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Segments - Summary of the Segment Profit or Loss, Including Significant Segment Expenses (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Segment Reporting Information [Line Items]    
Segment expenses $ 32,486 $ 30,804
Net loss (32,486) (30,804)
Trem-cel    
Segment Reporting Information [Line Items]    
Segment expenses 6,382 4,861
VCAR33    
Segment Reporting Information [Line Items]    
Segment expenses 3,636 2,600
Other Research and Development    
Segment Reporting Information [Line Items]    
Segment expenses 2,995 3,117
Salaries and Benefits    
Segment Reporting Information [Line Items]    
Segment expenses 11,613 12,113
General Corporate Activities    
Segment Reporting Information [Line Items]    
Segment expenses 5,169 5,299
Other Segment Items    
Segment Reporting Information [Line Items]    
Segment expenses $ 2,691 $ 2,814