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Consolidated Statements of Changes in Stockholders’ (Deficit) Equity - USD ($)
$ in Thousands
Total
Common stock
Additional paid-in capital
Accumulated deficit
Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2019   86,325,547      
Beginning balance at Dec. 31, 2019 $ 8,397 $ 9 $ 348,664 $ (335,753) $ (4,523)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   78,583      
Issuance of common stock under Employee Stock Purchase Plan 114   114    
Issuance of common stock upon exercise of options (in shares)   5,128      
Issuance of common stock upon exercise of options 3   3    
Issuance of vested restricted stock units (in shares)   10,937      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   598,977      
Issuance of common stock through at-the-market offering, net 1,141   1,141    
Other financing fees (147)   (147)    
Stock-based compensation expense 1,409   1,409    
Currency translation adjustment (60)       (60)
Unrealized (losses) on marketable securities 0        
Net loss (19,620)     (19,620)  
Ending balance (in shares) at Mar. 31, 2020   87,019,172      
Ending balance at Mar. 31, 2020 $ (8,763) $ 9 351,184 (355,373) (4,583)
Beginning balance (in shares) at Dec. 31, 2020 108,071,249 108,071,249      
Beginning balance at Dec. 31, 2020 $ (18,006) $ 11 391,175 (404,629) (4,563)
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock under Employee Stock Purchase Plan (in shares)   34,696      
Issuance of common stock under Employee Stock Purchase Plan 72   72    
Issuance of common stock upon exercise of options (in shares)   153,278      
Issuance of common stock upon exercise of options 244   244    
Issuance of vested restricted stock units (in shares)   10,937      
Issuance of vested restricted stock units 0        
Issuance of common stock through at-the-market offering, net (in shares)   4,706,844      
Issuance of common stock through at-the-market offering, net 20,943   20,943    
Stock-based compensation expense 1,780   1,780    
Currency translation adjustment (6)       (6)
Unrealized (losses) on marketable securities (1)       (1)
Net loss $ (24,597)     (24,597)  
Ending balance (in shares) at Mar. 31, 2021 112,977,004 112,977,004      
Ending balance at Mar. 31, 2021 $ (19,571) $ 11 $ 414,214 $ (429,226) $ (4,570)