisfaction of such subscription (and for any
cash adjustment to which it is entitled pursuant to Section 3.4), to surrender
this Debenture and to release the Company from all liability thereon (except if
and to the extent that any Principal Amount thereof remains unconverted). No
cash payment aggregating less than $1.00 shall be required to be given unless
specifically requested by the Holder.

          If, at any time after the date of this Debenture, (i) the Company
challenges, disputes or denies the right of the Holder hereof to effect the
conversion of this Debenture into Common Shares or otherwise dishonors or
rejects any Conversion Notice delivered in accordance with this Section 3.2 or
(ii) any third party who is not and has never been an Affiliate of the Holder
commences any lawsuit or legal proceeding or otherwise asserts any claim before
any court or public or governmental authority which seeks to challenge, deny,
enjoin, limit, modify, delay or dispute the right of the Holder hereof to effect
the conversion of this Debenture into Common Shares, then the Holder shall have
the right, by written notice to the Company, to require the Company to promptly
redeem this Debenture for cash at one hundred and fifty (150%) of the Principal
Amount thereof, together with all accrued and unpaid interest thereon to the
date of redemption. Under any of the circumstances set forth above, the Company
shall be responsible for the payment of all costs and expenses of the Holder,
including reasonable legal fees and expenses, as and when incurred in defending
itself in any such action or pursuing its rights hereunder (in addition to any
other rights of the Holder).

          (a) The Holder shall be entitled to exercise its conversion privilege
notwithstanding the commencement of any case under the Bankruptcy Code. In the
event the Company is a debtor under the Bankruptcy Code, the Company hereby
waives to the fullest extent permitted any rights to relief it may have under 11
U.S.C. ss. 362 in respect of the Holder's conversion privilege. The Company
hereby waives to the fullest extent permitted any rights to relief it may have
under 11 U.S.C. ss. 362 in respect of the conversion of this Debenture. The
Company agrees, without cost or expense to the Holder, to take or consent to any
and all action necessary to effectuate relief under 11 U.S.C. ss. 362.

     SECTION 3.3 Fractional Shares. No fractional Common Shares or scrip
representing fractional Common Shares shall be delivered upon conversion of this
Debenture. Instead of any fractional Common Shares which otherwise would be
delivered upon conversion of this Debenture, the Company shall pay a cash
adjustment in respect of such fraction in an amount equal to the same fraction
multiplied by the Current Market Price on the Conversion Date. No cash payment
of less than $1.00 shall be required to be given unless specifically requested
by the Holder.

     SECTION 3.4 Adjustments. The Conversion Price and the number of shares
deliverable upon conversion of this Debenture are subject to adjustment from
time to time as follows:

          (i) Reclassification, Etc. In case the Company shall reorganize its
capital, reclassify its capital stock, consolidate or merge with or into another
Person (where the Company is not the survivor or where there is a change in or
distribution with respect to the Common Stock of the Company), sell, convey,
transfer or otherwise dispose of all or substantially all its property, assets
or business to another Person, or effectuate a transaction or series of related
transactions in which more than fifty percent (50%) of the voting power of the
Company is disposed of (each, a "Fundamental Corporate Change") and, pursuant to
the terms of such Fundamental Corporate Change, shares of common stock of the

                                       8
<PAGE>

successor or acquiring corporation, or any cash, shares of stock or other
securities or property of any nature whatsoever (including warrants or other
subscription or purchase rights) in addition to or in lieu of common stock of
the successor or acquiring corporation ("Other Property") are to be received by
or distributed to the holders of Common Stock of the Company, then the Holder of
this Debenture shall have the right thereafter, at its sole option, to (x)
require the Company to prepay this Debenture for cash at one hundred and fifty
percent (150%) of the Principal Amount thereof, together with all accrued and
unpaid interest thereon to the date of prepayment, (y) receive the number of
shares of common stock of the successor or acquiring corporation or of the
Company, if it is the surviving corporation, and Other Property as is receivable
upon or as a result of such Fundamental Corporate Change by a holder of the
number of shares of Common Stock into which the outstanding portion of this
Debenture may be converted at the Conversion Price applicable immediately prior
to such Fundamental Corporate Change or (z) require the Company, or such
successor, resulting or purchasing corporation, as the case may be, to, without
benefit of any additional consideration therefor, execute and deliver to the
Holder a debenture with substantial identical rights, privileges, powers,
restrictions and other terms as this Debenture in an amount equal to the amount
outstanding under this Debenture immediately prior to such Fundamental Corporate
Change. For purposes hereof, "common stock of the successor or acquiring
corporation" shall include stock of such corporation of any class which is not
preferred as to dividends or assets over any other class of stock of such
corporation and which is not subject to prepayment and shall also include any
evidences of indebtedness, shares of stock or other securities which are
convertible into or exchangeable for any such stock, either immediately or upon
the arrival of a specified date or the happening of a specified event and any
warrants or other rights to subscribe for or purchase any such stock. The
foregoing provisions shall similarly apply to successive Fundamental Corporate
Changes.

     SECTION 3.5 Certain Conversion Limits.

     Notwithstanding anything herein to the contrary, if and to the extent that,
on any date, the holding by the Holder of this Debenture would result in the
Holder's being deemed the beneficial owner of more than 4.99% of the then
Outstanding shares of Common Stock, then the Holder shall not have the right,
and the Company shall not have the obligation, to convert any portion of this
Debenture as shall cause such Holder to be deemed the beneficial owner of more
than 4.99% of the then Outstanding shares of Common Stock. If any court of
competent jurisdiction shall determine that the foregoing limitation is
ineffective to prevent a Holder from being deemed the beneficial owner of more
than 4.99% of the then Outstanding shares of Common Stock, then the Company
shall prepay such portion of this Debenture as shall cause such Holder not to be
deemed the beneficial owner of more than 4.99% of the then Outstanding shares of
Common Stock. Upon such determination by a court of competent jurisdiction, the
Holder shall have no interest in or rights under such portion of the Debenture.
Any and all interest paid on or prior to the date of such determination shall be
deemed interest paid on the remaining portion of this Debenture held by the
Holder. Such prepayment shall be for cash at a prepayment price of one hundred
and fifty percent (150%) of the Principal Amount thereof, together with all
accrued and unpaid interest thereon to the date of prepayment.

                                       9
<PAGE>

     SECTION 3.6 Surrender of Debenture. Upon any redemption of this Debenture
pursuant to Sections 3.2, 3.5 or 6.2, or upon maturity pursuant to Section 2.4,
the Holder shall either deliver this Debenture by hand to the Company at its
principal executive offices or surrender the same to the Company at such address
by nationally recognized overnight courier. Payment of the redemption price or
the amount due on maturity specified in Section 2.4, shall be made by the
Company to the Holder against receipt of this Debenture (as provided in this
Section 3.5) by wire transfer of immediately available funds to such account(s)
as the Holder shall specify by written notice to the Company. If payment of such
redemption price is not made in full by the redemption date, or the amount due
on maturity is not paid in full by the Maturity Date, the Holder shall again
have the right to convert this Debenture as provided in Article 3 hereof or to
declare an Event of Default.

                                   ARTICLE 4
                        STATUS; RESTRICTIONS ON TRANSFER

     SECTION 4.1 Status of Debenture. This Debenture constitutes a legal, valid
and binding obligation of the Company, enforceable in accordance with its terms
subject, as to enforceability, to general principles of equity and to principles
of bankruptcy, insolvency, reorganization and other similar laws of general
applicability relating to or affecting creditors' rights and remedies generally.

     SECTION 4.2 Restrictions on Transfer. This Debenture, and any Common Shares
deliverable upon the conversion hereof, have not been registered under the
Securities Act. The Holder by accepting this Debenture agrees that this
Debenture and the shares of Common Stock to be acquired as interest on and upon
conversion of this Debenture may not be assigned or otherwise transferred unless
and until (i) the Company has received the opinion of counsel for the Holder
that this Debenture or such shares may be sold pursuant to an exemption from
registration under the Securities Act or (ii) a registration statement relating
to this Debenture or such shares has been filed by the Company and declared
effective by the SEC.

     Each certificate for shares of Common Stock deliverable hereunder shall
bear a legend as follows unless and until such securities have been sold
pursuant to an effective registration statement under the Securities Act:

          "The securities represented by this certificate have not
          been registered under the Securities Act of 1933, as amended
          (the "Securities Act"). The securities may not be offered
          for sale, sold or otherwise transferred except (i) pursuant
          to an effective registration statement under the Securities
          Act or (ii) pursuant to an exemption from registration under
          the Securities Act in respect of which the issuer of this
          certificate has received an opinion of counsel satisfactory
          to the issuer of this certificate to such effect. Copies of
          the agreement covering both the purchase of the securities
          and restrictions on their transfer may be obtained at no
          cost by written request made by the holder of record of this
          certificate to the Secretary of the issuer of this
          certificate at the principal executive offices of the issuer
          of this certificate."

                                  10
<PAGE>

                               ARTICLE 5
                               COVENANTS

     SECTION 5.1 Conversion. The Company shall cause the transfer agent, not
later than three (3) Business Days after the Company's receipt of a Conversion
Notice, to issue and deliver to the Holder the requisite shares of Common Stock
Issued at Conversion. Such delivery shall be by electronic transfer if a
Registration Statement covering the Common Stock has been declared effective by
the SEC.

     SECTION 5.2 Notice of Default. If any one or more events occur which
constitute or which, with notice, lapse of time, or both, would constitute an
Event of Default, the Company shall forthwith give notice to the Holder,
specifying the nature and status of the Event of Default or such other event(s),
as the case may be.

     SECTION 5.3 Payment of Obligations. So long as this Debenture shall be
outstanding, the Company shall pay, extend, or discharge at or before maturity,
all its respective material obligations and liabilities, including, without
limitation, tax liabilities, except where the same may be contested in good
faith by appropriate proceedings.

     SECTION 5.4 Compliance with Laws. So long as this Debenture shall be
outstanding, the Company shall comply with all applicable laws, ordinances,
rules, regulations and requirements of governmental authorities, except for such
noncompliance which would not have a material adverse effect on the business,
properties, prospects, condition (financial or otherwise) or results of
operations of the Company and the Subsidiaries.

     SECTION 5.5 Inspection of Property, Books and Records. So long as this
Debenture shall be outstanding, the Company shall keep proper books of record
and account in which full, true and correct entries shall be made of all
material dealings and transactions in relation to its business and activities
and shall permit representatives of the Holder at the Holder's expense to visit
and inspect any of its respective properties, to examine and make abstracts from
any of its respective books and records, not reasonably deemed confidential by
the Company, and to discuss its respective affairs, finances and accounts with
its respective officers and independent public accountants, all at such
reasonable times and as often as may reasonably be desired.

     SECTION 5.6 Right of First Refusal on Other Financing. In the event that
the Company obtains any other financing (either debt, equity, or a combination
thereof) which is to close during the term of this Debenture, Holder shall be
entitled to a right of first refusal to enable it to match the terms of the

                                       11
<PAGE>

other financing. The Company shall deliver to Holder, at least ten (10) days
prior to the proposed closing date of such transaction, written notice
describing the proposed transaction, including the terms and conditions thereof,
and providing Holder an option during the ten (10) day period following delivery
of such notice to provide the financing being offered in such transaction on the
same terms as contemplated by such transaction.

