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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016
Revenues |  |
License revenues | $ 602,000 | $ 602,000
Royalties | 235,000 | 287,000
Total revenues | 837,000 | 889,000
Expenses |  |
Research and development | 16,989,000 | 10,655,000
General and administrative | 10,943,000 | 13,290,000
Depreciation and amortization | 741,000 | 825,000
Total expenses | 28,673,000 | 24,770,000
Loss from operations | (27,836,000) | (23,881,000)
Interest and miscellaneous income | 525,000 | 2,014,000
Interest and other expense | (8,000) | (6,000)
Total non operating income (expense) | 517,000 | 2,008,000
Net loss | $ (27,319,000) | $ (21,873,000)
Basic and diluted loss per common share (in dollars per share) | $ (0.66) | $ (0.64)
Weighted average number of common shares outstanding - basic and diluted (in shares) | 41,636,752 | 34,180,253

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