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Accrued Expenses (Details) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Payables and Accruals [Abstract]
Payroll and employee related expenses	$ 1,840	$ 3,049
Collaboration and licensing	1,350	1,350
Accrued patent fees	471	534
Accrued external research and development costs	2,010	2,029
Accrued professional and consulting services	802	798
Accrued interest	170	170
Other	204	216
Accrued expenses	$ 6,847	$ 8,146

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Carrying value as of the balance sheet date of patent fees.

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.20)
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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.

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