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v3.25.1

Nature of Business (Details) $ / shares in Units, $ in Thousands |  |  |  |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended | 195 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
May 02, 2025 USD ($) | Apr. 30, 2025 $ / shares shares | Feb. 18, 2025 USD ($) | Apr. 30, 2024 USD ($) increment | Aug. 10, 2023 shares | Oct. 31, 2023 USD ($) | Mar. 31, 2025 USD ($) $ / shares shares | Mar. 31, 2024 USD ($) | Dec. 31, 2021 | Mar. 31, 2025 USD ($) $ / shares | Dec. 31, 2024 USD ($) $ / shares | Dec. 31, 2023 USD ($)
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Cash, cash equivalents and restricted cash, |  |  |  |  |  |  | $ 13,350 | $ 4,320 |  | $ 13,350 | $ 8,875 | $ 12,127
Accumulated deficit |  |  |  |  |  |  | 289,924 |  |  | 289,924 | $ 279,549 |
Issuance of stock |  |  |  |  |  |  |  | 3,141 |  | $ 300 |  |
Sale of stock (in shares) | shares |  |  |  |  | 4,015,002 |  |  |  |  |  |  |
Proceeds from lines of credit |  |  | $ 10,000 | $ 25,000 |  |  | $ 10,000 | $ 0 |  |  |  |
Number of debt increments available to be drawn | increment |  |  |  | 2 |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.0001 |  |  | $ 0.0001 | $ 0.0001 |
University Of Texas MD Anderson Cancer Center |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Alliance program, term |  |  |  |  |  |  |  |  | 5 years |  |  |
Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ / shares |  | $ 0.0001 |  |  |  |  |  |  |  |  |  |
Loan Facility | Secured Debt |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Line of credit maximum borrowing capacity |  |  |  | $ 50,000 |  |  |  |  |  |  |  |
Proceeds from lines of credit |  |  | $ 10,000 | 25,000 |  |  |  |  |  |  |  |
Loan Facility, June 30, 2025 | Secured Debt |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Line of credit maximum borrowing capacity |  |  |  | 10,000 |  |  |  |  |  |  |  |
Loan Facility, December 31, 2025 | Secured Debt |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Line of credit maximum borrowing capacity |  |  |  | $ 15,000 |  |  |  |  |  |  |  |
Standby Equity Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Sale of stock, authorized amount |  |  |  |  |  | $ 30,000 | $ 30,000 |  |  |  |  |
Sale of stock (in shares) | shares |  |  |  |  |  |  | 0 |  |  |  |  |
Private Placement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |
Nature of Business [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Sale of stock, shares to be issued in transaction (in shares) | shares |  | 5,500,000 |  |  |  |  |  |  |  |  |  |
Stock net yet issued, price per share (in dollars per share) | $ / shares |  | $ 4.00 |  |  |  |  |  |  |  |  |  |
Proceeds from private placement | $ 22,000 |  |  |  |  |  |  |  |  |  |  |

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