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SCHEDULE OF OPTIONS ACTIVITY (Details) - $ / shares | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
2015 Equity Incentive Plan [Member] |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Beginning balance, Options, Outstanding options | 5,560,739 | 5,795,395
Beginning balance, Weighted- average exercise price, Outstanding options | $ 2.21 | $ 7.96
Options, Granted | 4,877,308 | 2,645,146
Weighted- average exercise price, Granted | $ 1.75 | $ 2.26
Options, Exercised | (630,675) | (77,560)
Weighted- average exercise price, Exercised | $ 1.32 | $ 2.28
Options, Expired/forfeited | (1,952,521) | (2,802,242)
Weighted- average exercise price, Expired/forfeited | $ 4.07 | $ 6.52
Ending balance, Options, Outstanding options | 7,854,851 | 5,560,739
Ending balance, Options, Outstanding options | $ 1.54 | $ 2.21
Options, Non-vested options | 4,720,304 | 2,507,203
Weighted- average exercise price, Non-vested options | $ 1.64 | $ 1.29
2005 Equity Incentive Plan [Member] |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Beginning balance, Options, Outstanding options | 124,800 | 260,000
Beginning balance, Weighted- average exercise price, Outstanding options | $ 8.55 | $ 12.94
Options, Expired/forfeited | (44,800) | (135,200)
Weighted- average exercise price, Expired/forfeited | $ 21.53 | $ 6.80
Ending balance, Options, Outstanding options | 80,000 | 124,800
Ending balance, Options, Outstanding options | $ 1.28 | $ 8.55

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- Definition For presentations that combine terminations, the number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan or that expired. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(3)-(4) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Weighted average price of options that were either forfeited or expired. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(3)-(4) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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