                                    ARTICLE 6
                           EVENTS OF DEFAULT; REMEDIES

     SECTION 6.1 Events of Default. "Event of Default" wherever used herein
means any one of the following events:

          (i) the Company shall default in the payment of principal of or
interest on this Debenture as and when the same shall be due and payable and, in
the case of an interest payment default, such default shall continue for five
(5) Business Days after the date such interest payment was due, or the Company
shall fail to perform or observe any other covenant, agreement, term, provision,
undertaking or commitment under this Debenture, the Conversion Warrants (as
defined in the Securities Purchase Agreement), the Securities Purchase Agreement
or the Registration Rights Agreement and such default shall continue for a
period of ten (10) Business Days after the delivery to the Company of written
notice that the Company is in default hereunder or thereunder;

          (ii) any of the representations or warranties made by the Company
herein, in the Securities Purchase Agreement, the Registration Rights Agreement
or in any certificate or financial or other written statements heretofore or
hereafter furnished by or on behalf of the Company in connection with the
execution and delivery of this Debenture, the Warrants, the Securities Purchase
Agreement or the Registration Rights Agreement shall be false or misleading in a
material respect on the Closing Date;

          (iii) under the laws of any jurisdiction not otherwise covered by
clauses (iv) and (v) below, the Company or any Subsidiary (A) makes a general
assignment for the benefit of creditors, (B) institutes or has instituted
against it any proceeding seeking (x) to adjudicate it a bankrupt or insolvent,
(y) liquidation, winding-up, reorganization, arrangement, adjustment,
protection, relief or composition of it or its debts under any law relating to
bankruptcy, insolvency, reorganization or relief of debtors including any plan
of compromise or arrangement or other corporate proceeding involving or
affecting its creditors or (z) the entry of an order for relief or the
appointment of a receiver, trustee or other similar person for it or for any
substantial part of its properties and assets, and in the case of any such
official proceeding instituted against it (but not instituted by it), either the
proceeding remains undismissed or unstayed for a period of sixty (60) calendar
days, or any of the actions sought in such proceeding (including the entry of an
order for relief against it or the appointment of a receiver, trustee, custodian
or other similar official for it or for any substantial part of its properties
and assets) occurs or (D) takes any corporate action to authorize any of the
above actions;

                                       12
<PAGE>

          (iv) the entry of a decree or order by a court having jurisdiction in
the premises adjudging the Company or any Subsidiary a bankrupt or insolvent, or
approving as properly filed a petition seeking reorganization, arrangement,
adjustment or composition of or in respect of the Company under the Bankruptcy
Code or any other applicable Federal or state law, or appointing a receiver,
liquidator, assignee, trustee or sequestrator (or other similar official) of the
Company or of any substantial part of its property, or ordering the winding-up
or liquidation of its affairs, and any such decree or order continues and is
unstayed and in effect for a period of sixty (60) calendar days;

          (v) the institution by the Company or any Subsidiary of proceedings to
be adjudicated a bankrupt or insolvent, or the consent by it to the institution
of bankruptcy or insolvency proceedings against it, or the filing by it of a
petition or answer or consent seeking reorganization or relief under the
Bankruptcy Code or any other applicable federal or state law, or the consent by
it to the filing of any such petition or to the appointment of a receiver,
liquidator, assignee, trustee or sequestrator (or other similar official) of the
Company or of any substantial part of its property, or the making by it of an
assignment for the benefit of creditors, or the admission by it in writing of
its inability to pay its debts generally as and when they become due, or the
taking of corporate action by the Company in furtherance of any such action;

          (vi) a final judgment or final judgments for the payment of money
shall have been entered by any court or courts of competent jurisdiction against
the Company and remains undischarged for a period (during which execution shall
be effectively stayed) of thirty (30) days, provided that the aggregate amount
of all such judgments at any time outstanding (to the extent not paid or to be
paid, as evidenced by a written communication to that effect from the applicable
insurer, by insurance) exceeds One Hundred Thousand Dollars ($100,000);

          (vii) it becomes unlawful for the Company to perform or comply with
its obligations under this Debenture, the Conversion Warrant, the Securities
Purchase Agreement or the Registration Rights Agreement in any respect;

          (viii) the Common Shares shall be delisted from the OTCBB (the
"Trading Market" or, to the extent the Company becomes eligible to list its
Common Stock on any other national security exchange or quotation system, upon
official notice of listing on any such exchange or system, as the case may be,
it shall be the "Trading Market") or suspended from trading on the Trading
Market, and shall not be reinstated, relisted or such suspension lifted, as the
case may be, within five (5) days or;

          (ix) the Company shall default (giving effect to any applicable grace
period) in the payment of principal or interest as and when the same shall
become due and payable, under any indebtedness, individually or in the
aggregate, of more than One Hundred Thousand Dollars ($100,000);

     SECTION 6.2 Acceleration of Maturity; Rescission and Annulment. If an Event
of Default occurs and is continuing, then and in every such case the Holder may,
by a notice in writing to the Company, rescind any outstanding Conversion Notice
and declare that all amounts owing or otherwise outstanding under this Debenture
are immediately due and payable and upon any such declaration this Debenture
shall become immediately due and payable in cash at a price of one hundred and
fifty percent (150%) of the Principal Amount thereof, together with all accrued
and unpaid interest thereon to the date of payment; provided, however, in the
case of any Event of Default described in clauses (iii), (iv), (v) or (vii) of
Section 6.1, such amount automatically shall become immediately due and payable
without the necessity of any notice or declaration as aforesaid.

                                       13
<PAGE>

     SECTION 6.3 Late Payment Penalty. If any portion of the principal of or
interest on this Debenture shall not be paid within ten (10) days of when it is
due, the Discount Multiplier under this Debenture, and under all warrants
granted by the Company to the Holder, shall decrease by one percentage (1%)
point for all conversions of this Debenture and warrant exercises thereafter.

     SECTION 6.4 Maximum Interest Rate. Notwithstanding anything herein to the
contrary, if at any time the applicable interest rate as provided for herein
shall exceed the maximum lawful rate which may be contracted for, charged, taken
or received by the Holder in accordance with any applicable law (the "Maximum
Rate"), the rate of interest applicable to this Debenture shall be limited to
the Maximum Rate. To the greatest extent permitted under applicable law, the
Company hereby waives and agrees not to allege or claim that any provisions of
this Note could give rise to or result in any actual or potential violation of
any applicable usury laws.

     SECTION 6.5 Remedies Not Waived. No course of dealing between the Company
and the Holder or any delay in exercising any rights hereunder shall operate as
a waiver by the Holder.

     SECTION 6.6 Remedies. The Company acknowledges that a breach by it of its
obligations hereunder will cause irreparable harm to the Holder, by vitiating
the intent and purpose of the transaction contemplated hereby. Accordingly, the
Company acknowledges that the remedy at law for a breach of its obligations
under this Debenture will be inadequate and agrees, in the event of a breach or
threatened breach by the Company of the provisions of this Debenture, that the
Holder shall be entitled to all other available remedies at law or in equity,
and in addition to the penalties assessable herein, to an injunction or
injunctions restraining, preventing or curing any breach of this Debenture and
to enforce specifically the terms and provisions thereof, without the necessity
of showing economic loss and without any bond or other security being required.

     SECTION 6.7 Payment of Certain Amounts. Whenever pursuant to this Debenture
the Company is required to pay an amount in excess of the Principal Amount plus
accrued and unpaid interest, the Company and the Holder agree that the actual
damages to the Holder from the receipt of cash payment on this Debenture may be
difficult to determine and the amount to be so paid by the Company represents
stipulated damages and not a penalty and is intended to compensate the Holder in
part for loss of the opportunity to convert this Debenture and to earn a return
from the sale of shares of Common Stock acquired upon conversion of this
Debenture at a price in excess of that price paid for such shares pursuant to
this Debenture. The Company and the Holder hereby agree that such amount of
stipulated damages is not disproportionate to the possible loss to the Holder
from the receipt of a cash payment without the opportunity to convert this
Debenture into shares of Common Stock.

                                       14
<PAGE>

                                    ARTICLE 7
                                  MISCELLANEOUS

     SECTION 7.1 Notice of Certain Events. In the case of the occurrence of any
event described in Section 3.4 of this Debenture, the Company shall cause to be
mailed to the Holder of this Debenture at its last address as it appears in the
Company's security registry, at least twenty (20) days prior to the applicable
record, effective or expiration date hereinafter specified (or, if such twenty
(20) days' notice is not possible, at the earliest possible date prior to any
such record, effective or expiration date), a notice thereof, including, if
applicable, a statement of (y) the date on which a record is to be taken for the
purpose of such dividend, distribution, issuance or granting of rights, options
or warrants, or if a record is not to be taken, the date as of which the holders
of record of Common Stock to be entitled to such dividend, distribution,
issuance or granting of rights, options or warrants are to be determined or (z)
the date on which such reclassification, consolidation, merger, sale, transfer,
dissolution, liquidation or winding-up is expected to become effective, and the
date as of which it is expected that holders of record of Common Stock will be
entitled to exchange their shares for securities, cash or other property
deliverable upon such reclassification, consolidation, merger, sale transfer,
dissolution, liquidation or winding-up.

     SECTION 7.2 Register. The Company shall keep at its principal office a
register in which the Company shall provide for the registration of this
Debenture. Upon any transfer of this Debenture in accordance with Articles 2 and
4 hereof, the Company shall register such transfer on the Debenture register.

     SECTION 7.3 Withholding. To the extent required by applicable law, the
Company may withhold amounts for or on account of any taxes imposed or levied by
or on behalf of any taxing authority in the United States having jurisdiction
over the Company from any payments made pursuant to this Debenture.

     SECTION 7.4 Transmittal of Notices. Except as may be otherwise provided
herein, any notice or other communication or delivery required or permitted
hereunder shall be in writing and shall be delivered personally, or sent by
telecopier machine or by a nationally recognized overnight courier service, and
shall be deemed given when so delivered personally, or by telecopier machine or
overnight courier service as follows:

                  (1) if to the Company, to:

                      Integrated Surgical Systems, Inc.
                      1850 Research Park Drive
                      Davis, CA 95616
                      Telephone:       530-792-2600
                      Facsimile:       530-792-2690


                                       15
<PAGE>

                      With a copy to:

                      Snow Becker Krauss P.C.
                      605 3rd Avenue
                      New York, NY 10158
                      Telephone:       212-687-3860
                      Facsimile:       212-949-7052
                      Attn:    Jack Becker, Esq.


                  (2) if to the Holder, to:

                      Golden Gate Investors, Inc.
                      7817 Herschel Avenue, Suite 200
                      La Jolla, California 92037
                      Telephone:       858-551-8789
                      Facsimile:       858-551-8779

Each of the Holder or the Company may change the foregoing address by notice
given pursuant to this Section 7.4.

     SECTION 7.5 Attorneys' Fees. Should any party hereto employ an attorney for
the purpose of enforcing or construing this Debenture, or any judgment based on
this Debenture, in any legal proceeding whatsoever, including insolvency,
bankruptcy, arbitration, declaratory relief or other litigation, the prevailing
party shall be entitled to receive from the other party or parties thereto
reimbursement for all reasonable attorneys' fees and all reasonable costs,
including but not limited to service of process, filing fees, court and court
reporter costs, investigative costs, expert witness fees, and the cost of any
bonds, whether taxable or not, and that such reimbursement shall be included in
any judgment or final order issued in that proceeding. The "prevailing party"
means the party determined by the court to most nearly prevail and not
necessarily the one in whose favor a judgment is rendered.

     SECTION 7.6 Governing Law. This Debenture shall be governed by, and
construed in accordance with, the laws of the State of California (without
giving effect to conflicts of laws principles). With respect to any suit, action
or proceedings relating to this Debenture, the Company irrevocably submits to
the exclusive jurisdiction of the courts of the State of California sitting in
San Diego and the United States District Court located in the City of San Diego
and hereby waives, to the fullest extent permitted by applicable law, any claim
that any such suit, action or proceeding has been brought in an inconvenient
forum. Subject to applicable law, the Company agrees that final judgment against
it in any legal action or proceeding arising out of or relating to this
Debenture shall be conclusive and may be enforced in any other jurisdiction
within or outside the United States by suit on the judgment, a certified copy of
which judgment shall be conclusive evidence thereof and the amount of its
indebtedness, or by such other means provided by law.

                                       16
<PAGE>

     SECTION 7.7 Waiver of Jury Trial. To the fullest extent permitted by law,
each of the parties hereto hereby knowingly, voluntarily and intentionally
waives its respective rights to a jury trial of any claim or cause of action
based upon or arising out of this Debenture or any other document or any
dealings between them relating to the subject matter of this Debenture and other
documents. Each party hereto (i) certifies that neither of their respective
representatives, agents or attorneys has represented, expressly or otherwise,
that such party would not, in the event of litigation, seek to enforce the
foregoing waivers and (ii) acknowledges that it has been induced to enter into
this Debenture by, among other things, the mutual waivers and certifications
herein.

     SECTION 7.8 Headings. The headings of the Articles and Sections of this
Debenture are inserted for convenience only and do not constitute a part of this
Debenture.

     SECTION 7.9 Payment Dates. Whenever any payment hereunder shall be due on a
day other than a Business Day, such payment shall be made on the next succeeding
Business Day.

