EX-16.1 2 v245364_ex16-1.htm EXHIBIT 16.1

January 12, 2012

Securities and Exchange Commission

Washington, D.C. 20549

Commissioners:

We have read Integrated Surgical Systems, Inc.’s statements included under Item 4.01 of its Form 8-K filed on January 12, 2012 and we agree with such statements concerning our firm.

/s/ SingerLewak LLP

SingerLewak LLP

Los Angeles, California