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Segments - Significant Expense Categories (Details)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
USD ($)
Segment
Dec. 31, 2023
USD ($)
Operating expenses [Abstract]    
Research and development $ 36,571 $ 32,130
General and administrative 5,862 5,942
Total operating expenses 42,433 38,072
Total operating loss (42,433) (38,072)
Other income (expense) [Abstract]    
Interest income 338 230
Interest expense (5,540) (2,792)
Change in fair value of derivatives 588 (432)
Total other expense (4,614) (2,994)
Net loss (47,047) (41,066)
Preferred stock dividends (153) (120)
Warrant modification 0 (3,619)
Net loss applicable to common stockholders $ (47,200) (44,805)
Number of operating segment | Segment 1  
Net cash used in operating activities $ (41,767) (32,965)
Business Operating Segment [Member]    
Operating expenses [Abstract]    
Research and development 36,571 32,130
General and administrative 5,862 5,942
Total operating expenses 42,433 38,072
Total operating loss (42,433) (38,072)
Other income (expense) [Abstract]    
Interest income 336 230
Interest expense (5,540) (2,792)
Change in fair value of derivatives 590 (432)
Total other expense (4,614) (2,994)
Net loss (47,047) (41,066)
Preferred stock dividends (153) (120)
Warrant modification 0 (3,619)
Net loss applicable to common stockholders $ (47,200) $ (44,805)