    <SEC-DOCUMENT>0001437749-26-013673-index.html : 20260428
    <SEC-HEADER>0001437749-26-013673.hdr.sgml : 20260428
    <ACCEPTANCE-DATETIME>20260428161704
    ACCESSION NUMBER:		0001437749-26-013673
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260428
    DATE AS OF CHANGE:		20260428
    EFFECTIVENESS DATE:		20260428

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			PUMA BIOTECHNOLOGY, INC.
    		CENTRAL INDEX KEY:			0001401667
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				770683487
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-35703
    		FILM NUMBER:		26908066

    	BUSINESS ADDRESS:
    		STREET 1:		10880 WILSHIRE BLVD.
    		STREET 2:		SUITE 2150
    		CITY:			LOS ANGELES
    		STATE:			CA
    		ZIP:			90024
    		BUSINESS PHONE:		(424) 248-6500

    	MAIL ADDRESS:
    		STREET 1:		10880 WILSHIRE BLVD.
    		STREET 2:		SUITE 2150
    		CITY:			LOS ANGELES
    		STATE:			CA
    		ZIP:			90024

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	INNOVATIVE ACQUISITIONS CORP
    		DATE OF NAME CHANGE:	20070601
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>pbyi20260428_ars.pdf
    <DESCRIPTION>FORM ARS
    <TEXT>
    Document 1 - file: pbyi20260428_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>