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STOCK-BASED COMPENSATION (Tables) | 12 Months Ended
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Dec. 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
SCHEDULE OF STOCK BASED COMPENSATION | The following table summarizes stock-based compensation (in thousands): SCHEDULE OF STOCK BASED COMPENSATION
|  | 2023 |  |  | 2022 |
|  | For the year ended December 31, |
|  | 2023 |  |  | 2022 |
Research and development |  | $ | 1,085 |  |  | $ | 925 |
General and administrative |  |  | 3,683 |  |  |  | 2,126 |
Total stock-based compensation expense |  | $ | 4,768 |  |  | $ | 3,051 |
SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED | The Company estimated the fair value of stock options granted in the periods presented utilizing a Black-Scholes option-pricing model utilizing the following assumptions: SCHEDULE OF WEIGHTED-AVERAGE ASSUMPTIONS TO ESTIMATE THE FAIR VALUE OF THE OPTIONS GRANTED
|  | For the year ended December 31, |
|  | 2023* |  |  | 2022 |
Expected volatility (%) |  |  | n/a |  |  |  | 95.1% - 96.0% |
Expected term (years) |  |  | n/a |  |  |  | 6.07 - 6.08 years |
Risk-free interest rate (%) |  |  | n/a |  |  |  | 1.7% - 3.3% |
Expected dividend yield (%) |  |  | n/a |  |  |  | 0% |
* | the Company did not grant any stock options in the year ended December 31, 2023.
SCHEDULE OF STOCK OPTION ACTIVITY | The following table summarizes stock option activity for the 2015 Incentive Plan and the 2005 Incentive Plan during (there were no stock options granted under the 2023 Incentive Plan or the Inducement Plan during the year ended December 31, 2023): SCHEDULE OF STOCK OPTION ACTIVITY
|  | Number of Options |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Term (years) |  |  | Aggregate Intrinsic Value (in thousands) |
Outstanding at December 31, 2021 |  |  | 317,394 |  |  | $ | 38.40 |  |  |  | 7.57 |  |  | $ | — |
Granted |  |  | 7,760 |  |  | $ | 5.30 |  |  |  | — |  |  | $ | — |
Cancelled/forfeited |  |  | (84,384 | ) |  | $ | 39.25 |  |  |  | — |  |  | $ | — |
Exercised |  |  | — |  |  | $ | — |  |  |  | — |  |  | $ | — |
Outstanding at December 31, 2022 |  |  | 240,770 |  |  | $ | 37.04 |  |  |  | 6.42 |  |  | $ | — |
Granted |  |  | — |  |  | $ | — |  |  |  | — |  |  | $ | — |
Cancelled/forfeited |  |  | (61,769 | ) |  | $ | 32.59 |  |  |  | — |  |  | $ | — |
Exercised |  |  | — |  |  | $ | — |  |  |  | — |  |  | $ | — |
Outstanding at December 31, 2023 |  |  | 179,001 |  |  | $ | 38.58 |  |  |  | 6.83 |  |  | $ | 3 |
Exercisable |  |  | 135,271 |  |  | $ | 38.49 |  |  |  | 6.64 |  |  | $ | 1 |
Unvested |  |  | 43,730 |  |  | $ | 38.85 |  |  |  | 7.43 |  |  | $ | 2 |
SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY | The following table summarizes restricted stock award activity: SCHEDULE OF RESTRICTED STOCK AWARD ACTIVITY
|  | Number of Awards |  |  | Weighted Average Grant Date Fair Value Per Unit |
Outstanding at December 31, 2021 |  |  | 97,260 |  |  | $ | 46.50 |
Granted |  |  | 779,722 |  |  | $ | 3.12 |
Cancelled/forfeited |  |  | (32,498 | ) |  | $ | 38.80 |
Vested |  |  | (27,526 | ) |  | $ | 48.63 |
Outstanding at December 31, 2022 |  |  | 816,958 |  |  | $ | 5.35 |
Granted |  |  | 1,958,159 |  |  | $ | 3.99 |
Cancelled/forfeited |  |  | (56,398 | ) |  | $ | 4.32 |
Vested |  |  | (270,550 | ) |  | $ | 5.59 |
Outstanding at December 31, 2023 |  |  | 2,448,169 |  |  | $ | 4.25 |
2015 Equity Incentive Plan [Member] |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
SCHEDULE OF OPTIONS OUTSTANDING AND EXERCISABLE | As of December 31, 2023, there are no options outstanding under the 2005 Incentive Plan. Further information regarding options outstanding under the 2015 Incentive Plan as of December 31, 2023 is summarized below: SCHEDULE OF OPTIONS OUTSTANDING AND EXERCISABLE
|  |  |  |  |  | Weighted-Average |  |  |  |  |  | Weighted-Average |
Range of Exercise Prices |  |  | Number of Options Outstanding |  |  | Remaining Life in Years |  |  | Exercise Price |  |  | Number of Options Exercisable |  |  | Remaining Life in Years |  |  | Exercise Price |
$ | 4.00 |  |  | $ | 22.75 |  |  |  | 20,240 |  |  |  | 8.0 |  |  | $ | 16.52 |  |  |  | 10,117 |  |  |  | 7.9 |  |  | $ | 17.47 |
| 25.50 |  |  |  | 47.00 |  |  |  | 106,081 |  |  |  | 6.5 |  |  |  | 33.45 |  |  |  | 88,874 |  |  |  | 6.3 |  |  |  | 33.09 |
| 54.50 |  |  |  | 58.50 |  |  |  | 52,480 |  |  |  | 7.2 |  |  |  | 56.98 |  |  |  | 36,080 |  |  |  | 7.2 |  |  |  | 56.98 |
| 164.75 |  |  |  | 183.50 |  |  |  | 200 |  |  |  | 5.1 |  |  |  | 164.75 |  |  |  | 200 |  |  |  | 5.1 |  |  |  | 164.75 |
|  |  |  |  |  |  |  |  | 179,001 |  |  |  |  |  |  |  |  |  |  |  | 135,271 |  |  |  |  |  |  |  |  |

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