<SEC-DOCUMENT>0000914121-20-001562.txt : 20200422
<SEC-HEADER>0000914121-20-001562.hdr.sgml : 20200422
<ACCEPTANCE-DATETIME>20200422171748
ACCESSION NUMBER:		0000914121-20-001562
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20200422
DATE AS OF CHANGE:		20200422
GROUP MEMBERS:		DR. JEFFREY R. JAY, M.D.
GROUP MEMBERS:		MR. DAVID KROIN

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ABEONA THERAPEUTICS INC.
		CENTRAL INDEX KEY:			0000318306
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				830221517
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-33655
		FILM NUMBER:		20808578

	BUSINESS ADDRESS:	
		STREET 1:		1330 AVENUE OF THE AMERICAS, 33RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		646-813-4701

	MAIL ADDRESS:	
		STREET 1:		1330 AVENUE OF THE AMERICAS, 33RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PLASMATECH BIOPHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20140922

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ACCESS PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19960209

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CHEMEX PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GREAT POINT PARTNERS LLC
		CENTRAL INDEX KEY:			0001281446
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		165 MASON STREET, 3RD FLOOR
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
		BUSINESS PHONE:		203 971-3300

	MAIL ADDRESS:	
		STREET 1:		165 MASON STREET, 3RD FLOOR
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>gr54950685-sc13da1.htm
<DESCRIPTION>SCHEDULE 13D (AMENDMENT NO. 1)
<TEXT>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SECURITIES AND EXCHANGE COMMISSION</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">Washington, D.C. 20549</div>
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    <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">(Rule 13d-101)</div>
            <div style="text-align: center; font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">TO &#167; 240.13d-1(a) AND AMENDMENTS THERETO FILED</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">PURSUANT TO &#167; 240.13d-2(a)</div>
            <div style="text-align: center; font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">Under the Securities Exchange Act of 1934<br>
              (Amendment No. 1)*</div>
            <div><font style="font-family: 'Times New Roman';">&#160; </font>
              <hr noshade="noshade" align="center" style="height: 1px; width: 20%; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
            <div style="font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-size: 18pt; font-weight: bold; font-family: 'Times New Roman';">Abeona Therapeutics Inc.</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman';">(Name of Issuer)</div>
            <div style="text-align: center; font-family: 'Times New Roman';">&#160;</div>
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              <hr noshade="noshade" align="center" style="height: 1px; width: 20%; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
            <div style="text-align: center; font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">Common Stock, par value $0.01 per share</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman';">(Title of Class of Securities)</div>
            <div style="font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">00289Y107</div>
          </td>
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          <td style="width: 100%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 4px double rgb(0, 0, 0);">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman';">(CUSIP Number)</div>
            <div style="font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">Ron Panzier<br>
              Great Point Partners, LLC<br>
              165 Mason Street, 3<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">rd</sup> Floor<br>
              Greenwich, CT 06830<br>
              (203) 971-3300</div>
            <div style="font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">Copies to:</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">Richard M. Brand</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">Andrew Alin</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">Cadwalader, Wickersham &amp; Taft LLP</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">200 Liberty Street</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">New York, NY 10281</div>
            <div style="text-align: center; font-weight: bold; font-family: 'Times New Roman';">212-504-6000</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman';"> (Name, Address and Telephone Number of Person<br>
              Authorized to Receive Notices and Communications)</div>
            <div style="font-family: 'Times New Roman';">&#160;</div>
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">April 21, 2020</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman';">(Date of Event which Requires Filing of this Statement)</div>
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              <hr noshade="noshade" align="center" style="height: 1px; width: 20%; color: #000000; background-color: #000000; text-align: center; margin-left: auto; margin-right: auto; border: none;"></div>
            <div style="text-align: center; font-family: 'Times New Roman';">&#160;</div>
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    <div style="font-family: 'Times New Roman';">If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of &#167;&#167;240.13d-1(e), 240.13d-1(f)
      or 240.13d-1(g), check the following box.&#160;&#160;&#9744;</div>
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    <div><font style="font-weight: bold; font-family: 'Times New Roman';">Note</font><font style="font-family: 'Times New Roman';">: Schedule filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See
        &#167;240.13d-7 for other parties to whom copies are to be sent.</font></div>
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      </font> </div>
    <div><font style="font-weight: bold; font-family: 'Times New Roman';">*</font><font style="font-family: 'Times New Roman';">The remainder of this cover page shall be filled out for a reporting person&#8217;s initial filing on this form with respect to the
        subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.</font></div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="font-family: 'Times New Roman';">The information required in the remainder of this cover page shall not be deemed to be &#8220;filed&#8221; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&#8220;<u>Act</u>&#8221;) or otherwise subject to the
      liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).</div>
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            <div style="font-family: 'Times New Roman';">CUSIP No. <font style="color: #000000;">00289Y107</font></div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
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    <div style="font-family: 'Times New Roman';">&#160;</div>
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          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">1</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Name of Reporting Person<br>
              Great Point Partners, LLC</div>
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          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
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          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">2</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.21%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">(a)</div>
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          <td colspan="2" style="width: 80.91%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;<font style="color: #000000;">&#9744;</font></div>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.21%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">(b)</div>
          </td>
          <td colspan="2" style="width: 80.91%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;&#9744;</div>
          </td>
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            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">3</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">SEC Use Only</div>
          </td>
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          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
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          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">4</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Source of Funds (See Instructions)<br>
              AF</div>
          </td>
        </tr>
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          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
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          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">5</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)&#160; &#160;&#160;&#160;<font style="color: #000000;">&#9744;</font></div>
          </td>
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          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">6</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization<br>
              Delaware</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td colspan="3" rowspan="7" style="width: 13.34%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Number of<br>
              Shares<br>
              Beneficially<br>
              Owned by<br>
              Each<br>
              Reporting<br>
              Person With</div>
          </td>
          <td style="width: 4.94%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">7</div>
          </td>
          <td colspan="3" style="width: 81.72%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Voting Power<br>
              0</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 15.52%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">8</div>
          </td>
          <td colspan="3" style="width: 9.21%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Voting Power<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 15.52%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">9</div>
