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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) | Common Stock [Member] | Common Stock [Member] $6.44 Common Stock Issuance [Member] | Common Stock [Member] $7.00 Common Stock Issuance [Member] | Common Stock [Member] $3.00 Common Stock Issuance [Member] | Common Stock [Member] $8.00 Common Stock Issuance [Member] | Common Stock [Member] $5.50 Common Stock Issuance [Member] | Common Stock [Member] Employees and Directors [Member] | Additional paid-in capital [Member] | Additional paid-in capital [Member] $6.44 Common Stock Issuance [Member] | Additional paid-in capital [Member] $7.00 Common Stock Issuance [Member] | Additional paid-in capital [Member] $3.00 Common Stock Issuance [Member] | Additional paid-in capital [Member] $8.00 Common Stock Issuance [Member] | Additional paid-in capital [Member] $5.50 Common Stock Issuance [Member] | Additional paid-in capital [Member] Employees and Directors [Member] | Accumulated deficit [Member] | Accumulated deficit [Member] $6.44 Common Stock Issuance [Member] | Accumulated deficit [Member] $7.00 Common Stock Issuance [Member] | Accumulated deficit [Member] $3.00 Common Stock Issuance [Member] | Accumulated deficit [Member] $8.00 Common Stock Issuance [Member] | Accumulated deficit [Member] $5.50 Common Stock Issuance [Member] | Accumulated deficit [Member] Employees and Directors [Member] | Total | $6.44 Common Stock Issuance [Member] | $7.00 Common Stock Issuance [Member] | $3.00 Common Stock Issuance [Member] | $8.00 Common Stock Issuance [Member] | $5.50 Common Stock Issuance [Member] | Employees and Directors [Member]
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Balance at Dec. 31, 2014 | $ 200,000 |  |  |  |  |  |  | $ 300,690,000 |  |  |  |  |  |  | $ (296,074,000) |  |  |  |  |  |  | $ 4,816,000 |  |  |  |  |  |
Balance (in shares) at Dec. 31, 2014 | 19,960,801 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued for services | $ 1,000 |  |  |  |  |  |  | 400,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 401,000 |  |  |  |  |  |
Common stock issued for services (in shares) | 105,177 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued to employees | $ 0 |  |  |  |  |  |  | 32,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 32,000 |  |  |  |  |  |
Common stock issued to employees (in shares) | 10,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restricted common stock issued |  |  |  |  |  |  | $ 13,000 |  |  |  |  |  |  | $ 4,807,000 |  |  |  |  |  |  | $ 0 |  |  |  |  |  |  | $ 4,820,000
Restricted common stock issued (in shares) |  |  |  |  |  |  | 1,350,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of $5.00 warrants | $ 9,000 |  |  |  |  |  |  | 4,626,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 4,635,000 |  |  |  |  |  |
Exercise of $5.00 warrants (in shares) | 927,119 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued, net of costs |  |  |  | $ 24,000 | $ 13,000 | $ 28,000 |  |  |  |  | $ 6,977,000 | $ 8,992,000 | $ 15,383,000 |  |  |  |  | $ 0 | $ 0 | $ 0 |  |  | $ 0 | $ 0 | $ 7,001,000 | $ 9,005,000 | $ 15,411,000 |
Common stock issued, net of costs (in shares) |  |  |  | 2,333,334 | 1,250,000 | 2,829,091 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued to Abeona Ohio holders | $ 40,000 |  |  |  |  |  |  | 31,718,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 31,758,000 |  |  |  |  |  |
Common stock issued to Abeona Ohio holders (in shares) | 3,979,761 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Transfer agent correction 2014 reverse stock split | $ 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |
Transfer agent correction 2014 reverse stock split (in shares) | (2,270) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock option compensation expense | $ 0 |  |  |  |  |  |  | 4,368,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 4,368,000 |  |  |  |  |  |
Net loss | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | (14,526,000) |  |  |  |  |  |  | (14,526,000) |  |  |  |  |  |
Balance at Dec. 31, 2015 | $ 328,000 |  |  |  |  |  |  | 377,993,000 |  |  |  |  |  |  | (310,600,000) |  |  |  |  |  |  | 67,721,000 |  |  |  |  |  |
Balance (in shares) at Dec. 31, 2015 | 32,743,013 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued for services | $ 8,000 |  |  |  |  |  |  | 2,444,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 2,452,000 |  |  |  |  |  |
Common stock issued for services (in shares) | 750,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Restricted common stock issued | $ 0 |  |  |  |  |  | $ 1,000 | 150,000 |  |  |  |  |  | $ 3,431,000 | 0 |  |  |  |  |  | $ 0 | 150,000 |  |  |  |  |  | $ 3,432,000
Restricted common stock issued (in shares) | 52,690 |  |  |  |  |  | 100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of $5.00 warrants | $ 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |
Exercise of $5.00 warrants (in shares) | 5,836 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued, net of costs |  | $ 2,000 | $ 63,000 |  |  |  |  |  | $ 967,000 | $ 41,005,000 |  |  |  |  |  | $ 0 | $ 0 |  |  |  |  |  | $ 969,000 | $ 41,068,000 | $ 0 | $ 0 | $ 0 |
Common stock issued, net of costs (in shares) |  | 158,029 | 6,293,889 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued for cash exercise of options | $ 1,000 |  |  |  |  |  |  | 349,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 350,000 |  |  |  |  |  |
Common stock issued for cash exercise of options (in shares) | 151,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock option compensation expense | $ 0 |  |  |  |  |  |  | 4,829,000 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | 4,829,000 |  |  |  |  |  |
Net loss | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  | (21,873,000) |  |  |  |  |  |  | (21,873,000) |  |  |  |  |  |
Balance at Dec. 31, 2016 | $ 403,000 |  |  |  |  |  |  | $ 431,168,000 |  |  |  |  |  |  | $ (332,473,000) |  |  |  |  |  |  | $ 99,098,000 |  |  |  |  |  |
Balance (in shares) at Dec. 31, 2016 | 40,254,457 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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