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Segment Reporting
 12 Months Ended
Dec. 31, 2024
Segment Reporting [Abstract]  
Segment Reporting Segment Reporting
Factors used in determining the reportable segment include the nature of the Company’s operating activities, the organizational and reporting structure and the type of information reviewed by the CODM to allocate resources and evaluate financial performance. The accounting policies of the segment are the same as those described in Note 3.
The following table presents selected financial information with respect to the Company’s single operating segment for the years ended December 31, 2024 and 2023 (in thousands):
Year Ended December 31,
20242023
Revenue:
Collaboration and license revenue$38,275 $26,004 
Grant revenue638 — 
Total revenue38,913 26,004 
Less
Operating expenses:
Legacy Selecta programs6,150 31,826 
Descartes-08 for MG12,142 343 
Early stage programs1,028 595 
Research and development employee expenses11,952 18,363 
Research and development stock-based compensation expense3,217 12,985 
Research and development facilities and other expenses10,616 7,148 
General and administrative30,126 40,450 
Impairment of long-lived assets7,579 710 
Other expense, net (1)33,527 133,294 
Net loss$(77,424)$(219,710)
(1) Includes impairment of long-lived assets, interest income, foreign currency transaction, net, interest expense, change in fair value of warrant liabilities, change in fair value of contingent value right liability, change in fair value of forward contract liabilities, other income, net, and income tax (expense) benefit.