          </td>
          <td colspan="3" style="width: 9.21%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Dispositive Power<br>
              0</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 15.52%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">10</div>
          </td>
          <td colspan="3" style="width: 9.21%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Dispositive Power<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">11</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">12</div>
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          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)&#160;&#160;<font style="color: #000000;">&#9746;</font><sup style="color: #000000; vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
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            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">13</div>
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            <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (11)<br>
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          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.57%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">14</div>
          </td>
          <td colspan="5" style="width: 90.13%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)<br>
              CO</div>
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          <td style="width: 3.57%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 6.3%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 3.47%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 4.94%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td colspan="2" style="width: 1.35%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 80.37%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
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    <div>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
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            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">In addition to an aggregate of 7,213,012 shares of common stock in the aggregate held outright, the reporting persons hold in the aggregate warrants to
              purchase 9,017,055 shares of common stock; however, the provisions of such warrants restrict the exercise of such warrants to the extent that, after giving effect to such exercise, the holder of the warrants and its affiliates, together with
              any other person or entities with which such holder would constitute a group, would beneficially own in excess of 9.99% of the number of shares of common stock outstanding immediately after giving effect to such exercise (the &#8220;<u>Beneficial
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          <td style="width: 92.31%; vertical-align: top; font-family: 'Times New Roman';">&#160;</td>
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          <td style="width: 7.69%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">2</sup></div>
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            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">Based on a total of 84,889,593 shares, including (i) 83,622,135 shares outstanding, as reported by the Issuer in its Definitive Proxy Statement, filed with
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        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
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        <tr>
          <td style="width: 32.98%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">CUSIP No. <font style="color: #000000;">00289Y107</font></div>
          </td>
          <td style="width: 34.04%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
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    <div style="font-family: 'Times New Roman';">&#160;</div>
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        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">1</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div><font style="font-family: 'Times New Roman';">Name of Reporting Person<br>
              </font> <font style="color: rgb(0, 0, 0); font-family: 'Times New Roman';">Dr. Jeffrey R. Jay, M.D.</font></div>
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        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">2</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
          </td>
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        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">(a)</div>
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          <td colspan="2" style="width: 80.63%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;<font style="color: #000000;">&#9744;</font></div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">(b)</div>
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          <td colspan="2" style="width: 80.63%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;&#9744;</div>
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        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">3</div>
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          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">SEC Use Only</div>
          </td>
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        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">4</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Source of Funds (See Instructions)<br>
              AF</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">5</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)&#160; &#160;&#160;&#160;<font style="color: #000000;">&#9744;</font></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">6</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div><font style="font-family: 'Times New Roman';">Citizenship or Place of Organization<br>
              </font> <font style="color: rgb(0, 0, 0); font-family: 'Times New Roman';">United States</font></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td colspan="3" rowspan="7" style="width: 13.46%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Number of<br>
              Shares<br>
              Beneficially<br>
              Owned by<br>
              Each<br>
              Reporting<br>
              Person With</div>
          </td>
          <td style="width: 4.94%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">7</div>
          </td>
          <td colspan="3" style="width: 81.6%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Voting Power<br>
              0</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
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          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">8</div>
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          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Voting Power<br>
              8,480,470</div>
          </td>
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        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">9</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Dispositive Power<br>
              0</div>
          </td>
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        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">10</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Dispositive Power<br>
              8,480,470</div>
          </td>
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        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">11</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">12</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)&#160; &#9746;<sup style="color: #000000; vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
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        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">13</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (11)<br>
              9.99%<sup style="color: #000000; vertical-align: text-top; line-height: 1; font-size: smaller;">2</sup></div>
          </td>
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          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
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          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">14</div>
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            <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)<br>
              IN, HC</div>
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          <td style="width: 3.69%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 6.3%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 3.47%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 4.94%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
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            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">In addition to an aggregate of 7,213,012 shares of common stock in the aggregate held outright, the reporting persons hold in the aggregate warrants to
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          <td style="width: 7.69%; vertical-align: top; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 92.31%; vertical-align: top; font-family: 'Times New Roman';">&#160;</td>
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          <td style="width: 7.69%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">2</sup></div>
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            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">Based on a total of 84,889,593 shares, including (i) 83,622,135 shares outstanding, as reported by the Issuer in its Definitive Proxy Statement, filed with
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    <div><font style="font-family: 'Times New Roman';"><br>
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            <div style="font-family: 'Times New Roman';">CUSIP No. <font style="color: #000000;">00289Y107</font></div>
          </td>
          <td style="width: 34.04%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
          </td>
          <td style="width: 32.98%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
        </tr>