     SECTION 7.10 Binding Effect. Each Holder by accepting this Debenture agrees
to be bound by and comply with the terms and provisions of this Debenture.

     SECTION 7.11 No Stockholder Rights. Except as otherwise provided herein,
this Debenture shall not entitle the Holder to any of the rights of a
stockholder of the Company, including, without limitation, the right to vote, to
receive dividends and other distributions, or to receive any notice of, or to
attend, meetings of stockholders or any other proceedings of the Company, unless
and to the extent converted into shares of Common Stock in accordance with the
terms hereof.

     SECTION 7.12 Facsimile Execution. Facsimile execution shall be deemed
originals.

     IN WITNESS WHEREOF, the Company has caused this Debenture to be signed by
its duly authorized officer on the date of this Debenture.





Integrated Surgical Systems, Inc.


By: /s/ RAMESH C. TRIVEDI
- -------------------------
Ramesh C. Trivedi
President and CEO








                                       17
- -------------------------                            ---------------------------
Initials                                                                Initials

<PAGE>

                                    EXHIBIT A
                           DEBENTURE CONVERSION NOTICE


TO: Integrated Surgical Systems, Inc.



     The undersigned owner of this Convertible Debenture due June ___, 2006 (the
"Debenture") issued by Integrated Surgical Systems, Inc. (the "Company") hereby
irrevocably exercises its option to convert $__________ Principal Amount of the
Debenture into shares of Common Stock in accordance with the terms of the
Debenture. The undersigned hereby instructs the Company to convert the portion
of the Debenture specified above into shares of Common Stock Issued at
Conversion in accordance with the provisions of Article 3 of the Debenture. The
undersigned directs that the Common Stock and certificates therefor deliverable
upon conversion, the Debenture reissued in the Principal Amount not being
surrendered for conversion hereby, [the check or shares of Common Stock in
payment of the accrued and unpaid interest thereon to the date of this Notice,]
together with any check in payment for fractional Common Stock, be registered in
the name of and/or delivered to the undersigned unless a different name has been
indicated below. All capitalized terms used and not defined herein have the
respective meanings assigned to them in the Debenture. The conversion pursuant
hereto shall be deemed to have been effected at the date and time specified
below, and at such time the rights of the undersigned as a Holder of the
Principal Amount of the Debenture set forth above shall cease and the Person or
Persons in whose name or names the Common Stock Issued at Conversion shall be
registered shall be deemed to have become the holder or holders of record of the
Common Shares represented thereby and all voting and other rights associated
with the beneficial ownership of such Common Shares shall at such time vest with
such Person or Persons.

Date and time:  __________________



__________________________________

By: ______________________________

Title: ___________________________

Fill in for registration of Debenture:
Please print name and address
(including ZIP code number):


__________________________________

__________________________________



</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.2
<SEQUENCE>3
<FILENAME>iss10-2.txt
<DESCRIPTION>WARRANT
<TEXT>
                                  EXHIBIT 10.2


                        WARRANT TO PURCHASE COMMON STOCK

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE BEEN ACQUIRED FOR INVESTMENT
AND NOT FOR DISTRIBUTION, AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT
OF 1933, AS AMENDED NEITHER THE WARRANT NOR THE SHARES MAY BE SOLD, PLEDGED, OR
OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT
OR PURSUANT TO RULE 144 OR AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE
COMPANY AND ITS COUNSEL THAT SUCH REGISTRATION IS NOT REQUIRED. THIS WARRANT
MUST BE SURRENDERED TO THE COMPANY OR ITS TRANSFER AGENT AS A CONDITION
PRECEDENT TO THE SALE, PLEDGE OR OTHER TRANSFER OF ANY INTEREST IN THIS WARRANT
OR THE SHARES ISSUABLE HEREUNDER.

Issuer:  Integrated Surgical Systems, Inc.
Class of Stock: Common Stock
Issue Date: June 9, 2004
Expiration Date: June 9, 2006

     THIS WARRANT CERTIFICATE is being issued pursuant to that certain
Securities Purchase Agreement dated as of the date hereof (the "Securities
Purchase Agreement") between Integrated Surgical Systems, Inc., a Delaware
corporation (the "Company") and Golden Gate Investors, Inc., a California
corporation ("Holder"). Terms not defined herein shall have the meanings
ascribed to them in the Securities Purchase Agreement or the 6 3/4 % Convertible
Debenture ("Debenture").

          1.1 Warrants. The Company hereby grants to Holder the right to
purchase 1,500,000 shares of the Company's Common Stock (the "Shares" or
"Warrant Shares"). For avoidance of doubt, this Warrant may be exercised
concurrently with or subsequent to the issuance of a Conversion Notice under the
Debenture in accordance with the Securities Purchase Agreement. The date that
the Holder issues a Conversion Notice under the Debenture is hereafter referred
to as the "Conversion Date." Holder agrees that, beginning in the first full
calendar month after the Registration Statement is declared effective with the
SEC,

Beginning in the first full calendar month after the Registration Statement is
declared effective, Holder will exercise at least 4% of the Warrants per
calendar month, in conjunction with the issuance of Conversion Notices under the
Debenture, provided that the Common Shares are available, registered and freely
tradable. In the event Holder breaches this provision, Holder shall not be
entitled to collect interest on the Debenture for that month. In the event
Holder breaches this provision for two consecutive months, at the option of the
Company, this Agreement, the Registration Rights Agreement, the Securities
Purchase Agreement and the associated Debenture shall terminate, and the
outstanding principal of the Debenture, together with accrued but unpaid
interest thereon, shall mature one month after the end of such second
consecutive month.

Holder will exercise no more than 12% (such 12% maximum amount to be cumulative
from the Deadline), of the Warrants per calendar month. The 12% monthly maximum
amount shall not be applicable if the Current Market Price of the Common Stock
at anytime during the applicable month is higher than the Current Market Price
of the Common Stock on the Closing Date.

                                       1
- -------------------------                            ---------------------------
Initials                                                                Initials

<PAGE>

This Warrant shall expire and Holder shall no longer be able to purchase the
Warrant Shares on June 9, 2006.

                                    ARTICLE 2
                                    EXERCISE

          2.1 Method of Exercise. Holder may exercise this Warrant Certificate
by delivering a duly executed warrant notice of exercise in substantially the
form attached hereto as Appendix A ("Warrant Notice of Exercise") to the
principal office of the Company.

          2.2 Delivery of Certificate and New Warrant. As promptly as
practicable after the receipt of the Warrant Notice of Exercise, but in any
event not more than three (3) Business Days after the Company's receipt of the
Warrant Notice of Exercise, the Company shall issue the Warrant Shares and cause
to be mailed for delivery by overnight courier, or if a Registration Statement
covering the Warrant Shares has been declared effective by the SEC cause to be
electronically transferred, to Holder a certificate representing the Warrant
Shares acquired and, if this Warrant has not been fully exercised and has not
expired, a new Warrant Certificate substantially in the form of this Warrant
representing the right to acquire the portion of the Warrant Shares not so
exercised shall be delivered to Holder.

          2.3 Replacement of Warrants. On receipt of evidence reasonably
satisfactory to the Company of the loss, theft, destruction or mutilation of
this Warrant Certificate and, in the case of loss, theft or destruction, on
delivery of an indemnity agreement reasonably satisfactory in form and amount to
the Company or, in the case of mutilation, or surrender and cancellation of this
Warrant Certificate, the Company at its expense shall execute and deliver, in
lieu of this Warrant Certificate, a new warrant certificate of like tenor.

          2.4 Exercise Price. The Exercise Price of this Warrant shall be $1.00
per Share.

          2.5 Cashless Exercise. Notwithstanding anything to the contrary
contained in this Warrant Certificate, if the resale of the Warrant Shares by
the Holder is not then registered pursuant to an effective Registration
Statement, upon the expiration of one year from April 2, 2004 (the "Issue
Date"), this Warrant may be exercised by presentation and surrender of this
Warrant to the Company at its principal executive offices with a written notice
of Holder's intention to effect a cashless exercise, including a calculation of
the number of shares of Common Stock to be issued upon such exercise in
accordance with the terms hereof ( a "Cashless Exercise"). In the event of a
Cashless Exercise, in lieu of paying the Exercise Price in cash, Holder shall
surrender this Warrant for that number of Warrant Shares determined by
multiplying the number of Warrant Shares to which it otherwise would be entitled
by a fraction, the numerator of which shall be the difference between the then
current Market Price per share of the Common Stock and the Exercise Price, and
the denominator or which shall be the then Current Market Price per share of
Common Stock.

                                       2
<PAGE>

          2.6 Mandatory Exercise. In accordance with the Securities Purchase
Agreement, at anytime Holder shall convert all or any part of the Debenture,
Holder shall simultaneously therewith exercise Warrants in a dollar amount equal
to ten times the dollar amount of the Debenture conversion.

                                    ARTICLE 3
                        ADJUSTMENT TO THE WARRANT SHARES

     The number of Warrant Shares purchasable upon the exercise of this Warrant
and the Exercise Price shall be subject to adjustment from time to time upon the
occurrence of certain events, as follows:

          3.1 Reclassification. In case of any reclassification or change of
outstanding securities of the class issuable upon exercise of this Warrant then,
and in any such case, the Holder, upon the exercise hereof at any time after the
consummation of such reclassification or change, shall be entitled to receive in
lieu of each Warrant Share theretofore issuable upon exercise of this Warrant,
the kind and amount of shares of stock, other securities, money and/or property
received upon such reclassification or change by a holder of one Warrant Share.
The provisions of this Section 2.1 shall similarly apply to successive
reclassifications or changes.

          3.2 Subdivision or Combination of Common Stock. If the Company at any
time while this Warrant remains outstanding and unexpired shall subdivide or
combine its Common Stock, the Exercise Price shall be proportionately decreased
in the case of a subdivision or increased in the case of a combination.

          3.3 Stock Dividends. If the Company, at any time while this Warrant is
outstanding shall pay a dividend payable in shares of Common Stock, or make any
other distribution of shares of Common Stock (except any distribution
specifically provided for in Section 2.1 and Section 2.2 above), then the
Exercise Price shall be adjusted, effective from and after the date of
determination of shareholders entitled to receive such dividend or distribution,
to that price determined by multiplying the Exercise Price in effect immediately
prior to such date of determination by a fraction, (a) the numerator of which
shall be the total number of shares of Common Stock outstanding immediately
prior to such dividend or distribution, and (b) the denominator of which shall
be the total number of shares of Common Stock outstanding immediately after such
dividend or distribution.

          3.4 Non-Cash Dividends. If the Company at any time while this Warrant
is outstanding shall pay a dividend payable in securities other than Common
Stock or other non-cash property, or make any other distribution of such
securities or property (except any distribution specifically provided for in
Section 2.1 and Section 2.2 above), then this Warrant shall represent the right
to acquire upon exercise of this Warrant such securities or property which the
Holder would have been entitled to receive upon such dividend or distribution
had such Warrant been exercised in full immediately prior thereto, without the
payment by the Holder of any additional consideration for such securities or
property.

          3.5 Effect of Reorganization and Asset Sales. If any (i)
reorganization or reclassification of the Common Stock (ii) consolidation or
merger of the Company with or into another corporation, or (iii) sale or all or
substantially all of the Company's operating assets to another corporation
followed by a liquidation of the Company (any such transaction shall be referred
to herein as an "Event"), is effected in such a way that holders of Common Stock
are entitled to receive securities and/or assets as a result of their Common
Stock ownership, the Holder, upon exercise of this Warrant, shall be entitled to
receive such shares of stock securities or assets which the Holder would have
received had it fully exercised this Warrant on or prior the record date for

                                       3
<PAGE>

such Event. The Company shall not merge into or consolidate with another
corporation or sell all of its assets to another corporation for a consideration
consisting primarily of securities of such corporation, unless the successor or
acquiring corporation, as the case may be, shall expressly assume the due and
punctual observance and performance of each and every covenant and condition of
this Warrant Certificate to be performed or observed by the Company and all of
the obligations and liabilities hereunder, subject to such modification as shall
be necessary to provide for adjustments which shall be as nearly equivalent as
practicable to the adjustments provided for in this Section 2. The foregoing
provisions shall similarly apply to successive mergers, consolidations or sales
of assets.

