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Revenue Arrangements (Details) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024	Jun. 30, 2024	Jun. 28, 2024	Jan. 31, 2023	Jun. 30, 2020
Disaggregation of Revenue [Line Items]
Unsatisfied performance obligation	$ 0		$ 0
Accounts receivable	1,765		872
Grant revenue	700	$ 0
National Institute of Neurological Disorders and Stroke of the National Institutes of Health Funding
Disaggregation of Revenue [Line Items]
Government assistance, award amount				$ 1,500
Government assistance, potential additional award amount				$ 1,500
Government assistance, asset, current	1,300		600
Grant revenue	700
Astellas | License
Disaggregation of Revenue [Line Items]
Contract liability						$ 10,000
Future contingent additional payments						$ 340,000
Unsatisfied performance obligation	0
Accounts receivable	100		100
Revenue recognized	0	5,800
Revenue recognized from performance obligations related to prior periods as a result of change in transaction price		3,200
SOBI | License
Disaggregation of Revenue [Line Items]
Contract liability					$ 30,000		$ 75,000
Future contingent additional payments							$ 630,000
Accounts receivable	100		100
Revenue recognized	$ 0	$ 0	$ 30,000

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