    </table>
    <div style="font-family: 'Times New Roman';">&#160;</div>
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        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">1</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div><font style="font-family: 'Times New Roman';">Name of Reporting Person<br>
              </font> <font style="color: rgb(0, 0, 0); font-family: 'Times New Roman';">Mr. David Kroin</font></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">2</div>
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          <td colspan="5" style="width: 90.01%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">(a)</div>
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          <td colspan="2" style="width: 80.63%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;<font style="color: #000000;">&#9744;</font></div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle;">
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          <td colspan="2" style="width: 80.63%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">&#160;<font style="color: #000000;">&#9744;</font></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">3</div>
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          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">SEC Use Only</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">4</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Source of Funds (See Instructions)<br>
              AF</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">5</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)&#160; &#160;&#160; &#9744;</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">6</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div><font style="font-family: 'Times New Roman';">Citizenship or Place of Organization<br>
              </font> <font style="color: rgb(0, 0, 0); font-family: 'Times New Roman';">United States</font></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td colspan="3" rowspan="7" style="width: 13.46%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">Number of<br>
              Shares<br>
              Beneficially<br>
              Owned by<br>
              Each<br>
              Reporting<br>
              Person With</div>
          </td>
          <td style="width: 4.94%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">7</div>
          </td>
          <td colspan="3" style="width: 81.6%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Voting Power<br>
              0</div>
          </td>
        </tr>
        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">8</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Voting Power<br>
              8,480,470</div>
          </td>
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        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">9</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Sole Dispositive Power<br>
              0</div>
          </td>
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        <tr>
          <td colspan="4" style="width: 15.68%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">10</div>
          </td>
          <td colspan="3" style="width: 9.38%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Shared Dispositive Power<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: middle;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">11</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person<br>
              8,480,470</div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">12</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)&#160;&#160;<font style="color: #000000;">&#9746;</font><sup style="color: #000000; vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">13</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (11)<br>
              9.99%<sup style="color: #000000; vertical-align: text-top; line-height: 1; font-size: smaller;">2</sup></div>
          </td>
        </tr>
        <tr>
          <td colspan="7" style="width: 100%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 3.69%; vertical-align: middle;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
          <td style="width: 6.3%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">14</div>
          </td>
          <td colspan="5" style="width: 90.01%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)<br>
              IN, HC</div>
          </td>
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        <tr>
          <td style="width: 3.69%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 6.3%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 3.47%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 4.94%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td colspan="2" style="width: 1.4%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 80.2%; vertical-align: middle; font-family: 'Times New Roman';">&#160;</td>
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    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div style="font-family: Arial,Helvetica,sans-serif;">
      <hr noshade="noshade" align="left" style="height: 1px; width: 10%; color: #000000; background-color: #000000; margin-left: 0px; margin-right: auto; border: none;"> </div>
    <table cellspacing="0" cellpadding="0" style="font-family: Arial, Helvetica, sans-serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="ze6d7f787d65e4444afea628cd219a143">