          3.6 Adjustment of Number of Warrant Shares. Upon each adjustment in
the Exercise Price, the number of Warrant Shares shall be adjusted, to the
nearest whole share, to the product obtained by multiplying the number of
Warrant Shares, purchasable immediately prior to such adjustment by a fraction,
the numerator of which shall be the Exercise Price immediately prior to such
adjustment and the denominator of which shall be the Exercise Price immediately
thereafter.

          3.7 No Impairment. The Company shall not, by amendment of its articles
of incorporation or through a reorganization, transfer of assets, consolidation,
merger, dissolution, issue, or sale of securities or any other voluntary action,
avoid or seek to avoid the observance or performance of any of the terms to be
observed or performed under this Warrant Certificate by the Company, but shall
at all times in good faith assist in carrying out all of the provisions of this
Warrant Certificate and in taking all such action as may be reasonably necessary
or appropriate to protect Holder's rights hereunder against impairment. If the
Company takes any action affecting its Common Stock other than as described
above that adversely affects Holder's rights under this Warrant Certificate, the
Exercise Price shall be adjusted downward and the number of Warrant Shares
issuable upon exercise of this Warrant shall be adjusted upward in such a manner
that the aggregate Exercise Price of this Warrant is unchanged.

          3.8 Fractional Warrant Shares. No fractional Warrant Shares shall be
issuable upon the exercise of this Warrant, and the number of Warrant Shares to
be issued shall be rounded down to the nearest whole Share.

          3.9 Certificate as to Adjustments. Upon any adjustment of the Exercise
Price, the Company, at its expense, shall compute such adjustment and furnish
Holder with a certificate of its Chief Financial Officer setting forth such
adjustment and the facts upon which such adjustment is based. The Company shall,
upon written request, furnish Holder a certificate setting forth the Exercise
Price in effect upon the date thereof and the series of adjustments leading to
such Exercise Price.

          3.10 No Rights of Shareholders. This Warrant does not entitle Holder
to any voting rights or any other rights as a shareholder of the Company prior
to the exercise of Holder's right to purchase Warrant Shares as provided herein.

                                       4
<PAGE>

                                    ARTICLE 4
                  REPRESENTATIONS AND COVENANTS OF THE COMPANY

          4.1 Representations and Warranties. The Company hereby represents and
warrants to Holder that all Warrant Shares which may be issued upon the exercise
of the purchase right represented by this Warrant Certificate, shall, upon
issuance, be duly authorized, validly issued, fully paid and nonasessable, and
free of any liens and encumbrances.

          4.2 Notice of Certain Events. If the Company proposes at any time (a)
to declare any dividend or distribution upon its Common Stock, whether in cash,
property, stock, or other securities and whether or not a regular cash dividend;
(b) to offer for subscription pro rata to the holders of any class or series of
its stock any additional shares of stock of any class or series or other rights;
(c) to effect any reclassification or recapitalization of Common Stock; (d) to
merge or consolidate with or into any other corporation, or sell, lease,
license, or convey all or substantially all of its assets, or to liquidate,
dissolve or wind up; or (e) offer holders of registration rights the opportunity
to participate in an underwritten public offering of the Company's securities
for cash, then, in connection with each such event, the Company shall give
Holder (1) at least 20 days prior written notice of the date on which a record
will be taken for such dividend, distribution, or subscription rights (and
specifying the date on which the holders of Common Stock will be entitled
thereto) or for determining rights to vote, if any, in respect of the matters
referred to in (c) and (d) above; (2) in the case of the matters referred to in
(c) and (d) above at least 20 days prior written notice of the date when the
same will take place (and specifying the date on which the holders of Common
Stock will be entitled to exchange their Common Stock for securities or other
property deliverable upon the occurrence of such event); and (3) in the case of
the matter referred to in (e) above, the same notice as is given to the holders
of such registration rights.

          4.3 Information Rights. So long as Holder holds this Warrant and/or
any of the Warrant Shares, the Company shall deliver to Holder (a) promptly
after mailing, copies of all notices or other written communications to the
shareholders of the Company, (b) within ninety (90) days of their availability,
the annual audited financial statements of the Company certified by independent
public accountants of recognized standing, and (c) within forty-five (45) days
after the end of each fiscal quarter or each fiscal year, the Company's
quarterly, unaudited financial statements.

          4.4 Reservation of Warrant Shares. The Company has reserved and will
keep available, out of the authorized and unissued Warrant Shares of Common
Stock, the full number of shares of Common Stock sufficient to provide for the
exercise of the rights of purchase represented by this Warrant.

          4.5 Registration Rights. If Holder exercises this Warrant and
purchases some or all of the Warrant Shares, Holder shall have the Registration
Rights set forth in that certain Registration Rights Agreement executed
concurrently therewith.

                                   ARTICLE 5
                   REPRESENTATIONS AND COVENANTS OF THE HOLDER

          5.1 Private Issue. Holder understands (i) that the Warrant Shares
issuable upon exercise of Holder's rights contained in this Warrant Certificate
are not registered under the Securities Act of 1933, as amended (the "Securities
Act") or qualified under applicable state securities laws on the ground that the
issuance contemplated by this Warrant Certificate will be exempt from the
registration and qualifications requirements thereof, and (ii) that the
Company's reliance on such exemption is predicated on Holder's representations
set forth in this Article 5.

                                       5
<PAGE>

          5.2 Financial Risk. Holder has such knowledge and experience in
financial and business matters as to be capable of evaluating the merits and
risks of its investment and has the ability to bear the economic risks of its
investment.

          5.3 Risk of No Registration. Holder understands that if the Company
does not register with the Securities and Exchange Commission pursuant to
Section 12 of the Securities Act, or file reports pursuant to Section 15(d), of
the Securities Exchange Act of 1934 , or if a registration statement covering
the securities under the Securities Act is not in effect when it desires to sell
(i) the right to purchase the Warrant Shares pursuant to the Warrant, or (ii)
the Warrant Shares issuable upon exercise of the right to purchase, it may be
required to hold such securities for an indefinite period.

          5.4 Accredited Investor. Holder is an "accredited investor," as such
term is defined in Rule 501(a) of Regulation D promulgated under the Securities
Act.

          5.5 Investment. Holder is purchasing the Warrant and the Warrant
Shares for its own account, for investment purposes only and not with a view
toward or in connection with the public sale or distribution thereof in
violation of the Securities Act.

                                    ARTICLE 6
                                  MISCELLANEOUS

          6.1 Term. This Warrant is exercisable, in whole or in part, at any
time and from time to time on or after the Conversion Date and on or before June
9, 2006.

          6.2 Compliance with Securities Laws on Transfer. This Warrant may not
be transferred or assigned in whole or in part without compliance with
applicable federal and state securities laws by the transferor and the
transferee (including, without limitation, the delivery of investment
representation letters and legal opinions reasonably satisfactory to the
Company, as reasonably requested by the Company). The Company shall not require
Holder to provide an opinion of counsel if the transfer is to an affiliate of
Holder.

          6.3 Transfer Procedure. Holder shall have the right without the
consent of the Company to transfer or assign in whole or in part this Warrant
and the Warrant Shares issuable upon exercise of this Warrant, provided such
transfer is in compliance with Federal and state securities laws. Holder agrees
that unless there is in effect a registration statement under the Securities Act
covering the proposed transfer of all or part of this Warrant, prior to any such
proposed transfer the Holder shall give written notice thereof to the Company (a
"Transfer Notice"). Each Transfer Notice shall describe the manner and
circumstances of the proposed transfer in reasonable detail and, if the Company
so requests, shall be accompanied by an opinion of legal counsel, in a form
reasonably satisfactory to the Company, to the effect that the proposed transfer
may be effected without registration under the Securities Act; provided that the
Company will not require opinions of counsel for transactions involving
transfers to affiliates or pursuant to Rule 144 promulgated by the Securities
and Exchange Commission under the Securities Act, except in unusual
circumstances.

                                       6
<PAGE>

          6.4 Notices, etc. All notices and other communications required or
permitted hereunder shall be in writing and shall be delivered personally, or
sent by telecopier machine or by a nationally recognized overnight courier
service, and shall be deemed given when so delivered personally, or by
telecopier machine or overnight courier service as follows:

         if  to the Company, to:

         Integrated Surgical Systems, Inc.
         1850 Research Park Drive
         Davis, CA 95616
         Telephone:        530-792-2600
         Facsimile:        530-792-2690

         With a copy to:

         Snow Becker Krauss P.C.
         605 3rd Avenue
         New York, NY 10158
         Telephone:        212-687-3860
         Facsimile:        212-949-7052
         Attn:     Jack Becker, Esq.


         if to the Holder, to:

         Golden Gate Investors, Inc.
         7817 Herschel Avenue, Suite 200
         La Jolla, CA 92037
         Telephone:        858-551-8789
         Facsimile:        858-551-8779

or at such other address as the Company shall have furnished to the Holder. Each
such notice or other communication shall for all purposes of this agreement be
treated as effective or having been given when delivered if delivered
personally, or, if sent by mail, at the earlier of its receipt or five days
after the same has been deposited in a regularly maintained receptacle for the
deposit of the United States mail, addressed and mailed as aforesaid.

          6.5 Counterparts. This Warrant Certificate may be executed in any
number of counterparts, each of which shall be enforceable against the parties
actually executing such counterparts, and all of which together shall constitute
one instrument. Facsimile execution shall be deemed originals.

          6.6 Waiver. This Warrant Certificate and any term hereof may be
changed, waived, discharged or terminated only by an instrument in writing
signed by the party against which enforcement of such change, waiver, discharge
or termination is sought.

                                       7
<PAGE>

          6.7 Attorneys Fees. In the event of any dispute between the parties
concerning the terms and provisions of this Warrant Certificate, the party
prevailing in such dispute shall be entitled to collect from the other party all
costs incurred in such dispute, including reasonable attorneys fees.

          6.8 Governing Law; Jurisdiction. This Warrant Certificate shall be
governed by and construed in accordance with the laws of the State of
California, without giving effect to its principles regarding conflicts of law.
Each of the parties hereto consents to the jurisdiction of the federal courts
whose districts encompass any part of the City of San Diego or the state courts
of the State of California sitting in the City of San Diego in connection with
any dispute arising under this Warrant Certificate and hereby waives, to the
maximum extent permitted by law, any objection including any objection based on
forum non conveniens, to the bringing of any such proceeding in such
jurisdictions.

          6.9 Remedies. The Company acknowledges that a breach by it of its
obligations hereunder will cause irreparable harm to the Holder, by vitiating
the intent and purpose of the transactions hereby. Accordingly, the Company
acknowledges that the remedy at law for a breach of its obligations under this
Warrant Certificate will be inadequate and agrees, in the event of a breach or
threatened breach by the Company of the provisions of this Warrant Certificate,
that the Holder shall be entitled, in addition to all other available remedies
at law or in equity, and in addition to the penalties assessable herein, to an
injunction or injunctions restraining, preventing or curing any breach of this
Warrant Certificate and to enforce specifically the terms and provisions hereof,
without the necessity of showing economic loss and without any bond or other
security being required.

     IN WITNESS WHEREOF, the parties hereto have duly caused this Warrant
Certificate to be executed and delivered on the first date set forth above.



Integrated Surgical Systems, Inc.             Golden Gate Investors, Inc.

By: /s/ RAMESH C. TRIVEDI                     By: /s/ TRAVIS W. HUFF
    -------------------------                     -------------------------
    Ramesh C. Trivedi,                            Travis W. Huff,
    President and CEO                             Portfolio Manager








                                        8
- -------------------------                            ---------------------------
Initials                                                                Initials

<PAGE>

                                   APPENDIX 1

                           WARRANT NOTICE OF EXERCISE

     1. The undersigned hereby elects to purchase _____ shares of the Common
Stock of Integrated Surgical Systems, Inc. pursuant to the terms of the Warrant
Certificate dated June ___, 2004.

     2. Please issue a certificate or certificates representing said shares in
the name of the undersigned or in such other name as is specified below:

                              ---------------------
                              ---------------------
                              ---------------------
                               (Name and Address)

     3. The undersigned makes the representations and covenants set forth in
Article 5 of the Warrant Certificate.



- --------------------------------
(Signature)

- --------------------------------
(Date)


















<PAGE>

                      ADDENDUM TO CONVERTIBLE DEBENTURE AND
                        WARRANT TO PURCHASE COMMON STOCK


This Addendum to Convertible Debenture and Warrant tp Purchase Stock
("Addendum") is entered into on the 9th day of June 2004 by and between
Integrated Surgical Systems, Inc., a Delaware corporation ("Integratede"), and
Golden Gate Investors, Inc., a California Corporation ("GGI").

