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STOCK-BASED COMPENSATION (Tables)

3 Months Ended

Mar. 31, 2022

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

SCHEDULE OF STOCK BASED COMPENSATION

The following table summarizes stock-based compensation expense for the three months ended March 31, 2022 and 2021:

 SCHEDULE OF STOCK BASED COMPENSATION

(in thousands)		2022				2021
		For the three months ended March 31,
(in thousands)		2022				2021
Research and development		$	372			$	1,155
General and administrative			490				795
Stock based compensation expense		$	862			$	1,950

SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED

The Company estimated the fair value of stock options granted in the periods presented utilizing a Black-Scholes option-valuation model utilizing the following assumptions:

 SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED

		2022				2021
		For the three months ended March 31,
		2022				2021
Expected volatility			95	%			99	%
Expected term			6.08 years				6.08 years
Risk-free interest rate			1.73	%			1.00	%
Expected dividend yield			0	%			0	%

SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY

The following table summarizes restricted stock award activity during the three months ended March 31, 2022:

 SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY

		Number of Awards				Weighted Average Grant Date Fair Value
Outstanding at December 31, 2021			2,431,515			$	1.86
Granted			252,000			$	0.28
Cancelled/forfeited			(377,523	)		$	1.58
Vested			(357,658	)		$	2.31
Outstanding at March 31, 2022			1,948,334			$	1.63

2015 Equity Incentive Plan [Member]

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

SCHEDULE OF STOCK OPTIONS ACTIVITY

The following table summarizes stock option activity for the 2015 Incentive Plan during the three months ended March 31, 2022 :

 SCHEDULE OF STOCK OPTIONS ACTIVITY

		Number of Options				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (years)				Aggregate Intrinsic Value (in thousands)
Outstanding at December 31, 2021			7,854,851			$	1.54				7.63			$	-
Granted			104,000			$	0.26				-			$	-
Cancelled/forfeited			(937,048	)		$	1.40				-			$	-
Exercised			-			$	-				-			$	-
Outstanding at March 31, 2022			7,021,803			$	1.54				7.24			$	6
Exercisable			3,516,716			$	1.51				5.49			$	-
Unvested			3,505,087			$	1.57				8.98			$	6

2005 Equity Incentive Plan [Member]

Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]

SCHEDULE OF STOCK OPTIONS ACTIVITY

The following table summarizes stock option activity for the 2005 Incentive Plan during the three months ended March 31, 2022 :

SCHEDULE OF STOCK OPTIONS ACTIVITY

		Number of Options				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (years)				Aggregate Intrinsic Value (in thousands)
Outstanding at December 31, 2021			80,000			$	1.28				1.80			$	-
Cancelled/forfeited			-			$	-				-			$	-
Exercised			-			$	-				-			$	-
Outstanding at March 31, 2022			80,000			$	1.28				1.54			$	-
Exercisable			80,000			$	1.28				1.54			$	-
Unvested			-			$	-				-			$	-

X

- Definition

Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year.

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