        <tr>
          <td style="width: 7.69%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">1</sup></div>
          </td>
          <td style="width: 92.31%; vertical-align: top;">
            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">In addition to an aggregate of 7,213,012 shares of common stock in the aggregate held outright, the reporting persons hold in the aggregate warrants to
              purchase 9,017,055 shares of common stock; however, the provisions of such warrants restrict the exercise of such warrants to the extent that, after giving effect to such exercise, the holder of the warrants and its affiliates, together with
              any other person or entities with which such holder would constitute a group, would beneficially own in excess of the Beneficial Ownership Cap. As a result, an aggregate of 1,267,458 shares underlying such warrants are beneficially owned by
              the reporting persons.</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7.69%; vertical-align: top; font-family: 'Times New Roman';">&#160;</td>
          <td style="width: 92.31%; vertical-align: top; font-family: 'Times New Roman';">&#160;</td>
        </tr>
        <tr>
          <td style="width: 7.69%; vertical-align: top;">
            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman';"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">2</sup></div>
          </td>
          <td style="width: 92.31%; vertical-align: top;">
            <div style="text-align: justify; color: rgb(0, 0, 0); font-family: 'Times New Roman';">Based on a total of 84,889,593 shares, including (i) 83,622,135 shares outstanding, as reported by the Issuer in its Definitive Proxy Statement, filed with
              the SEC on April 10, 2020 and (ii) 1,267,458 shares of the Issuer&#8217;s common stock issuable upon exercise of warrants held by the reporting persons (subject to the Beneficial Ownership Cap).</div>
          </td>
        </tr>

    </table>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div id="DSPFPageNumberArea" style="text-align: center;"><font id="DSPFPageNumber" style="font-family: Arial, Helvetica, 'sans-serif'; font-size: 8pt; font-weight: normal; font-style: normal;">4</font></div>
      <div style="page-break-after:always;" id="DSPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
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        <tr>
          <td style="width: 32.98%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">CUSIP No. <font style="color: #000000;">00289Y107</font></div>
          </td>
          <td style="width: 34.04%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
          </td>
          <td style="width: 32.98%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
        </tr>