WHEREAS, GGI and Integrated are parties to that certain 6 3/4 % Convertible
Debenture dated as of June 9, 2004 ("Debenture"); and

WHEREAS, GGI and Integrated are parties to that certain Warrant to Purchase
Common Stock dated as of June9, 2004 ("Warrant"); and

WHEREAS, the parties desire to amend the Debenture and Warrants in certain
respects.

NOW, THEREFORE, in consideration of mutual promises and convenants contained
herein, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, Integrated and GGI, agree as
follows:

1.   All terms used herein and not otherwise defined herein shall have the
     definitions se forth in the debenture

2.   When the Debenture Principle Amount declines below $50,000, LJCI shall be
     permitted, for a period of 90 days, to add up to $100,000 of additional
     pricipal to the Debenture, on the same terms and conditions as the
     Debenture.

3.   Except as specifically amended herein, all other terms and conditions of
     the Debenture and Warrant shall remain in full force and effect.

IN WITNESS WHEREOF, Integrated and GGI have caused this Addendum to be signed by
its duly authorized officers on the date first set forth above.

Integrated Surgical Systems, Inc.             Golden Gate Investors, Inc.

By: /s/ RAMESH C. TRIVEDI                     By: /s/ TRAVIS W. HUFF
    -------------------------------               ------------------------------
    Ramesh C. Trivedi                             Travis W. Huff,
    President and CEO                             Portfolio Manager






</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.3
<SEQUENCE>4
<FILENAME>iss10-3.txt
<DESCRIPTION>AGREEMENT
<TEXT>

                                   EHIBIT 10.3



                          SECURITIES PURCHASE AGREEMENT

     Securities Purchase Agreement dated as of June 9, 2004 (this "Agreement")
by and between Integrated Surgical Systems, Inc., a Delaware corporation, with
principal executive offices located at 1850 Research Park Drive, Davis, CA 95616
(the "Company"), and Golden Gate Investors, Inc., a California corporation, with
principal executive offices at 7817 Herschel Avenue, Suite 200, La Jolla, CA
92037 ("Buyer").

     WHEREAS, Buyer desires to purchase from the Company, and the Company
desires to issue and sell to Buyer, upon the terms and subject to the conditions
of this Agreement, the Convertible Debenture of the Company in the aggregate
principal amount of $150,000 (the "Debenture"); and

     WHEREAS, in conjunction with the Debenture, the Company has issued a
Warrant to Purchase Common Stock to the Buyer (the "Warrant or Conversion
Warrant"); and

     WHEREAS, upon the terms and subject to the conditions set forth in the
Debenture and the Warrant, the Debenture and Warrant are convertible and
exercisable, respectively, into shares of the Company's common stock, $0.01 par
value per share (the "Common Stock");

     NOW, THEREFORE, in consideration of the premises and the mutual covenants
contained herein, the parties hereto, intending to be legally bound, hereby
agree as follows:

     I.   PURCHASE AND SALE OF DEBENTURE AND WARRANT

     A. Transaction. Buyer hereby agrees to purchase from the Company, and the
Company has offered and hereby agrees to issue and sell to Buyer in a
transaction exempt from the registration and prospectus delivery requirements of
the Securities Act of 1933, as amended (the "Securities Act"), the Debenture and
Warrant.

Purchase Price; Form of Payment. The purchase price for the Debenture to be
purchased by Buyer hereunder shall be $150,000 for the Debenture and $250 for
the Warrant (the "Purchase Price"). Simultaneously with the execution of this
Agreement, Buyer shall pay $100,000 of the Purchase Price (the "Initial Purchase
Price") by wire transfer of immediately available funds to the Company.
Simultaneously with the execution of this Agreement, the Company shall deliver
the Convertible Debenture and the Conversion Warrants (which shall have been
duly authorized, issued and executed I/N/O Buyer or, if the Company otherwise
has been notified, I/N/O Buyer's nominee).

     II.  BUYER'S REPRESENTATIONS AND WARRANTIES

     Buyer represents and warrants to and covenants and agrees with the Company
as follows:

     B. Buyer is purchasing the Debenture and the Common Stock issuable upon
conversion or redemption of the Debenture (the "Conversion Shares") and the
Warrant and the shares issuable upon exercise of the Warrant (the "Warrant
Shares") for its own account, for investment purposes only and not with a view
towards or in connection with the public sale or distribution thereof in
violation of the Securities Act. The Debenture, Conversion Shares, Warrant and
Warrant Shares are collectively referred to as the "Securities".

                                       1
- -------------------------                           ----------------------------
Initials                                                                Initials
<PAGE>

     C. Buyer is (i) an "accredited investor" within the meaning of Rule 501(a)
of Regulation D promulgated under the Securities Act, (ii) experienced in making
investments of the kind contemplated by this Agreement, (iii) capable, by reason
of its business and financial experience, of evaluating the relative merits and
risks of an investment in the Securities, and (iv) able to afford the loss of
its investment in the Securities.

     D. Buyer understands that the Securities are being offered and sold by the
Company in reliance on an exemption from the registration requirements of the
Securities Act and equivalent state securities and "blue sky" laws, and that the
Company is relying upon the accuracy of, and Buyer's compliance with, Buyer's
representations, warranties and covenants set forth in this Agreement to
determine the availability of such exemption and the eligibility of Buyer to
purchase the Securities;

     E. Buyer understands that the Securities have not been approved or
disapproved by the SEC or any state or provincial securities commission.

     F. This Agreement has been duly and validly authorized, executed and
delivered by Buyer and is a valid and binding agreement of Buyer enforceable
against it in accordance with its terms, subject to applicable bankruptcy,
insolvency, fraudulent conveyance, reorganization, moratorium and similar laws
affecting creditors' rights and remedies generally and except as rights to
indemnity and contribution may be limited by federal or state securities laws or
the public policy underlying such laws.

     II.  THE COMPANY'S REPRESENTATIONS

The Company represents and warrants to Buyer that:

     A.   Capitalization.

          1. The capitalization of the Company is accurately set forth on
Schedule III.A.1.

          2. The Conversion Shares and the Warrant Shares have been duly and
validly authorized and reserved for issuance by the Company, and, when issued by
the Company upon conversion of the Debenture and exercise of the Warrant, will
be duly and validly issued, fully paid and nonassessable and will not subject
the holder thereof to personal liability by reason of being such holder.

          3. Except as disclosed on Schedule III.A.3., there are no preemptive,
subscription, "call," right of first refusal or other similar rights to acquire
any capital stock of the Company or other voting securities of the Company that
have been issued or granted to any person and no other obligations of the
Company to issue, grant, extend or enter into any security, option, warrant,
"call," right, commitment, agreement, arrangement or undertaking with respect to
any of their respective capital stock.

     B.   Organization; Reporting Company Status.

          1. The Company is a corporation duly organized, validly existing and
in good standing under the laws of the state or jurisdiction in which it is
incorporated and is duly qualified as a foreign corporation in all jurisdictions
in which the failure so to qualify would reasonably be expected to have a
material adverse effect on the business, properties, prospects, condition
(financial or otherwise) or results of operations of the Company or on the
consummation of any of the transactions contemplated by this Agreement (a
"Material Adverse Effect").

                                       2
<PAGE>

          2. The Company is subject to the reporting requirements of the
Securities Exchange Act of 1934, as amended (the "Exchange Act"). The Common
Stock is listed on the National Association of Securities Dealers, Inc.
Over-The-Counter Bulletin Board ("OTCBB") and the Company has not received any
notice regarding, and to its knowledge there is no threat of, the termination or
discontinuance of the eligibility of the Common Stock for such listing.

     C. Authorization. The Company (i) has duly and validly authorized and
reserved for issuance shares of Common Stock, which is a number sufficient for
the conversion of the Debenture and the exercise of the Warrant and (ii) at all
times from and after the date hereof shall have a sufficient number of shares of
Common Stock duly and validly authorized and reserved for issuance to satisfy
the conversion of the Debenture in full and the exercise of the Warrant. The
Company understands and acknowledges the potentially dilutive effect on the
Common Stock of the issuance of the Conversion Shares and the Warrant Shares.
The Company further acknowledges that its obligation to issue Conversion Shares
upon conversion of the Debenture and Warrant Shares upon exercise of the Warrant
in accordance with this Agreement is absolute and unconditional regardless of
the dilutive effect that such issuance may have on the ownership interests of
other stockholders of the Company and notwithstanding the commencement of any
case under 11 U.S.C. ss. 101 et seq. (the "Bankruptcy Code"). In the event the
Company is a debtor under the Bankruptcy Code, the Company hereby waives to the
fullest extent permitted any rights to relief it may have under 11 U.S.C. ss.
362 in respect of the conversion of the Debenture and Warrants. The Company
agrees, without cost or expense to Buyer, to take or consent to any and all
action necessary to effectuate relief under 11 U.S.C. ss. 362.

     Authority; Validity and Enforceability. The Company has the requisite
corporate power and authority to enter into the Documents (as such term is
hereinafter defined) and to perform all of its obligations hereunder and
thereunder (including the issuance, sale and delivery to Buyer of the
Securities). The execution, delivery and performance by the Company of the
Documents and the consummation by the Company of the transactions contemplated
hereby and thereby (including, without limitation, the issuance of the Debenture
and the Warrant and the issuance and reservation for issuance of the Conversion
Shares and the Warrant Shares) have been duly and validly authorized by all
necessary corporate action on the part of the Company. Each of the Documents has
been duly and validly executed and delivered by the Company and each Document
constitutes a valid and binding obligation of the Company enforceable against it
in accordance with its terms, subject to applicable bankruptcy, insolvency,
fraudulent conveyance, reorganization, moratorium and similar laws affecting
creditors' rights and remedies generally and except as rights to indemnity and
contribution may be limited by federal or state securities laws or the public
policy underlying such laws. The Securities have been duly and validly
authorized for issuance by the Company and, when executed and delivered by the
Company, will be valid and binding obligations of the Company enforceable
against it in accordance with their respective terms, subject to applicable
bankruptcy, insolvency, fraudulent conveyance, reorganization, moratorium and
similar laws affecting creditors' rights and remedies generally. For purposes of
this Agreement, the term "Documents" means (i) this Agreement, including
schedules; (ii) the Registration Rights Agreement dated as of even date herewith
between the Company and Buyer substantially in the form attached hereto as
Exhibit C (the "Registration Rights Agreement"), (iii) the Debenture
substantially in the form attached hereto as Exhibit A; and (iv) the Warrant,
substantially in the form attached hereto as Exhibit B.

                                       3
<PAGE>

     Validity of Issuance of the Securities. The Securities will be validly
issued and outstanding, fully paid and nonassessable, and not subject to any
preemptive rights, rights of first refusal, tag-along rights, drag-along rights
or other similar rights.

     Non-contravention. The execution and delivery by the Company of the
Documents, the issuance of the Securities, and the consummation by the Company
of the other transactions contemplated hereby and thereby do not, and compliance
with the provisions of this Agreement and other Documents will not, conflict
with, or result in any violation of, or default (with or without notice or lapse
of time, or both) under, or give rise to a right of termination, cancellation or
acceleration of any obligation or loss of a material benefit under, or result in
the creation of any Lien (as such term is hereinafter defined) upon any of the
properties or assets of the Company or any of its Subsidiaries (as such term is
defined in the Debenture) under, or result in the termination of, or require
that any consent be obtained or any notice be given with respect to (i) the
Articles or Certificate of Incorporation or By-Laws of the Company or the
comparable charter or organizational documents of any of its Subsidiaries, in
each case as amended to the date of this Agreement, (ii) any loan or credit
agreement, debenture, bond, mortgage, indenture, lease, contract or other
agreement, instrument or permit applicable to the Company or any of its
Subsidiaries or their respective properties or assets or (iii) any Law (as such
term is hereinafter defined) applicable to, or any judgment, decree or order of
any court or government body having jurisdiction over, the Company or any of its
Subsidiaries or any of their respective properties or assets.

     Approvals. No authorization, approval or consent of any court or public or
governmental authority is required to be obtained by the Company for the
issuance and sale of the Securities to Buyer as contemplated by this Agreement,
except such authorizations, approvals and consents as have been obtained by the
Company prior to the date hereof.

