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STOCK-BASED COMPENSATION (Tables)
9 Months Ended
Sep. 30, 2023
Share-Based Payment Arrangement [Abstract]  
SCHEDULE OF STOCK BASED COMPENSATION

The following table summarizes stock-based compensation expense for the three and nine months ended September 30, 2023 and 2022 (in thousands):

  

   2023   2022   2023   2022 
   For the three months ended September 30,   For the nine months ended September 30, 
   2023   2022   2023   2022 
                 
Research and development  $339   $173   $743   $729 
General and administrative   1,218    459    2,511    1,489 
Total stock-based compensation expense  $1,557   $632   $3,254   $2,218 
SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED

The Company estimated the fair value of stock options granted in the periods presented utilizing a Black-Scholes option-pricing model utilizing the following assumptions:

  

   For the nine months ended September 30, 
    2023*   2022 
           
Expected volatility (%)   n/a    95.1% - 96.0% 
Expected term (years)   n/a    6.07 - 6.08 years 
Risk-free interest rate (%)   n/a    1.7% - 3.3% 
Expected dividend yield (%)   n/a    0%
SCHEDULE OF STOCK OPTION ACTIVITY

The following table summarizes stock option activity for the 2015 Incentive Plan and the 2005 Incentive Plan during the nine months ended September 30, 2023 (there were no stock options granted under the 2023 Incentive Plan during the nine months ended September 30, 2023):

 

    Number of Options   Weighted Average Exercise Price   Weighted Average Remaining Contractual Term (years)   Aggregate Intrinsic Value
(in thousands)
 
                  
Outstanding at December 31, 2022    240,770   $37.04    6.42   $ 
Granted        $       $ 
Cancelled/forfeited    (17,447)  $33.40       $ 
Exercised       $       $ 
Outstanding at September 30, 2023    223,323   $37.33    5.69   $ 
Exercisable    170,958   $36.81    5.09   $ 
Unvested    52,365   $39.03    7.65   $ 

SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY

The following table summarizes restricted stock award activity for the 2023 Incentive Plan, 2015 Incentive Plan and Inducement Grants during the nine months ended September 30, 2023:

  

    Number of Awards   Weighted Average Grant Date Fair Value Per Unit 
          
Outstanding at December 31, 2022    816,958   $5.35 
Granted    1,817,559   $3.96 
Cancelled/forfeited    (56,398)  $4.32 
Vested    (269,195)  $5.44 
Outstanding at September 30, 2023    2,308,924   $4.27