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Nature of Business (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended 195 Months Ended
May 02, 2025
USD ($)
Apr. 30, 2025
$ / shares
shares
Feb. 18, 2025
USD ($)
Apr. 30, 2024
USD ($)
increment
Aug. 10, 2023
shares
Oct. 31, 2023
USD ($)
Mar. 31, 2025
USD ($)
$ / shares
shares
Mar. 31, 2024
USD ($)
Dec. 31, 2021
Mar. 31, 2025
USD ($)
$ / shares
Dec. 31, 2024
USD ($)
$ / shares
Dec. 31, 2023
USD ($)
Nature of Business [Line Items]                        
Cash, cash equivalents and restricted cash,             $ 13,350 $ 4,320   $ 13,350 $ 8,875 $ 12,127
Accumulated deficit             289,924     289,924 $ 279,549  
Issuance of stock               3,141   $ 300    
Sale of stock (in shares) | shares         4,015,002              
Proceeds from lines of credit     $ 10,000 $ 25,000     $ 10,000 $ 0        
Number of debt increments available to be drawn | increment       2                
Common stock, par value (in dollars per share) | $ / shares             $ 0.0001     $ 0.0001 $ 0.0001  
University Of Texas MD Anderson Cancer Center                        
Nature of Business [Line Items]                        
Alliance program, term                 5 years      
Subsequent Event                        
Nature of Business [Line Items]                        
Common stock, par value (in dollars per share) | $ / shares   $ 0.0001                    
Loan Facility | Secured Debt                        
Nature of Business [Line Items]                        
Line of credit maximum borrowing capacity       $ 50,000                
Proceeds from lines of credit     $ 10,000 25,000                
Loan Facility, June 30, 2025 | Secured Debt                        
Nature of Business [Line Items]                        
Line of credit maximum borrowing capacity       10,000                
Loan Facility, December 31, 2025 | Secured Debt                        
Nature of Business [Line Items]                        
Line of credit maximum borrowing capacity       $ 15,000                
Standby Equity Purchase Agreement                        
Nature of Business [Line Items]                        
Sale of stock, authorized amount           $ 30,000 $ 30,000          
Sale of stock (in shares) | shares             0          
Private Placement | Subsequent Event                        
Nature of Business [Line Items]                        
Sale of stock, shares to be issued in transaction (in shares) | shares   5,500,000                    
Stock net yet issued, price per share (in dollars per share) | $ / shares   $ 4.00                    
Proceeds from private placement $ 22,000