     D. SEC Filings. The Company has properly and timely filed with the SEC all
reports, proxy statements, forms and other documents required to be filed with
the SEC under the Securities Act and the Exchange Act since becoming subject to
such Acts (the "SEC Filings"). As of their respective dates, (i) the SEC Filings
complied in all material respects with the requirements of the Securities Act or
the Exchange Act, as the case may be, and the rules and regulations of the SEC
promulgated thereunder applicable to such SEC Filings and (ii) none of the SEC
Filings contained at the time of its filing any untrue statement of a material
fact or omitted to state a material fact required to be stated therein or
necessary in order to make the statements therein, in light of the circumstances
under which they were made, not misleading. The financial statements of the
Company included in the SEC Filings, as of the dates of such documents, were
true and complete in all material respects and complied with applicable
accounting requirements and the published rules and regulations of the SEC with
respect thereto, were prepared in accordance with generally accepted accounting
principles in the United States ("GAAP") (except in the case of unaudited
financial statements permitted by Form 10-QSB under the Exchange Act) applied on
a consistent basis during the periods involved (except as may be indicated in
the notes thereto) and fairly presented the consolidated financial position of
the Company and its Subsidiaries as of the dates thereof and the consolidated
results of their operations and cash flows for the periods then ended (subject,
in the case of unaudited statements, to normal year-end audit adjustments that
in the aggregate are not material and to any other adjustment described
therein).

                                       4
<PAGE>

     E. Full Disclosure. Buyer hereby acknowledges receipt of the Company's
annual report on From 10-KSB for its fiscal year ended December 31, 2003 and its
quarterly reports on Form 10-QSB for the last three quarters ended March 31,
2003, June 30, 2003 and September 30, 2003. Since September 30, 2033, there is
no fact known to the Company (other than general economic or industry conditions
known to the public generally) that has not been fully disclosed in the SEC
Filings (including the aforementioned annual report and quarterly reports) that
(i) reasonably could be expected to have a Material Adverse Effect or (ii)
reasonably could be expected to materially and adversely affect the ability of
the Company to perform its obligations pursuant to the Documents, except as set
forth on Schedule III.B.I.

     F. Absence of Events of Default. No "Event of Default" (as such term
isdefined in the Debenture) and no event which, with notice, lapse of time or
both, would constitute an Event of Default (as so defined), has occurred and is
continuing.

     G. Securities Law Matters. Assuming the accuracy of the representations and
warranties of Buyer set forth in Article II, the offer and sale by the Company
of the Securities is exempt from (i) the registration and prospectus delivery
requirements of the Securities Act and the rules and regulations of the SEC
thereunder and (ii) the registration and/or qualification provisions of all
applicable state and provincial securities and "blue sky" laws. The Company
shall not directly or indirectly take, and shall not permit any of its
directors, officers or affiliates, as such term is defined in Rule 501(b) of
Regulation D under the Securities Act ("Affiliate")directly or indirectly to
take, any action (including, without limitation, any offering or sale to any
person or entity of any security similar to the Debenture) which will make
unavailable the exemption from Securities Act registration being relied upon by
the Company for the offer and sale to Buyer of the Debenture, the Conversion
Shares, the Warrant and the Warrant Shares as contemplated by this Agreement. No
form of general solicitation or advertising has been used or authorized by the
Company or any of its officers, directors or Affiliates in connection with the
offer or sale of the Securities as contemplated by this Agreement or any other
agreement to which the Company is a party.

     H. Registration Rights. Except as set forth on Schedule III.L., no Person
(as such term is defined in the Debenture) has, and as of the Closing Date (as
such term is hereinafter defined), no Person shall have, any demand,
"piggy-back" or other rights to cause the Company to file any registration
statement under the Securities Act relating to any of its securities or to
participate in any such registration statement.

     I. Interest. The timely payment of interest on the Debenture is not
prohibited by the Articles or Certificate of Incorporation or By-Laws of the
Company, in each case as amended to the date of this Agreement, or any
agreement, contract, document or other undertaking to which the Company is a
party.

     J. No Misrepresentation. No representation or warranty of the Company
contained in this Agreement or any of the other Documents, any schedule, annex
or exhibit hereto or thereto or any agreement, instrument or certificate
furnished by the Company to Buyer pursuant to this Agreement contains any untrue
statement of a material fact or omits to state a material fact required to be
stated therein or necessary to make the statements therein not misleading.

     K. Finder's Fee. There is no finder's fee, brokerage commission or like
payment in connection with the transactions contemplated by this Agreement for
which Buyer is liable or responsible.

                                       5
<PAGE>

     III. CERTAIN COVENANTS AND ACKNOWLEDGMENTS

     A. Filings. The Company shall make all necessary SEC Filings and "blue sky"
filings required to be made by the Company in connection with the sale of the
Securities to Buyer as required by all applicable Laws, and shall provide a copy
thereof to Buyer promptly after such filing.

     B. Reporting Status. So long as Buyer beneficially owns any of the
Securities, the Company shall timely file all reports required to be filed by it
with the SEC pursuant to Section 13 or 15(d) of the Exchange Act.

     C. Listing. Except to the extent the Company lists its Common Stock on The
New York Stock Exchange, The American Stock Exchange or The Nasdaq Stock Market,
the Company shall use its best efforts to maintain its listing of the Common
Stock on the OTCBB. If the Common Stock is delisted from OTCBB, the Company will
use its best efforts to list the Common Stock on the most liquid national
securities exchange or quotation system that the Common Stock is qualified to be
listed on.

     D. Reserved Conversion Common Stock. The Company at all times from and
after the date hereof shall have such number of shares of Common Stock duly and
validly authorized and reserved for issuance as shall be sufficient for the
conversion in full of the Debenture and the exercise of the Warrant.

     E. Information. Each of the parties hereto acknowledges and agrees that
Buyer shall not be provided with, nor be given access to, any material
non-public information relating to the Company.

     F. Accounting and Reserves. The Company shall maintain a standard and
uniform system of accounting and shall keep proper books and records and
accounts in which full, true, and correct entries shall be made of its
transactions, all in accordance with GAAP applied on consistent basis through
all periods, and shall set aside on such books for each fiscal year all such
reserves for depreciation, obsolescence, amortization, bad debts and other
purposes in connection with its operations as are required by such principles so
applied.

     G. Transactions with Affiliates. So long as the Debenture is outstanding,
neither the Company nor any of its Subsidiaries shall, directly or indirectly,
enter into any material transaction or agreement with any stockholder, officer,
director or Affiliate of the Company or family member of any officer, director
or Affiliate of the Company, unless the transaction or agreement is (i) reviewed
and approved by a majority of Disinterested Directors (as such term is
hereinafter defined) and (ii) on terms no less favorable to the Company or the
applicable Subsidiary than those obtainable from a nonaffiliated person. A
"Disinterested Director" shall mean a director of the Company who is not and has
not been an officer or employee of the Company and who is not a member of the
family of, controlled by or under common control with, any such officer or
employee.

     H. Certain Restrictions. So long as the Debenture is outstanding, no
dividends shall be declared or paid or set apart for payment nor shall any other
distribution be declared or made upon any capital stock of the Company, nor
shall any capital stock of the Company be redeemed, purchased or otherwise
acquired (other than a redemption, purchase or other acquisition of shares of
Common Stock made for purposes of an employee incentive or benefit plan
(including a stock option plan) of the Company or pursuant to any of the
security agreements listed on Schedule III.A, for any consideration by the
Company, directly or indirectly, nor shall any moneys be paid to or made
available for a sinking fund for the redemption of any Common Stock of any such
stock.

                                       6
<PAGE>

     I. Short Selling. So long as the Debenture is outstanding, Buyer agrees and
covenants on its behalf and on behalf of its Affiliates that neither Buyer nor
its Affiliates shall at any time engage in any short sales with respect to the
Company's Common Stock, or sell put options or similar instruments with respect
to the Company's Common Stock.

     IV.  ISSUANCE OF COMMON STOCK

     A. The Company undertakes and agrees that no instruction other than the
instructions referred to in this Article V and customary stop transfer
instructions prior to the registration and sale of the Common Stock pursuant to
an effective Securities Act registration statement shall be given to its
transfer agent for the Conversion Shares and the Warrant Shares and that the
Conversion Shares and the Warrant Shares shall otherwise be freely transferable
on the books and records of the Company as and to the extent provided in this
Agreement, the Registration Rights Agreement and applicable law. Nothing
contained in this Section V.A. shall affect in any way Buyer's obligations and
agreement to comply with all applicable securities laws upon resale of such
Common Stock.

     B. Buyer shall have the right to convert the Debenture and exercise the
Warrant by telecopying an executed and completed Conversion Notice (as such term
is defined in the Debenture) or Warrant Notice of Exercise (as such term is
defined in the Warrant) to the Company. Each date on which a Conversion Notice
or Warrant Notice of Exercise is telecopied to and received by the Company in
accordance with the provisions hereof shall be deemed a Conversion Date (as such
term is defined in the Debenture or the Warrant, as the case may be). The
Company shall cause the transfer agent to transmit the certificates evidencing
the Common Stock issuable upon conversion of the Debenture (together with a new
debenture, if any, representing the principal amount of the Debenture not being
so converted) or exercise of the Warrant (together with a new Warrant, if any,
representing the amount of the Warrant not being so exercised) to Buyer via
express courier, or if a Registration Statement covering the Common Stock has
been declared effective by the SEC by electronic transfer, within three (3)
business days after receipt by the Company of the Conversion Notice or Warrant
Notice of Exercise (the "Delivery Date").

     C. Upon the conversion of the Debenture or exercise of the Warrant or part
thereof, the Company shall, at its own cost and expense, take all necessary
action (including the issuance of an opinion of counsel) to assure that the
Company's transfer agent shall issue stock certificates in the name of Buyer (or
its nominee) or such other persons as designated by Buyer and in such
denominations to be specified at conversion or exercise, as the case may be,
representing the number of shares of Common Stock issuable upon such conversion
or exercise. The Company warrants that the Conversion Shares and Warrant Shares
will be unlegended, free-trading, and freely transferable, and will not contain
a legend restricting the resale or transferability of the Company Common Stock
provided the Conversion Shares and Warrant Shares are being sold pursuant to an
effective Registration Statement covering the Common Stock to be sold or is
otherwise exempt from registration when sold.

     D. The Company understands that a delay in the delivery of the Common Stock
in the form required pursuant to this section, or the Mandatory Redemption
Amount described in Section E hereof, beyond the Delivery Date or Mandatory
Redemption Payment Date (as hereinafter defined) could result in economic loss
to the Buyer. As compensation to the Buyer for such loss, the Company agrees to
pay late payments to the Buyer for late issuance of Common Stock in the form

                                       7
<PAGE>

required pursuant to Section C hereof upon conversion of the Debenture or late
payment of the Mandatory Redemption Amount, in the amount of $100 per business
day after the Delivery Date or Mandatory Redemption Payment Date, as the case
may be, for each $10,000 of Debenture principal amount being converted or
redeemed. The Company shall pay any payments incurred under this Section D in
immediately available funds upon demand. Furthermore, in addition to any other
remedies which may be available to the Buyer, in the event that the Company
fails for any reason to effect delivery of the Common Stock by the Delivery Date
or make payment by the Mandatory Redemption Payment Date, the Buyer will be
entitled to revoke all or part of the relevant Notice of Conversion or rescind
all or part of the notice of Mandatory Redemption by delivery of a notice to
such effect to the Company whereupon the Company and the Buyer shall each be
restored to their respective positions immediately prior to the delivery of such
notice, except that late payment charges described above shall be payable
through the date notice of revocation or rescission is given to the Company.

     E. Mandatory Redemption. In the event the Company is prohibited from
issuing Common Stock, or fails to timely deliver Common Stock on a Delivery
Date, or upon the occurrence of an Event of Default (as defined in the
Debenture) or for any reason other than pursuant to the limitations set forth
herein, then at the Buyer's election, the Company must pay to the Buyer ten (10)
business days after request by the Buyer or on the Delivery Date (if requested
by the Buyer) a sum of money determined by multiplying up to the outstanding
principal amount of the Debenture designated by the Buyer by 130%, together with
accrued but unpaid interest thereon ("Mandatory Redemption Payment"). The
Mandatory Redemption Payment must be received by the Buyer on the same date as
the Company Common Stock otherwise deliverable or within ten (10) business days
after request, whichever is sooner ("Mandatory Redemption Payment Date"). Upon
receipt of the Mandatory Redemption Payment, the corresponding Debenture
principal and interest will be deemed paid and no longer outstanding.