    </table>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">This amendment No.&#160;1 to Schedule 13D (this &#8220;<font style="color: #000000;"><u>Amendment No.&#160;1</u></font>&#8221;) amends and supplements the Schedule 13D filed on December 30, 2019 (the &#8220;<font style="color: #000000;"><u>Initial Statement</u></font>&#8221; and, as amended and supplemented through the date of this Amendment No.&#160;1, collectively, the &#8220;<font style="color: #000000;"><u>Statement</u></font>&#8221;), by the undersigned, relating to <font style="color: #000000;">the common stock, $0.01 par value per share (the &#8220;</font><font style="color: #000000;"><u>Common Stock</u></font><font style="color: #000000;">&#8221;), of Abeona Therapeutics Inc., a Delaware corporation (the &#8220;</font><font style="color: #000000;"><u>Company</u></font><font style="color: #000000;">&#8221; or the &#8220;</font><font style="color: #000000;"><u>Issuer</u></font><font style="color: #000000;">&#8221;)</font>. Capitalized terms used and not defined in this Amendment No.&#160;1
      shall have the meanings ascribed to them in the Statement.</div>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">The information set forth in response to each separate Item below shall be deemed to be a response to all Items where such information is relevant.</div>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">Except as specifically supplemented by this Amendment No.&#160;1, the Statement is unchanged.&#160;</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div>
      <div>
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              <td style="width: 0pt;"><font style="font-family: 'Times New Roman';"><br>
                </font> </td>
              <td style="width: 72.05pt; vertical-align: top; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">Item&#160;4.</td>
              <td style="width: auto; vertical-align: top;">
                <div style="color: #000000;"><font style="font-family: 'Times New Roman'; font-size: 3pt;">&#160; </font><font style="font-weight: bold; font-family: 'Times New Roman';">Purpose of Transaction</font></div>
              </td>
            </tr>

        </table>
      </div>
    </div>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">Item 4 of the Initial Statement is amended to add the following paragraph at the end thereof:</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">As described in Item 6 below, the Reporting Persons are parties to the Letter Agreement with the Issuer, pursuant to which the Reporting Persons received the right to identify two
      candidates to be nominated to the Issuer&#8217;s board of directors (the &#8220;<u>Board</u>&#8221;), including the Executive Chairman of the Board. On April 21, 2020, the Issuer announced the appointment of Brian Pereira, M.D. as the Executive Chairman of the Board
      and Shawn Tomasello as an Independent Director. Each of Dr. Pereira and Ms. Tomasello were nominated by the Reporting Persons pursuant to the Letter Agreement.</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
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        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
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        <tr>
          <td style="width: 33.71%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="font-family: 'Times New Roman';">CUSIP No.&#160;<font style="color: #000000;">00289Y107</font></div>
          </td>
          <td style="width: 33.75%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
          </td>
          <td style="width: 32.54%; vertical-align: middle; border-bottom: #000000 2px double;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
          </td>
        </tr>

