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Income Taxes, Primary Factors Affecting Income Tax Rates (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2024 | Dec. 31, 2023
Primary Factors Affecting Income Tax Rates [Abstract] |  |
Tax benefit at U.S. statutory rates | (21.00%) | (21.00%)
State tax benefit | (2.50%) | (3.40%)
Permanent differences | 0.10% | 0.90%
Other | (4.00%) | 2.30%
Changes in valuation allowance | 27.40% | 21.20%
Income tax rate, total | 0.00% | 0.00%
Federal and Sate [Abstract] |  |
Deferred tax asset valuation allowance percentage in each of the last two years | 100.00% |
Operating loss carryforwards expiration year | 2037 |
Federal and state research and development credits expiration year | 2042 |
Federal [Member] |  |
Federal and Sate [Abstract] |  |
Research and development credits | $ 7,764,000 |
Federal [Member] | Expiring as a Result of 2017 Tax Act [Member] |  |
Federal and Sate [Abstract] |  |
Net operating loss carryforwards | 131,579,000 |
Federal [Member] | Expiring Through 2037 [Member] |  |
Federal and Sate [Abstract] |  |
Net operating loss carryforwards | 120,055,000 |
State [Member] |  |
Federal and Sate [Abstract] |  |
Research and development credits | 1,245,000 |
State [Member] | Expiring as a Result of 2017 Tax Act [Member] |  |
Federal and Sate [Abstract] |  |
Net operating loss carryforwards | 137,878,000 |
State [Member] | Expiring Through 2037 [Member] |  |
Federal and Sate [Abstract] |  |
Net operating loss carryforwards | $ 102,003,000 |

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