     F. Buy-In. In addition to any other rights available to the Buyer, if the
Company fails to deliver to the Buyer such Common Stock issuable upon conversion
of a Debenture by the Delivery Date and if ten (10) days after the Delivery Date
the Buyer purchases (in an open market transaction or otherwise) shares of
Common Stock to deliver in satisfaction of a sale by the Buyer of the Common
Stock which the Buyer anticipated receiving upon such conversion (a "Buy-In"),
then the Company shall pay in cash to the Buyer (in addition to any remedies
available to or elected by the Buyer) the amount by which (A) the Buyer's total
purchase price (including brokerage commissions, if any) for the shares of
Common Stock so purchased exceeds (B) the aggregate principal and/or interest
amount of the Debenture for which such conversion or exercise was not timely
honored, together with interest thereon at a rate of 15% per annum, accruing
until such amount and any accrued interest thereon is paid in full (which amount
shall be paid as liquidated damages and not as a penalty). For example, if the
Buyer purchases shares of Common Stock having a total purchase price of $11,000
to cover a Buy-In with respect to an attempted conversion of $10,000 of
Debenture principal and/or interest, the Company shall be required to pay the
Buyer $1,000, plus interest. The Buyer shall provide the Company written notice
indicating the amounts payable to the Buyer in respect of the Buy-In.

     G. The Securities shall be delivered by the Company to the Buyer pursuant
to Section I.B. hereof on a "delivery-against-payment basis" on the Closing
Date.

                                       8
<PAGE>

     V.   CLOSING DATE

     The Closing shall occur by the delivery: (i) to the Buyer of the
certificate evidencing the Debenture and all other Agreements, and (ii) to the
Company the Purchase Price.

     VI.  CONDITIONS TO THE COMPANY'S OBLIGATIONS

     Buyer understands that the Company's obligation to sell the Debenture and
Warrant on the Closing Date to Buyer pursuant to this Agreement is conditioned
upon:

     A. Delivery by Buyer to the Company and any other Person as indicated
herein, of the Purchase Price;

     B. The accuracy on the Closing Date of the representations and warranties
of Buyer contained in this Agreement as if made on the Closing Date (except for
representations and warranties which, by their express terms, speak as of and
relate to a specified date, in which case such accuracy shall be measured as of
such specified date) and the performance by Buyer in all material respects on or
before the Closing Date of all covenants and agreements of Buyer required to be
performed by it pursuant to this Agreement on or before the Closing Date; and

     C. There shall not be in effect any Law or order, ruling, judgment or writ
of any court or public or governmental authority restraining, enjoining or
otherwise prohibiting any of the transactions contemplated by this Agreement.

     VII. CONDITIONS TO BUYER'S OBLIGATIONS

     The Company understands that Buyer's obligation to purchase the Securities
on the Closing Date pursuant to this Agreement is conditioned upon:

     A. Delivery by the Company of the Debenture, the Warrant and the other
ancillary agreements (I/N/O Buyer or I/N/O Buyer's nominee);

     B. The accuracy on the Closing Date of the representations and warranties
of the Company contained in this Agreement as if made on the Closing Date
(except for representations and warranties which, by their express terms, speak
as of and relate to a specified date, in which case such accuracy shall be
measured as of such specified date) and the performance by the Company in all
respects on or before the Closing Date of all covenants and agreements of the
Company required to be performed by it pursuant to this Agreement on or before
the Closing Date, all of which shall be confirmed to Buyer by delivery of the
certificate of the chief executive officer of the Company to that effect;

     C. There not having occurred (i) any general suspension of trading in, or
limitation on prices listed for, the Common Stock on the NASD OTCBB, (ii) the
declaration of a banking moratorium or any suspension of payments in respect of
banks in the United States, (iii) the commencement of a war, armed hostilities
or other international or national calamity directly or indirectly involving the
United States or any of its territories, protectorates or possessions or (iv) in
the case of the foregoing existing at the date of this Agreement, a material
acceleration or worsening thereof;

     D. There not having occurred any event or development, and there being in
existence no condition, having or which reasonably and foreseeably could have a
Material Adverse Effect, except as set forth on Schedule VIII.D.;

                                       9
<PAGE>

     E. There shall not be in effect any Law, order, ruling, judgment or writ of
any court or public or governmental authority restraining, enjoining or
otherwise prohibiting any of the transactions contemplated by this Agreement;

     F. The Company shall have obtained all consents, approvals or waivers from
governmental authorities and third persons necessary for the execution, delivery
and performance of the Documents and the transactions contemplated thereby, all
without material cost to the Company;

     G. Buyer shall have received such additional documents, certificates,
payment, assignments, transfers and other deliveries as it or its legal counsel
may reasonably request and as are customary to effect a closing of the matters
herein contemplated;

     I. Delivery by the Company of an enforceability opinion from its outside
counsel in form and substance satisfactory to Buyer

     VIII. SURVIVAL; INDEMNIFICATION

     A. The representations, warranties and covenants made by each of the
Company and Buyer in this Agreement, the annexes, schedules and exhibits hereto
and in each instrument, agreement and certificate entered into and delivered by
them pursuant to this Agreement shall survive the Closing Date and the
consummation of the transactions contemplated hereby. In the event of a breach
or violation of any of such representations, warranties or covenants, the party
to whom such representations, warranties or covenants have been made shall have
all rights and remedies for such breach or violation available to it under the
provisions of this Agreement or otherwise, whether at law or in equity,
irrespective of any investigation made by or on behalf of such party on or prior
to the Closing Date.

     B. The Company hereby agrees to indemnify and hold harmless Buyer, its
Affiliates and their respective officers, directors, partners and members
(collectively, the "Buyer Indemnitees") from and against any and all losses,
claims, damages, judgments, penalties, liabilities and deficiencies
(collectively, "Losses") and agrees to reimburse Buyer Indemnitees for all
out-of-pocket expenses (including the fees and expenses of legal counsel), in
each case promptly as incurred by Buyer Indemnitees and to the extent arising
out of or in connection with:

          1. any misrepresentation, omission of fact or breach of any of the
     Company's representations or warranties contained in this Agreement or the
     other Documents, or the annexes, schedules or exhibits hereto or thereto or
     any instrument, agreement or certificate entered into or delivered by the
     Company pursuant to this Agreement or the other Documents;

          2. any failure by the Company to perform any of its covenants,
     agreements, undertakings or obligations set forth in this Agreement or the
     other Documents or any instrument, certificate or agreement entered into or
     delivered by the Company pursuant to this Agreement or the other Documents;

          3. the purchase of the Debenture, the conversion of the Debenture, the
     payment of interest on the Debenture, the purchase of the Warrants, the
     issuance of the Warrant Shares, the consummation of the transactions
     contemplated by this Agreement and the other Documents, the use of any of
     the proceeds of the Purchase Price by the Company, the purchase or
     ownership of any or all of the Securities, the performance by the parties
     hereto of their respective obligations hereunder and under the Documents or
     any claim, litigation, investigation, proceedings or governmental action
     relating to any of the foregoing, whether or not Buyer is a party thereto;
     or

                                       10
<PAGE>

          4. resales of the Common Stock by Buyer in the manner and as
     contemplated by this Agreement and the Registration Rights Agreement.

     C. Buyer hereby agrees to indemnify and hold harmless the Company, its
Affiliates and their respective officers, directors, partners and members
(collectively, the "Company Indemnitees") from and against any and all Losses,
and agrees to reimburse the Company Indemnitees for all out-of-pocket expenses
(including the fees and expenses of legal counsel), in each case promptly as
incurred by the Company Indemnitees and to the extent arising out of or in
connection with:

          1. any misrepresentation, omission of fact or breach of any of Buyer's
     representations or warranties contained in this Agreement or the other
     Documents, or the annexes, schedules or exhibits hereto or thereto or any
     instrument, agreement or certificate entered into or delivered by Buyer
     pursuant to this Agreement or the other Documents; or

          2. any failure by Buyer to perform in any material respect any of its
     covenants, agreements, undertakings or obligations set forth in this
     Agreement or the other Documents or any instrument, certificate or
     agreement entered into or delivered by Buyer pursuant to this Agreement or
     the other Documents.

     D. Promptly after receipt by either party hereto seeking indemnification
pursuant to this Article VIII (an "Indemnified Party") of written notice of any
investigation, claim, proceeding or other action in respect of which
indemnification is being sought (each, a "Claim"), the Indemnified Party
promptly shall notify the party against whom indemnification pursuant to this
Article VIII is being sought (the "Indemnifying Party") of the commencement
thereof, but the omission so to notify the Indemnifying Party shall not relieve
it from any liability that it otherwise may have to the Indemnified Party except
to the extent that the Indemnifying Party is materially prejudiced and forfeits
substantive rights or defenses by reason of such failure. In connection with any
Claim as to which both the Indemnifying Party and the Indemnified Party are
parties, the Indemnifying Party shall be entitled to assume the defense thereof.
Notwithstanding the assumption of the defense of any Claim by the Indemnifying
Party, the Indemnified Party shall have the right to employ separate legal
counsel and to participate in the defense of such Claim, and the Indemnifying
Party shall bear the reasonable fees, out-of-pocket costs and expenses of such
separate legal counsel to the Indemnified Party if (and only if): (x) the
Indemnifying Party shall have agreed to pay such fees, out-of-pocket costs and
expenses, (y) the Indemnified Party and the Indemnifying Party reasonably shall
have concluded that representation of the Indemnified Party and the Indemnifying
Party by the same legal counsel would not be appropriate due to actual or, as
reasonably determined by legal counsel to the Indemnified Party, potentially
differing interests between such parties in the conduct of the defense of such
Claim, or if there may be legal defenses available to the Indemnified Party that
are in addition to or disparate from those available to the Indemnifying Party
or (z) the Indemnifying Party shall have failed to employ legal counsel
reasonably satisfactory to the Indemnified Party within a reasonable period of
time after notice of the commencement of such Claim. If the Indemnified Party
employs separate legal counsel in circumstances other than as described in
clauses (x), (y) or (z) above, the fees, costs and expenses of such legal
counsel shall be borne exclusively by the Indemnified Party. Except as provided
above, the Indemnifying Party shall not, in connection with any Claim in the
same jurisdiction, be liable for the fees and expenses of more than one firm of
legal counsel for the Indemnified Party (together with appropriate local
counsel). The Indemnifying Party shall not, without the prior written consent of
the Indemnified Party (which consent shall not unreasonably be withheld), settle
or compromise any Claim or consent to the entry of any judgment that does not
include an unconditional release of the Indemnified Party from all liabilities
with respect to such Claim or judgment.

                                       11
<PAGE>

     E. In the event one party hereunder should have a claim for indemnification
that does not involve a claim or demand being asserted by a third party, the
Indemnified Party promptly shall deliver notice of such claim to the
Indemnifying Party. If the Indemnified Party disputes the claim, such dispute
shall be resolved by mutual agreement of the Indemnified Party and the
Indemnifying Party or by binding arbitration conducted in accordance with the
procedures and rules of the American Arbitration Association. Judgment upon any
award rendered by any arbitrators may be entered in any court having competent
jurisdiction thereof.

     IX.  GOVERNING LAW

     This Agreement shall be governed by and interpreted in accordance with the
laws of the State of California, without regard to the conflicts of law
principles of such state.

     X.   SUBMISSION TO JURISDICTION

     Each of the parties hereto consents to the exclusive jurisdiction of the
federal courts whose districts encompass any part of the City of San Diego or
the state courts of the State of California sitting in the City of San Diego in
connection with any dispute arising under this Agreement and the other
Documents. Each party hereto hereby irrevocably and unconditionally waives, to
the fullest extent it may effectively do so, any defense of an inconvenient
forum or improper venue to the maintenance of such action or proceeding in any
such court and any right of jurisdiction on account of its place of residence or
domicile. Each party hereto irrevocably and unconditionally consents to the
service of any and all process in any such action or proceeding in such courts
by the mailing of copies of such process by registered or certified mail (return
receipt requested), postage prepaid, at its address specified in Article XVII.
Each party hereto agrees that a final judgment in any such action or proceeding
shall be conclusive and may be enforced in other jurisdictions by suit on the
judgment or in any other manner provided by law.

