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STOCK-BASED COMPENSATION (Tables)
6 Months Ended
Jun. 30, 2023
Share-Based Payment Arrangement [Abstract]  
SCHEDULE OF STOCK BASED COMPENSATION

The following table summarizes stock-based compensation expense for the three and six months ended June 30, 2023 and 2022 (in thousands):

 

   2023   2022   2023   2022 
  

For the three months ended June 30,

  

For the six months ended June 30,

 
   2023   2022   2023   2022 
                     
Research and development  $218   $184   $404   $556 
General and administrative   709    540    1,293    1,030 
Total stock-based compensation expense  $927   $724   $1,697   $1,586 
SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED

The Company estimated the fair value of stock options granted in the periods presented utilizing a Black-Scholes option-valuation model utilizing the following assumptions:

 

   For the six months ended June 30, 
   2023*   2022 
         
Expected volatility   n/a    95.1% - 96.0% 
Expected term   n/a    6.07 - 6.08 years 
Risk-free interest rate   n/a    1.7% - 3.3% 
Expected dividend yield   n/a    0%

 

SCHEDULE OF STOCK OPTIONS ACTIVITY

The following table summarizes stock option activity for the 2015 Incentive Plan and the 2005 Incentive Plan during the six months ended June 30, 2023 (there were no stock options granted under the 2023 Incentive Plan during the six months ended June 30, 2023):

 

           Weighted Average     
       Weighted   Remaining   Aggregate 
   Number of   Average   Contractual Term   Intrinsic Value 
   Options   Exercise Price   (years)   (in thousands) 
                 
Outstanding at December 31, 2022   240,770   $37.04    6.42   $ 
Granted      $       $ 
Cancelled/forfeited   (10,047)  $36.19       $ 
Exercised      $       $ 
Outstanding at June 30, 2023   230,723   $37.08    5.82   $ 
Exercisable   169,637   $36.33    5.09   $ 
Unvested   61,086   $39.17    7.87   $ 
SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY

The following table summarizes restricted stock award activity for the 2023 Incentive Plan, 2015 Incentive Plan and Inducement Grants during the six months ended June 30, 2023:

 

       Weighted Average 
       Grant Date Fair 
   Number of Awards   Value Per Unit 
         
Outstanding at December 31, 2022   816,958   $5.35 
Granted   1,817,559   $3.96 
Cancelled/forfeited   (46,394)  $4.40 
Vested   (21,820)  $28.34 
Outstanding at June 30, 2023   2,566,303   $4.18