<SEC-DOCUMENT>0001274173-18-000003-index.html : 20180110
<SEC-HEADER>0001274173-18-000003.hdr.sgml : 20180110
<ACCEPTANCE-DATETIME>20180110163446
ACCESSION NUMBER:		0001274173-18-000003
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20180110
DATE AS OF CHANGE:		20180110

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PUMA BIOTECHNOLOGY, INC.
		CENTRAL INDEX KEY:			0001401667
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				770683487
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-83367
		FILM NUMBER:		18521856

	BUSINESS ADDRESS:	
		STREET 1:		10880 WILSHIRE BLVD.
		STREET 2:		SUITE 2150
		CITY:			LOS ANGELES
		STATE:			CA
		ZIP:			90024
		BUSINESS PHONE:		(424) 248-6500

	MAIL ADDRESS:	
		STREET 1:		10880 WILSHIRE BLVD.
		STREET 2:		SUITE 2150
		CITY:			LOS ANGELES
		STATE:			CA
		ZIP:			90024

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INNOVATIVE ACQUISITIONS CORP
		DATE OF NAME CHANGE:	20070601

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			JANUS CAPITAL MANAGEMENT LLC
		CENTRAL INDEX KEY:			0000812295
		STANDARD INDUSTRIAL CLASSIFICATION:	UNKNOWN SIC - 0000 [0000]
		IRS NUMBER:				753019302
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		151 DETROIT ST.
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206-4805
		BUSINESS PHONE:		3033333863

	MAIL ADDRESS:	
		STREET 1:		151 DETROIT ST.
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206-4805

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL GROUP INC
		DATE OF NAME CHANGE:	20030103

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL MANAGEMENT LLC
		DATE OF NAME CHANGE:	20020424

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL CORP
		DATE OF NAME CHANGE:	19931213
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>pbyi1102018.txt
<DESCRIPTION>CLOSE OUT OF JANUS CAPITAL MGMT LLC & FILE UNDER NEW PARENT CO JANUS HENDERSON GROUP PLC AT 11.6%
<TEXT>
Document 1 - file: pbyi1102018.txt

</DOCUMENT>
</SEC-DOCUMENT>