     XI.  WAIVER OF JURY TRIAL

     TO THE FULLEST EXTENT PERMITTED BY LAW, EACH OF THE PARTIES HERETO HEREBY
KNOWINGLY, VOLUNTARILY AND INTENTIONALLY WAIVES ITS RESPECTIVE RIGHTS TO A JURY
TRIAL OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF THIS
AGREEMENT OR ANY OTHER DOCUMENT OR ANY DEALINGS BETWEEN THEM RELATING TO THE
SUBJECT MATTER OF THIS AGREEMENT AND OTHER DOCUMENTS. EACH PARTY HERETO (i)
CERTIFIES THAT NEITHER OF THEIR RESPECTIVE REPRESENTATIVES, AGENTS OR ATTORNEYS
HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH PARTY WOULD NOT, IN THE EVENT
OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVERS AND (ii) ACKNOWLEDGES THAT
IT HAS BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE
MUTUAL WAIVERS AND CERTIFICATIONS HEREIN.

                                       12
<PAGE>

     XII. COUNTERPARTS; EXECUTION

     This Agreement may be executed in counterparts, each of which when so
executed and delivered shall be an original, but both of which counterparts
shall together constitute one and the same instrument. A facsimile transmission
of this signed Agreement shall be legal and binding on both parties hereto.

     XIII. HEADINGS

     The headings of this Agreement are for convenience of reference and shall
not form part of, or affect the interpretation of, this Agreement.

     XIV. SEVERABILITY

     In the event any one or more of the provisions contained in this Agreement
or in the other Documents should be held invalid, illegal or unenforceable in
any respect, the validity, legality and enforceability of the remaining
provisions contained herein or therein shall not in any way be affected or
impaired thereby. The parties shall endeavor in good-faith negotiations to
replace the invalid, illegal or unenforceable provisions with valid provisions,
the economic effect of which comes as close as possible to that of the invalid,
illegal or unenforceable provisions.

     XV.  ENTIRE AGREEMENT; REMEDIES, AMENDMENTS AND WAIVERS

     This Agreement and the Documents constitute the entire agreement between
the parties hereto pertaining to the subject matter hereof and supersede all
prior agreements, understandings, negotiations and discussions, whether oral or
written, of such parties. No supplement, modification or waiver of this
Agreement shall be binding unless executed in writing by both parties. No waiver
of any of the provisions of this Agreement shall be deemed or shall constitute a
waiver of any other provision hereof (whether or not similar), nor shall such
waiver constitute a continuing waiver unless otherwise expressly provided.

     XVI. NOTICES

     Except as may be otherwise provided herein, any notice or other
communication or delivery required or permitted hereunder shall be in writing
and shall be delivered personally, or sent by telecopier machine or by a
nationally recognized overnight courier service, and shall be deemed given when
so delivered personally, or by telecopier machine or overnight courier service
as follows:

     A.   if to the Company, to:

          Integrated Surgical Systems, Inc.
          1850 Research Park Drive
          Davis, CA 95616
          Telephone:        530-792-2600
          Facsimile:        530-792-2690

          With a copy to:

          Snow Becker Krauss P.C.
          605 Third Avenue
          New York, NY 10158
          Telephone:        212-687-3860
          Facsimile:        212-455-0331


                                       13
<PAGE>

     B.   if to Buyer, to:

          Golden Gate Investors, Inc.
          7817 Herschel Avenue, Suite 200
          La Jolla, California 92037
          Telephone:        858-551-8789
          Facsimile:        858-551-8779

The Company or Buyer may change its foregoing address by notice given pursuant
to this Article XVII.

     XVII. CONFIDENTIALITY

     Each of the Company and Buyer agrees to keep confidential and not to
disclose to or use for the benefit of any third party the terms of this
Agreement or any other information which at any time is communicated by the
other party as being confidential without the prior written approval of the
other party; provide, however, that this provision shall not apply to
information which, at the time of disclosure, is already part of the public
domain (except by breach of this Agreement) and information which is required to
be disclosed by law (including, without limitation, pursuant to Item 601(b)(10)
of Regulation S-K under the Securities Act and the Exchange Act).

     XVIII. ASSIGNMENT

     This Agreement shall not be assignable by either of the parties hereto
prior to the Closing without the prior written consent of the other party, and
any attempted assignment contrary to the provisions hereby shall be null and
void; provided, however, that Buyer may assign its rights and obligations
hereunder, in whole or in part, to any Affiliate of Buyer.

     IN WITNESS WHEREOF, the parties hereto have duly caused this Agreement to
be executed and delivered on the date first above written.


Integrated Surgical Systems, Inc.               Golden Gate Investors, Inc.

By: /s/ RAMESH C. TRIVEDI                       By: /s/ TRAVIS W. HUFF
    ---------------------------                     ---------------------------
    Ramesh C. Trivedi                               Travis W. Huff,
    President and CEO                               Portfolio Manager





                                       14
- ------------------------                               -------------------------
Initials                                                                Initials

<PAGE>

                                 SCHEDULE III.L.

                               REGISTRATION RIGHTS

     Name


</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-31.1
<SEQUENCE>5
<FILENAME>iss31-1.txt
<DESCRIPTION>CERTIFICATION
<TEXT>

Exhibit 31.1

                                  CERTIFICATION

I, Ramesh C. Trivedi, Chief Executive Officer of Integrated Surgical Systems,
Inc., certify that:

1.   I have reviewed this Quarterly Report on Form 10-QSB for the quarter ended
     June 30, 2004 of Integrated Surgical Systems, Inc.;

2.   Based on my knowledge, this report does not contain any untrue statement of
     a material fact or omit to state a material fact necessary to make the
     statements made, in light of the circumstances under which such statements
     were made, not misleading with respect to the period covered by this
     report;

3.   Based on my knowledge, the financial statements, and other financial
     information included in this report, fairly present in all material
     respects the financial condition, results of operations and cash flows of
     the small business issuer as of, and for, the periods presented in this
     report;

4.   The small business issuer's other certifying officers and I are responsible
     for establishing and maintaining disclosure controls and procedures (as
     defined in Exchange Act Rules 13a-15(e) and 15d-15(e) for the small
     business issue and have:

     (a)  Designed such disclosure controls and procedures, or caused such
          disclosure controls and procedures to be designed under our
          supervision, to ensure that material information relating to the small
          business issuer, including its consolidated subsidiaries, is made
          known to us by others within those entities, particularly during the
          period in which this report is being prepared;

     (b)  Evaluated the effectiveness of the small business issuer's disclosure
          controls and procedures and presented in this report our conclusion
          about the effectiveness of the disclosure controls and procedures, as
          of the end of the period covered by this report based on such
          evaluation; and

     (c)  Disclosed in this report any change in the small business issuer's
          internal control over financial reporting that occurred during the
          small business issuer's most recent fiscal quarter (the small business
          issuer's fourth quarter in the case of an annual report) that has
          materially affected, or is reasonably likely to materially affect, the
          small business issuer's internal control over financial reporting; and

5.   The small business issuer's other certifying officer(s) and I have
     disclosed, based on our most recent evaluation of internal control over
     financial reporting, to the small business issuer's auditors and the audit
     committee of the small business issuer's board of directors (or persons
     performing the equivalent functions):

     (a)  All significant deficiencies and material weakness in the design or
          operation of internal control over financial reporting which are
          reasonably likely to adversely affect the small business issuer's
          ability to record, process, summarize and report financial
          information; and

     (b)  Any fraud, whether or not material, that involves management or other
          employees who have a significant role in the registrant's internal
          control over financial reporting.



Date: November 24, 2004                  By: /s/ RAMESH C. TRIVEDI
                                         ---------------------------------------
                                         Ramesh C. Trivedi
                                         Chief Executive Officer


</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-31.2
<SEQUENCE>6
<FILENAME>iss60431-2.txt
<DESCRIPTION>CERTIFICATION
<TEXT>

Exhibit 31.2

                                  CERTIFICATION

I, Charles J. Novak, Chief Financial Officer of Integrated Surgical Systems,
Inc., certify that:

1.   I have reviewed this Quarterly Report on Form 10-QSB for the year quarter
     ended June 30, 2004 of Integrated Surgical Systems, Inc.;

2.   Based on my knowledge, this report does not contain any untrue statement of
     a material fact or omit to state a material fact necessary to make the
     statements made, in light of the circumstances under which such statements
     were made, not misleading with respect to the period covered by this
     report;

3.   Based on my knowledge, the financial statements, and other financial
     information included in this report, fairly present in all material
     respects the financial condition, results of operations and cash flows of
     the small business issuer as of, and for, the periods presented in this
     report;

4.   The small business issuer's other certifying officers and I are responsible
     for establishing and maintaining disclosure controls and procedures (as
     defined in Exchange Act Rules 13a-15(e) and 15d-15(e) for the small
     business issue and have:

     (a)  Designed such disclosure controls and procedures, or caused such
          disclosure controls and procedures to be designed under our
          supervision, to ensure that material information relating to the small
          business issuer, including its consolidated subsidiaries, is made
          known to us by others within those entities, particularly during the
          period in which this report is being prepared;

     (b)  Evaluated the effectiveness of the small business issuer's disclosure
          controls and procedures and presented in this report our conclusion
          about the effectiveness of the disclosure controls and procedures, as
          of the end of the period covered by this report based on such
          evaluation; and

     (c)  Disclosed in this report any change in the small business issuer's
          internal control over financial reporting that occurred during the
          small business issuer's most recent fiscal quarter (the small business
          issuer's fourth quarter in the case of an annual report) that has
          materially affected, or is reasonably likely to materially affect, the
          small business issuer's internal control over financial reporting; and

5.   The small business issuer's other certifying officer(s) and I have
     disclosed, based on our most recent evaluation of internal control over
     financial reporting, to the small business issuer's auditors and the audit
     committee of the small business issuer's board of directors (or persons
     performing the equivalent functions):

     (a)  All significant deficiencies and material weakness in the design or
          operation of internal control over financial reporting which are
          reasonably likely to adversely affect the small business issuer's
          ability to record, process, summarize and report financial
          information; and

     (b)  Any fraud, whether or not material, that involves management or other
          employees who have a significant role in the registrant's internal
          control over financial reporting.



Date: November 24, 2004                   By: /s/ CHARLES J. NOVAK
                                          ----------------------------------
                                          Charles J. Novak
                                          Chief Financial Officer


</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-32.1
<SEQUENCE>7
<FILENAME>iss32-1.txt
<DESCRIPTION>CERTIFICATION
<TEXT>

Exhibit 32.1

                                  CERTIFICATION



I I, Ramesh C. Trivedi, Chief Executive Officer of Integrated Surgical Systems,
Inc. (the "Company"), hereby certify, pursuant to 18 U.S.C. Section 1350, as
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

     1.   The Quarterly Report on Form 10-QSB of the Company for the quarter
          ended June 30, 2004, which this certification accompanies (the
          "Periodic Report"), fully complies with the requirements of Section
          13(a) of the Securities Exchange Act of 1934; and

     2.   The information contained in the Periodic Report fairly presents, in
          all material respects, the financial condition and results of
          operations of the Company.




Dated: November 24, 2004                     /s/ Ramesh C. Trivedi
                                             ---------------------
                                             Ramesh C. Trivedi
                                             Chief Executive Officer



</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-32.2
<SEQUENCE>8
<FILENAME>iss32-2.txt
<DESCRIPTION>CERTIFICATION
<TEXT>

Exhibit 32.2

                                  CERTIFICATION



I, Charles J. Novak, Chief Financial Officer of Integrated Surgical Systems,
Inc. (the "Company"), hereby certify, pursuant to 18 U.S.C. Section 1350, as
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

     1.   The Quarterly Report on Form 10-QSB of the Company for the quarter
          ended June 30, 2004, which this certification accompanies (the
          "Periodic Report"), fully complies with the requirements of Section
          13(a) of the Securities Exchange Act of 1934; and

     2.   The information contained in the Periodic Report fairly presents, in
          all material respects, the financial condition and results of
          operations of the Company.




Dated: November 24, 2004                     /s/ Charles J. Novak
                                             --------------------
                                             Charles J. Novak
                                             Chief Financial Officer







</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
