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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2024 | Sep. 30, 2023
Cash flows from operating activities |  |
Net loss | $ (86,202) | $ (91,602)
Adjustments to reconcile net loss to net cash used in operations: |  |
Depreciation expense | 2,663 | 2,600
Non-cash lease expense | 3,752 | 3,513
Stock-based compensation | 8,138 | 11,468
Interest amortization on marketable securities | (1,137) | (3,674)
Changes in operating assets and liabilities: |  |
Operating lease liabilities | (2,806) | (2,646)
Prepaid expenses and other current assets | (859) | 2,558
Accounts payable and accrued liabilities | (1,446) | 2,678
Other assets | 2,300 | (1,161)
Net cash used in operating activities | (75,597) | (76,266)
Cash flow from investing activities |  |
Purchases of marketable securities | (9,914) | (58,369)
Proceeds from maturities of marketable securities | 107,000 | 120,000
Purchases of property and equipment | (157) | (958)
Net cash provided by investing activities | 96,929 | 60,673
Cash flow from financing activities |  |
Payment of issuance costs related to underwritten public offering and concurrent private placement |  | (717)
Proceeds from the issuance of common stock from at-the-market sales agreement, net of issuance costs | 297 | 4,593
Repurchases of shares for tax withholdings upon vesting of restricted stock unit awards | (303) | (1,165)
Proceeds from stock option exercises and the issuance of shares under ESPP | 112 | 202
Net cash provided by financing activities | 106 | 2,913
Net decrease in cash, cash equivalents and restricted cash equivalents | 21,438 | (12,680)
Cash, cash equivalents and restricted cash equivalents, beginning of period | 33,773 | 60,119
Cash, cash equivalents and restricted cash equivalents, end of period | 55,211 | 47,439
Supplemental disclosure of non-cash activities |  |
Right-of-use assets obtained in exchange for lease obligations |  | 37
Purchases of property and equipment in accounts payable and accrued liabilities |  | 63
Financing costs associated with the sale of common stock included in accounts payable and accrued expenses | $ 22 | $ 30

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