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Stock Based Compensation and Restricted Stock Compensation (Tables)
3 Months Ended
Mar. 31, 2017
Stock Options [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Summarization of stock-based compensation
The following table summarizes stock-based compensation for the three months ended March 31, 2017 and 2016:
 
  
Three months ended March 31,
 
  
2017
  
2016
 
Research and development
 
$
356,000
  
$
341,000
 
General and administrative
  
1,136,000
   
1,251,000
 
Stock-based compensation expense included in operating expense
 
$
1,492,000
  
$
1,592,000
 
Restricted Stock [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Summarization of stock-based compensation
The following table summarizes restricted common stock compensation expense for the three months ended March 31, 2017 and 2016:
 
  
Three months ended March 31,
 
  
2017
  
2016
 
Research and development
 
$
-
  
$
62,000
 
General and administrative  
362,000
   
1,830,000
 
Stock-based compensation expense included in operating expense
 
$
362,000
  
$
1,892,000