    </table>
    <div style="font-family: 'Times New Roman';">&#160;</div>
    <div><font style="font-weight: bold; font-family: 'Times New Roman';">&#160;Item 5.</font><font style="font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="font-weight: bold;">Interest in Securities of the Issuer</font></font></div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">Item 5 of the Initial Statement is amended and restated in its entirety to read as follows:</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">BVF is the record holder of 2,445,211 shares of Common Stock (the &#8220;<u>BVF Shares</u>&#8221;). Such shares constitute 2.88% of the shares of Common Stock outstanding, computed in accordance
      with Rule 13d-3. BVF shares voting and dispositive power over the BVF Shares.</div>
    <div><font style="font-family: 'Times New Roman';"><br>
      </font> </div>
    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">BVF is the record holder of warrants to purchase an additional 3,056,782 shares of Common Stock (the &#8220;<u>BVF Warrants</u>&#8221;). As a result of the Beneficial Ownership Cap, 429,668 shares
      underlying such warrants are exercisable, which constitutes 0.51% of the shares of Common Stock outstanding, computed in accordance with Rule 13d-3.</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">BOVF is the record holder of 3,253,068 shares of Common Stock (the &#8220;<u>BOVF Shares</u>&#8221;). Such shares constitute 3.83% of the shares of Common Stock outstanding, computed in accordance
      with Rule 13d-3. BOVF shares voting and dispositive power over the BOVF Shares.</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">BOVF is the record holder of warrants to purchase an additional 4,066,691 shares of Common Stock (the &#8220;<u>BOVF Warrants</u>&#8221;). As a result of the Beneficial Ownership Cap, 571,624 shares
      underlying such warrants are exercisable, which constitutes 0.67% of the shares of Common Stock outstanding, computed in accordance with Rule 13d-3.</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">GEF-SMA is the record holder of 1,514,733 shares of Common Stock (the &#8220;<u>GEF-SMA Shares</u>&#8221;). Such shares constitute 1.79% of the shares of Common Stock outstanding, computed in
      accordance with Rule 13d-3. GEF-SMA shares voting and dispositive power over the GEF-SMA Shares.</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">GEF-SMA is the record holder of warrants to purchase an additional 1,893,582 shares of Common Stock (the &#8220;<u>GEF-SMA Warrants</u>&#8221;). As a result of the Beneficial Ownership Cap, 266,166
      shares underlying such warrants are exercisable, which constitutes 0.31% of the shares of Common Stock outstanding, computed in accordance with Rule 13d-3.</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">BVF, BOVF and GEF-SMA (BVF, BOVF, and GEF-SMA, collectively, the &#8220;<u>Clients</u>&#8221;), and the Clients&#8217; respective general partners have granted full investment and voting authority and
      discretion to Great Point, as a result of which Great Point may be deemed to be the beneficial owner of the BVF Shares, the BOVF Shares and the GEF-SMA Shares. Each of Dr. Jay, as senior managing member of Great Point, and Mr. Kroin, and special
      managing member of Great Point, has shared voting and investment power with respect to the BVF Shares, the BOVF Shares, and the GEF-SMA Shares and may be deemed to be the beneficial owner of such shares. Great Point, Dr. Jay and Mr. Kroin disclaim
      beneficial ownership of the BVF Shares, the BOVF Shares and the GEF-SMA Shares except to the extent of any pecuniary interest, and this Statement shall not be deemed to be an admission that they are the beneficial owners of such securities.</div>
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            <div style="font-family: 'Times New Roman';">CUSIP No. <font style="color: #000000;">00289Y107</font></div>
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            <div style="text-align: center; color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">SCHEDULE 13D</div>
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    <div style="text-indent: 24.5pt; font-family: 'Times New Roman';">After reasonable inquiry and to the best of each of the undersigned&#8217;s knowledge and belief, each of the undersigned certifies that the information set forth in this Statement is true,
      complete and correct.</div>
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    <div style="font-family: 'Times New Roman';">Dated: April 22, 2020</div>
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            <div style="color: rgb(0, 0, 0); font-weight: bold; font-family: 'Times New Roman';">GREAT POINT PARTNERS, LLC</div>
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            <div style="font-family: 'Times New Roman';">By:</div>
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            <div style="font-family: 'Times New Roman';">/s/ Jeffrey R. Jay</div>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
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            <div style="font-family: 'Times New Roman';">Senior Managing Member</div>
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            <div style="font-family: 'Times New Roman';">/s/ Jeffrey R. Jay</div>
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            <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman'; font-size: 1pt;">&#160;</div>
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            <div style="font-family: 'Times New Roman';">By:</div>
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            <div style="font-family: 'Times New Roman';">/s/ David Kroin</div>
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