<SEC-DOCUMENT>0001484612-25-000043.txt : 20250515
<SEC-HEADER>0001484612-25-000043.hdr.sgml : 20250515
<ACCEPTANCE-DATETIME>20250515175741
ACCESSION NUMBER:		0001484612-25-000043
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250515
DATE AS OF CHANGE:		20250515

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Outset Medical, Inc.
		CENTRAL INDEX KEY:			0001484612
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				200514392
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-39513
		FILM NUMBER:		25956239

	BUSINESS ADDRESS:	
		STREET 1:		3052 ORCHARD DRIVE
		CITY:			SAN JOSE
		STATE:			CA
		ZIP:			95134
		BUSINESS PHONE:		669-231-8200

	MAIL ADDRESS:	
		STREET 1:		3052 ORCHARD DRIVE
		CITY:			SAN JOSE
		STATE:			CA
		ZIP:			95134

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Home Dialysis Plus, Ltd.
		DATE OF NAME CHANGE:	20100219

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Trigg Leslie
		CENTRAL INDEX KEY:			0001304125
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		144

	MAIL ADDRESS:	
		STREET 1:		C/O OUTSET MEDICAL
		STREET 2:		1830 BERING ROAD
		CITY:			SAN JOSE
		STATE:			CA
		ZIP:			95112
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001304125</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001484612</issuerCik>
      <issuerName>Outset Medical, Inc.</issuerName>
      <secFileNumber>001-39513</secFileNumber>
      <issuerAddress>
        <com:street1>3052 ORCHARD DRIVE</com:street1>
        <com:city>SAN JOSE</com:city>
        <com:stateOrCountry>CA</com:stateOrCountry>
        <com:zipCode>95134</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>669-231-8200</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Trigg Leslie</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Smith Barney LLC</name>
        <address>
          <com:street1>1 New York Plaza, 38th Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10004</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>935</noOfUnitsSold>
      <aggregateMarketValue>16646.12</aggregateMarketValue>
      <noOfUnitsOutstanding>17722310</noOfUnitsOutstanding>
      <approxSaleDate>05/15/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <acquiredDate>05/15/2025</acquiredDate>
      <natureOfAcquisitionTransaction>Settlement of Vested Restricted Stock Units</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>1770</amountOfSecuritiesAcquired>
      <paymentDate>05/15/2025</paymentDate>
      <natureOfPayment>Equity compensation for services rendered</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Leslie Trigg</name>
        <address>
          <com:street1>3052 Orchard Drive</com:street1>
          <com:city>San Jose</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>95134</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <saleDate>02/18/2025</saleDate>
      <amountOfSecuritiesSold>974</amountOfSecuritiesSold>
      <grossProceeds>13149.90</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>Shares sold to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. This sale was made to satisfy tax withholding obligations through a sell-to-cover transaction and does not represent a discretionary trade by the reporting person.  Securities sold during the past 3 months have been adjusted retroactively to reflect the reverse stock split that was effected on March 20, 2025.</remarks>
    <noticeSignature>
      <noticeDate>05/15/2025</noticeDate>
      <signature>John Brottem POA for Leslie Trigg</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
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</TEXT>
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</SEC-DOCUMENT>
